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β‐catenin‐controlled tubular cell‐derived exosomes play a key role in fibroblast activation via the OPN‐CD44 axis

https://doi.org/10.1002/jev2.12203
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51/51 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 51 checked references that resolve
resolves10.3390/ijms21228490
Stimulation of THP-1 Macrophages with LPS Increased the Production of Osteopontin-Encapsulating Exosome
resolves10.7150/thno.54550
Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury
resolves10.1074/jbc.M211074200
Rho-dependent Rho Kinase Activation Increases CD44 Surface Expression and Bone Resorption in Osteoclasts
resolves10.1186/s13045-018-0605-5
The biology and role of CD44 in cancer progression: therapeutic implications
resolves10.2337/dbi21-0015
A Novel Mechanism of Regulation for Exosome Secretion in the Diabetic Kidney
resolves10.1016/j.matbio.2018.02.006
Renal fibrosis: Primacy of the proximal tubule
resolves10.1016/j.kint.2016.08.025
Progression of chronic kidney disease: too much cellular talk causes damage
resolves10.1038/nm.3901
Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease
resolves10.1016/j.yexcr.2020.112007
Injured tubular epithelial cells activate fibroblasts to promote kidney fibrosis through miR-150-containing exosomes
resolves10.3390/biomedicines9081006
Both Full-Length and Protease-Cleaved Products of Osteopontin Are Elevated in Infectious Diseases
resolves10.7150/thno.21945
Exosome Theranostics: Biology and Translational Medicine
resolves10.1016/j.kint.2017.06.030
AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms
resolves10.1016/j.bone.2017.11.002
Osteopontin as a novel substrate for the proprotein convertase 5/6 (PCSK5) in bone
resolves10.1186/s13287-021-02266-0
Stem/progenitor cell in kidney: characteristics, homing, coordination, and maintenance
resolves10.1146/annurev-physiol-022516-034227
Mechanisms of Renal Fibrosis
resolves10.18632/aging.102811
Adiponectin in renal fibrosis
resolves10.1038/s41419-019-1605-2
The role of extracellular vesicles in renal fibrosis
resolves10.1007/s00011-018-1200-5
The role of osteopontin in kidney diseases
resolves10.1038/nm.3762
Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development
resolves10.1172/JCI123360
An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion
resolves10.1016/j.matbio.2018.05.007
The CD44-HA axis and inflammation in atherosclerosis: A temporal perspective
resolves10.1016/j.scr.2020.101799
The primary cilium directs osteopontin-induced migration of mesenchymal stem cells by regulating CD44 signaling and Cdc42 activation
resolves10.1016/j.kint.2018.09.013
HIF-1α inducing exosomal microRNA-23a expression mediates the cross-talk between tubular epithelial cells and macrophages in tubulointerstitial inflammation
resolves10.1016/j.lfs.2020.117328
Osteopontin induces atrial fibrosis by activating Akt/GSK-3β/β-catenin pathway and suppressing autophagy
resolves10.3389/fcell.2021.681790
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice
resolves10.1016/j.kint.2019.11.026
Tubule-derived exosomes play a central role in fibroblast activation and kidney fibrosis
resolves10.1038/nrneph.2011.149
Cellular and molecular mechanisms of renal fibrosis
resolves10.1681/ASN.2017050523
Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation
resolves10.1038/s41418-019-0349-y
Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury
resolves10.1111/acel.13004
Wnt/β‐catenin/RAS signaling mediates age‐related renal fibrosis and is associated with mitochondrial dysfunction
resolves10.1016/j.addr.2017.12.019
Targeting renal fibrosis: Mechanisms and drug delivery systems
resolves10.1097/WNR.0b013e328355380e
Osteopontin is upregulated after mechanical brain injury and stimulates neurite growth from hippocampal neurons through β1 integrin and CD44
resolves10.1002/path.4049
Epithelial–mesenchymal crosstalk alteration in kidney fibrosis
resolves10.1038/s41419-018-1157-x
Renal tubular epithelial cells: the neglected mediator of tubulointerstitial fibrosis after injury
resolves10.1159/000446336
Signaling Crosstalk between Tubular Epithelial Cells and Interstitial Fibroblasts after Kidney Injury
resolves10.1126/sciadv.aaz0748
Extracellular vesicle–encapsulated IL-10 as novel nanotherapeutics against ischemic AKI
resolves10.3390/ijms21155568
Osteopontin: The Molecular Bridge between Fat and Cardiac–Renal Disorders
resolves10.1080/0886022X.2020.1811121
Effect of hypoxia-inducible factor-prolyl hydroxylase inhibitors on anemia in patients with CKD: a meta-analysis of randomized controlled trials including 2804 patients
resolves10.1016/j.devcel.2019.04.011
Exosome-Mediated Metastasis: Communication from a Distance
resolves10.1016/j.taap.2011.09.024
Kaempferol regulates OPN–CD44 pathway to inhibit the atherogenesis of apolipoprotein E deficient mice
resolves10.1681/ASN.2015040449
Sustained Activation of Wnt/β-Catenin Signaling Drives AKI to CKD Progression
resolves10.3389/fphar.2020.601325
Cellular Senescence in Kidney Fibrosis: Pathologic Significance and Therapeutic Strategies
resolves10.1038/nm.2144
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
resolves10.1159/000477310
Capn4 Enhances Osteopontin Expression through Activation of the Wnt/β-Catenin Pathway to Promote Epithelial Ovarian Carcinoma Metastasis
resolves10.1038/sj.ki.5000357
Osteopontin regulates renal apoptosis and interstitial fibrosis in neonatal chronic unilateral ureteral obstruction
resolves10.1038/ki.2012.173
Tubule-specific ablation of endogenous β-catenin aggravates acute kidney injury in mice
resolves10.1038/nrneph.2015.215
Understanding the mechanisms of kidney fibrosis
resolves10.1038/srep01878
Kidney tubular β-catenin signaling controls interstitial fibroblast fate via epithelial-mesenchymal communication
resolves10.1681/ASN.2013101067
Mutual Antagonism of Wilms’ Tumor 1 and β-Catenin Dictates Podocyte Health and Disease
resolves10.1016/j.kint.2020.09.025
Cannabinoid receptor type 2 promotes kidney fibrosis through orchestrating β-catenin signaling
The 3 references without a DOI — listed, not checked
no DOI — not checkedβ‐catenin ablation exacerbates polycystic kidney disease progression
no DOI — not checkedThe impact of CKD identification in large countries: The burden of illness
no DOI — not checkedOPN ‐Revisited
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