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Serial killing of tumor cells by cytotoxic T cells redirected with a CD19‐/CD3‐bispecific single‐chain antibody construct

https://doi.org/10.1002/ijc.20908
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23/23 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

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The 23 checked references that resolve
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Bispecific antibodies in cancer therapy
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The role of B7 co‐stimulation in activation and differentiation ofCD4<sup>+</sup>and CD8<sup>+</sup>T cells
resolves10.2174/1389450033490849
Tumor Escape from Immune Response: Mechanisms and Targets of Activity
resolves10.1016/S1357-4310(99)01451-3
HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story
resolves10.1016/S0002-9440(10)65321-7
Down-Regulation of HLA Class I Antigen-Processing Molecules in Malignant Melanoma
resolves10.1007/s002620050589
Selective MHC expression in tumours modulates adaptive and innate antitumour responses
resolves10.4049/jimmunol.163.8.4224
Deficiency of Transporter for Antigen Presentation (TAP) in Tumor Cells Allows Evasion of Immune Surveillance and Increases Tumorigenesis
resolves10.1046/j.1440-1746.2003.02921.x
Impaired expression of proteasome subunits and human leukocyte antigens class I in human colon cancer cells
resolves10.1007/s00262-003-0483-7
Immunological inhibition of carcinogenesis
resolves10.1002/ijc.10557
Extremely potent, rapid and costimulation‐independent cytotoxic T‐cell response against lymphoma cells catalyzed by a single‐chain bispecific antibody
resolves10.1182/blood.V95.6.2098
A recombinant bispecific single-chain antibody, CD19 × CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes
resolves10.1038/sj.leu.2402890
Efficient elimination of chronic lymphocytic leukaemia B cells by autologous T cells with a bispecific anti-CD19/anti-CD3 single-chain antibody construct
resolves10.4049/jimmunol.170.8.4397
T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct
resolves10.1002/ijc.2910230206
Characterization of a leukemic cell line of the pre‐B phenotype
resolves10.1016/S1074-7613(01)00234-5
The Immunological Synapse of CTL Contains a Secretory Domain and Membrane Bridges
resolves10.4049/jimmunol.155.4.1903
Identification of heavy chain residues in a humanized anti-CD3 antibody important for efficient antigen binding and T cell activation
resolves10.1002/ijc.2910620315
Engineering high affinity humanized anti‐p185<sup>HER2</sup>/anti‐CD3 bispecific F(ab′)2 for efficient lysis of p185<sup>HER2</sup> overexpressing tumor cells
resolves10.1002/ijc.11056
Efficient tumor cell lysis by autologous, tumor‐resident T lymphocytes in primary ovarian cancer samples by an EP‐CAM‐/CD3‐bispecific antibody
resolves10.1038/sj.leu.2403264
A novel recombinant bispecific single-chain antibody, bscWue-1 × CD3, induces T-cell-mediated cytotoxicity towards human multiple myeloma cells
resolves10.1007/s002620050431
Construction and biological activity of a recombinant bispecific single-chain antibody designed for therapy of minimal residual colorectal cancer
resolves10.1016/j.tibtech.2004.03.006
A revival of bispecific antibodies
resolves10.1016/S0145-2126(03)00180-2
Prognostic relevance of immunophenotyping in 379 patients with acute myeloid leukemia
resolves10.1126/science.286.5441.952
TCR-Mediated Internalization of Peptide-MHC Complexes Acquired by T Cells
The 1 reference without a DOI — listed, not checked
no DOI — not checkedBispecific antibodies for polyclonal T‐cell engagement
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