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Effects of Solution Conditions, Processing Parameters, and Container Materials on Aggregation of a Monoclonal Antibody during Freeze-Thawing
20/20 checkable references clean · checked 2026-07-24
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 20 checked references that resolve
resolves10.1021/bi00320a004
Mechanism of protein salting in and salting out by divalent cation salts: balance between hydration and salt binding
resolves10.1023/A:1011082911917
Effect of Initial Buffer Composition on pH Changes During Far-From-Equilibrium Freezing of Sodium Phosphate Buffer Solutions
resolves10.1002/jps.1078
Lyophilization‐induced protein denaturation in phosphate buffer systems: Monomeric and tetrameric β‐galactosidase
resolves10.1021/js980383n
Effects of buffer composition and processing conditions on aggregation of bovine IgG during freeze-drying
resolves10.1021/js980126i
Effect of tween 20 on freeze-thawing- and agitation-induced aggregation of recombinant human factor XIII
resolves10.1073/pnas.88.21.9377
Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces.
resolves10.1023/A:1025771421906
Physical Stability of Proteins in Aqueous Solution: Mechanism and Driving Forces in Nonnative Protein Aggregation
resolves10.1002/(SICI)1097-0290(19990420)63:2<166::AID-BIT5>3.0.CO;2-H
Protein formulation and lyophilization cycle design: Prevention of damage due to freeze-concentration induced phase separation
resolves10.1006/abbi.2000.2088
Protein Denaturation during Freezing and Thawing in Phosphate Buffer Systems: Monomeric and Tetrameric β-Galactosidase
resolves10.1002/jps.10439
Derivative Absorbance Spectroscopy and Protein Phase Diagrams as Tools for Comprehensive Protein Characterization: A bGCSF Case Study
resolves10.1006/abio.1994.1499
Simultaneous Monitoring of the Environment of Tryptophan, Tyrosine, and Phenylalanine Residues in Proteins by Near-Ultraviolet Second-Derivative Spectroscopy
resolves10.1002/bit.10612
Effect of freezing and thawing rates on denaturation of proteins in aqueous solutions
resolves10.1023/A:1016270103863
Surface Denaturation at Solid-Void Interface—A Possible Pathway by Which Opalescent Participates Form During the Storage of Lyophilized Tissue-Type Plasminogen Activator at High Temperatures
resolves10.1002/jps.10334
Effects of annealing lyophilized and spray‐lyophilized formulations of recombinant human interferon‐γ
resolves10.1002/jps.10135
Surface adsorption of recombinant human interferon‐γ in lyophilized and spray‐lyophilized formulations
resolves10.1021/js960080y
Surface-Induced Denaturation of Proteins during Freezing and its Inhibition by Surfactants
resolves10.1016/S0006-3495(96)79640-6
Proteins in frozen solutions: evidence of ice-induced partial unfolding
resolves10.1006/abbi.1996.0337
Polymers Protect Lactate Dehydrogenase during Freeze-Drying by Inhibiting Dissociation in the Frozen State
resolves10.1016/S0304-4165(01)00101-5
Adsorption of IgG onto hydrophobic teflon. Differences between the Fab and Fc domains
The 3 references without a DOI — listed, not checked
no DOI — not checkedPhysical damage to proteins during freezing, drying and rehydration
no DOI — not checkedThe properties of aqueous solutions at subzero temperatures
no DOI — not checkedInteractions of stabilizing additives with proteins during freeze-thawing and freeze-drying
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