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In silico investigation of nonsynonymous single nucleotide polymorphisms in<i>BCL2</i>apoptosis regulator gene to design novel protein‐based drugs against cancer

https://doi.org/10.1002/jcb.30330
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52/52 checkable references clean · checked 2026-07-22

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 52 checked references that resolve
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Caspases in the Developing Central Nervous System: Apoptosis and Beyond
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A Catalog of Neutral and Deleterious Polymorphism in Yeast
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resolves10.1093/carcin/bgm172
Single-nucleotide polymorphisms at the TP53-binding or responsive promoter regions of BAX and BCL2 genes and risk of squamous cell carcinoma of the head and neck
resolves10.1016/j.leukres.2015.08.014
BCL2 gene polymorphisms and splicing variants in chronic myeloid leukemia
resolves10.1101/cshperspect.a008722
Multiple Functions of BCL-2 Family Proteins
resolves10.1007/s00726-011-1108-7
In silico investigation of molecular mechanism of laminopathy caused by a point mutation (R482W) in lamin A/C protein
resolves10.1016/j.compbiolchem.2022.107669
In-silico analysis of non-synonymous single nucleotide polymorphisms in human β-defensin type 1 gene reveals their impact on protein-ligand binding sites
resolves10.7554/eLife.20352
Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer
resolves10.3390/cells9051287
Inhibition of Anti-Apoptotic Bcl-2 Proteins in Preclinical and Clinical Studies: Current Overview in Cancer
resolves10.1016/S0014-5793(04)00059-6
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resolves10.1093/nar/29.1.308
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resolves10.1093/bioinformatics/19.1.163
ConSurf: Identification of Functional Regions in Proteins by Surface-Mapping of Phylogenetic Information
resolves10.1021/acsomega.0c01295
Novel Approach for Characterizing Propofol Binding Affinities to Serum Albumins from Different Species
resolves10.1093/nar/gkaa275
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resolves10.1038/s41467-020-19669-x
Inferring the molecular and phenotypic impact of amino acid variants with MutPred2
resolves10.1186/gb-2008-9-s1-s4
GeneMANIA: a real-time multiple association network integration algorithm for predicting gene function
resolves10.1073/pnas.81.1.140
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resolves10.3389/fchem.2021.736509
Scaffold Searching of FDA and EMA-Approved Drugs Identifies Lead Candidates for Drug Repurposing in Alzheimer’s Disease
resolves10.1021/acs.jctc.7b00125
The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design
resolves10.1098/rsif.2014.0419
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resolves10.1038/sj.onc.1202490
Bcl-2 regulates a caspase-3/caspase-2 apoptotic cascade in cytosolic extracts
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Multidrug resistance protein P-gp interaction with nanoparticles (fullerenes and carbon nanotube) to assess their drug delivery potential: a theoretical molecular docking study
resolves10.1007/s00204-014-1448-7
The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update
resolves10.1371/journal.pcbi.1007485
Alterations of the interactome of Bcl-2 proteins in breast cancer at the transcriptional, mutational and structural level
resolves10.1073/pnas.1015328108
Arginine methylation of BCL-2 antagonist of cell death (BAD) counteracts its phosphorylation and inactivation by Akt
resolves10.1167/iovs.63.3.2
The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells
resolves10.1073/pnas.0809414106
Mechanism of Bcl-2 and Bcl-X <sub>L</sub> inhibition of NLRP1 inflammasome: Loop domain-dependent suppression of ATP binding and oligomerization
resolves10.2174/138161206779010495
Role of Alterations in the Apoptotic Machinery in Sensitivity of Cancer Cells to Treatment
resolves10.1007/s12032-021-01513-x
Computational study on novel natural inhibitors targeting BCL2
resolves10.1016/j.jmgm.2017.11.011
Exploring the selectivity of inhibitor complexes with Bcl-2 and Bcl-XL: A molecular dynamics simulation approach
resolves10.1002/mgg3.910
Docking‐based approach for identification of mutations that disrupt binding between Bcl‐2 and Bax proteins: Inducing apoptosis in cancer cells
The 2 references without a DOI — listed, not checked
no DOI — not checkedBCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma
no DOI — not checkedPredicting functional effect of human missense mutations using PolyPhen‐2
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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