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Elevated N‐methyltransferase expression induced by hepatic stellate cells contributes to the metastasis of hepatocellular carcinoma via regulation of the CD44v3 isoform

https://doi.org/10.1002/1878-0261.12544
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42/42 checkable references clean · checked 2026-07-24

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

6 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 42 checked references that resolve
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Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
resolves10.21037/tgh.2018.04.05
Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma
resolves10.1016/j.omtn.2018.03.011
Targeting Nicotinamide N-Methyltransferase and miR-449a in EGFR-TKI-Resistant Non-Small-Cell Lung Cancer Cells
resolves10.3390/ijms18091849
Activation of Matrix Hyaluronan-Mediated CD44 Signaling, Epigenetic Regulation and Chemoresistance in Head and Neck Cancer Stem Cells
resolves10.14715/cmb/2018.64.7.9
Involvement of transforming growth factor beta 1 in the transcriptional regulation of nicotinamide N-methyltransferase in clear cell renal cell carcinoma
resolves10.1016/S0021-9258(18)56110-X
METHYLATION OF NICOTINAMIDE WITH A SOLUBLE ENZYME SYSTEM FROM RAT LIVER
resolves10.3322/caac.21338
Cancer statistics in China, 2015
resolves10.1016/j.jhep.2014.02.003
Stellate cells and the development of liver cancer: Therapeutic potential of targeting the stroma
resolves10.1016/j.ccell.2018.05.003
Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling
resolves10.1038/nature11112
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
resolves10.1016/j.ccell.2016.09.004
p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer
resolves10.1038/nrg3778
Context-dependent control of alternative splicing by RNA-binding proteins
resolves10.1126/science.aad8711
Messenger RNA modifications: Form, distribution, and function
resolves10.1182/blood-2017-08-802462
Microenvironment-induced CD44v6 promotes early disease progression in chronic lymphocytic leukemia
resolves10.1038/nm.3882
Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization
resolves10.1007/s00018-017-2527-8
Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells
resolves10.1038/nchembio.687
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
resolves10.1038/nrc.2017.23
RNA editing-dependent epitranscriptome diversity in cancer stem cells
resolves10.1172/jci.insight.90019
Nicotinamide metabolism regulates glioblastoma stem cell maintenance
resolves10.21037/jgo.2017.06.09
How does the tumor microenvironment play a role in hepatobiliary tumors?
resolves10.1186/1756-9966-28-20
Expression of nicotinamide N-methyltransferase in hepatocellular carcinoma is associated with poor prognosis
resolves10.1016/j.matbio.2018.05.007
The CD44-HA axis and inflammation in atherosclerosis: A temporal perspective
resolves10.2119/molmed.2011.00258
Glycine N-Methyltransferase Deficiency Affects Niemann-Pick Type C2 Protein Stability and Regulates Hepatic Cholesterol Homeostasis
resolves10.1038/emm.2006.54
Overexpression of nicotinamide N-methyltransferase in gastric cancer tissues and its potential post-translational modification
resolves10.1002/cam4.1296
SALL4 ‐ KHDRBS3 network enhances stemness by modulating <scp>CD</scp>44 splicing in basal‐like breast cancer
resolves10.1186/s40164-018-0109-6
Emerging therapies in advanced hepatocellular carcinoma
resolves10.1093/ajcn/85.1.19
Methyl balance and transmethylation fluxes in humans
resolves10.1158/1078-0432.CCR-16-1323
NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability
resolves10.1016/j.cell.2017.05.003
The U6 snRNA m 6 A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention
resolves10.5301/ijbm.5000311
Clinical performance and utility of a NNMT-based urine test for bladder cancer
resolves10.1017/S0022215116008525
Expression of CD44 variant isoforms, CD44v3 and CD44v6, are associated with prognosis in nasopharyngeal carcinoma
resolves10.1038/nchembio.1234
Cancer mistunes methylation
resolves10.1186/s12876-015-0291-5
Hepatic stellate cells: central modulators of hepatic carcinogenesis
resolves10.1038/nchembio.1204
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
resolves10.1007/s00204-014-1435-z
Epigenetic silencing of microRNA-218 via EZH2-mediated H3K27 trimethylation is involved in malignant transformation of HBE cells induced by cigarette smoke extract
resolves10.1038/onc.2008.264
Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration
resolves10.18632/oncotarget.6839
Activated hepatic stellate cells promote liver cancer by induction of myeloid-derived suppressor cells through cyclooxygenase-2
resolves10.1159/000369731
Effects of Nicotinamide N-Methyltransferase on PANC-1 Cells Proliferation, Metastatic Potential and Survival Under Metabolic Stress
resolves10.1111/his.12637
Abnormal nuclear expression of Pygopus‐2 in human primary hepatocellular carcinoma correlates with a poor prognosis
resolves10.1038/labinvest.2013.139
Hepatic stellate cells promote tumor progression by enhancement of immunosuppressive cells in an orthotopic liver tumor mouse model
resolves10.1002/ijc.25920
Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice
resolves10.1016/j.molcel.2012.10.015
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
The 6 references without a DOI — listed, not checked
no DOI — not checkedPurification and cDNA cloning of the AdoMet‐binding subunit of the human mRNA (N6‐adenosine)‐methyltransferase
no DOI — not checkedNicotinamide N‐Methyltransferase upregulation correlates with tumour differentiation in oral squamous cell carcinoma
no DOI — not checkedNicotinamide N‐methyltransferase promotes epithelial‐mesenchymal transition in gastric cancer cells by activating transforming growth factor‐beta1 expression
no DOI — not checked[The effect of nicotinamide N‐methytransferase overexpression on biological behaviors of SMMC7721 hepatocellar carcinoma cell line]
no DOI — not checkedData‐independent acquisition‐based quantitative proteomic analysis reveals potential biomarkers of kidney
no DOI — not checkedNicotinamide N‐methyltransferase enhances the progression of prostate cancer by stabilizing sirtuin 1
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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