Reference health
A review on the recent advances in HPLC, UHPLC and UPLC analyses of naturally occurring cannabinoids (2010–2019)
105/105 checkable references clean · checked 2026-07-22
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
7 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 105 checked references that resolve
resolves10.1002/pca.2886
Gas chromatographic analysis of naturally occurring cannabinoids: A review of literature published during the past decade
resolves10.1007/s00216-014-8177-x
Identification and quantification of cannabinoids in Cannabis sativa L. plants by high performance liquid chromatography-mass spectrometry
resolves10.1002/dta.1753
Quantification of six cannabinoids and metabolites in oral fluid by liquid chromatography‐tandem mass spectrometry
resolves10.1016/j.forsciint.2014.01.004
Simultaneous determination of Δ9-tetrahydrocannabinol, cannabidiol, cannabinol and 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in hair using liquid chromatography–tandem mass spectrometry
resolves10.1007/s00216-012-6501-x
Simultaneous and sensitive LC–MS/MS determination of tetrahydrocannabinol and metabolites in human plasma
resolves10.1016/j.aca.2018.06.016
Recent advances in LC-MS/MS methods to determine endocannabinoids in biological samples: Application in neurodegenerative diseases
resolves10.1016/j.microc.2014.05.015
An improved method for the determination of ∆9-tetrahydrocannabinol, cannabinol and cannabidiol in hair by liquid chromatography–tandem mass spectrometry
resolves10.1002/rcm.8242
A rapid method to determine nine natural cannabinoids in beverages and food derived from
<scp>
<i>Cannabis sativa</i>
</scp>
by liquid chromatography coupled to tandem mass spectrometry on a QTRAP 4000
resolves10.1002/jms.3152
Development and validation of an LC‐MS/MS method for quantification of Δ9‐tetrahydrocannabinolic acid A (THCA‐A), THC, CBN and CBD in hair
resolves10.1016/j.chroma.2013.05.072
Micro extraction by packed sorbent coupled to liquid chromatography tandem mass spectrometry for the rapid and sensitive determination of cannabinoids in oral fluids
resolves10.1093/jat/bkw063
An Efficient, Robust Method for the Determination of Cannabinoids in Whole Blood by LC–MS-MS
resolves10.1016/B978-0-12-800874-4.00019-2
Applications of High Performance Liquid Chromatography in the Analysis of Herbal Products
resolves10.1002/dta.2199
Determination of cannabinoid and synthetic cannabinoid metabolites in wastewater by liquid–liquid extraction and ultra‐high performance supercritical fluid chromatography‐tandem mass spectrometry
resolves10.1089/can.2016.0020
Decarboxylation Study of Acidic Cannabinoids: A Novel Approach Using Ultra-High-Performance Supercritical Fluid Chromatography/Photodiode Array-Mass Spectrometry
resolves10.1111/1556-4029.13341
Quantitative Determination of Cannabinoids in Cannabis and Cannabis Products Using Ultra‐High‐Performance Supercritical Fluid Chromatography and Diode Array/Mass Spectrometric Detection
resolves10.3390/molecules23092359
Analysis of Contact Traces of Cannabis by In-Tube Solid-Phase Microextraction Coupled to Nanoliquid Chromatography
resolves10.5740/jaoacint.15-095
Determination of 11 Cannabinoids in Biomass and Extracts of Different Varieties of Cannabis Using High-Performance Liquid Chromatography
resolves10.1016/j.supflu.2019.01.020
Extraction, isolation and purification of tetrahydrocannabinol from the Cannabis sativa L. plant using supercritical fluid extraction and solid phase extraction
resolves10.1016/j.talanta.2015.02.040
1 H NMR and HPLC/DAD for Cannabis sativa L. chemotype distinction, extract profiling and specification
resolves10.1002/pca.2722
A Metabolomic Approach Applied to a Liquid Chromatography Coupled to High‐Resolution Tandem Mass Spectrometry Method (HPLC‐ESI‐HRMS/MS): Towards the Comprehensive Evaluation of the Chemical Composition of Cannabis Medicinal Extracts
resolves10.1016/j.talanta.2018.09.012
Quantification of THC in Cannabis plants by fast-HPLC-DAD: A promising method for routine analyses
resolves10.1186/s40543-018-0159-8
Determination of cannabinoids in Cannabis sativa L. samples for recreational, medical, and forensic purposes by reversed-phase liquid chromatography-ultraviolet detection
resolves10.3390/molecules24112113
Fast Detection of 10 Cannabinoids by RP-HPLC-UV Method in Cannabis sativa L.
resolves10.3390/molecules23102639
New Methods for the Comprehensive Analysis of Bioactive Compounds in Cannabis sativa L. (hemp)
resolves10.1016/j.jpba.2017.05.049
Development of a new extraction technique and HPLC method for the analysis of non-psychoactive cannabinoids in fibre-type Cannabis sativa L. (hemp)
resolves10.1016/j.jpba.2017.11.073
Comprehensive quality evaluation of medical Cannabis sativa L. inflorescence and macerated oils based on HS-SPME coupled to GC–MS and LC-HRMS (q-exactive orbitrap®) approach
resolves10.1016/j.jchromb.2019.01.027
Development of a validated method for the qualitative and quantitative analysis of cannabinoids in plant biomass and medicinal cannabis resin extracts obtained by super-critical fluid extraction
resolves10.1016/j.jpba.2018.03.059
Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts
resolves10.1055/s-0043-124873
Quantitative Determination of Δ9-THC, CBG, CBD, Their Acid Precursors and Five Other Neutral Cannabinoids by UHPLC-UV-MS
resolves10.1055/s-0044-100798
Detection and Quantification of Cannabinoids in Extracts of Cannabis sativa Roots Using LC-MS/MS
resolves10.1016/j.foodchem.2017.01.128
Analysis of cannabinoids by liquid chromatography–mass spectrometry in milk, liver and hemp seed to ensure food safety
resolves10.3390/molecules23051230
Quality Traits of “Cannabidiol Oils”: Cannabinoids Content, Terpene Fingerprint and Oxidation Stability of European Commercially Available Preparations
resolves10.1016/j.jpba.2019.01.032
Analytical quality by design: Development and control strategy for a LC method to evaluate the cannabinoids content in cannabis olive oil extracts
resolves10.2174/1389201019666171129175655
Therapeutic Use of Δ9-THC and Cannabidiol: Evaluation of a New Extraction Procedure for the Preparation of Cannabis-based Olive Oil
resolves10.1371/journal.pone.0196396
A reliable and validated LC-MS/MS method for the simultaneous quantification of 4 cannabinoids in 40 consumer products
resolves10.1016/j.jpba.2017.07.021
Qualitative and quantitative measurement of cannabinoids in cannabis using modified HPLC/DAD method
resolves10.1016/j.forsciint.2019.03.046
Quantitative determination of CBD and THC and their acid precursors in confiscated cannabis samples by HPLC-DAD
resolves10.1021/acsmedchemlett.8b00571
Cannabinoids from <i>Cannabis sativa</i> L.: A New Tool Based on HPLC–DAD–MS/MS for a Rational Use in Medicinal Chemistry
resolves10.1016/j.forsciint.2018.05.033
Commercial cannabis consumer products part 2: HPLC-DAD quantitative analysis of cannabis cannabinoids
resolves10.3390/scipharm84030567
Quality Control of Traditional Cannabis Tinctures: Pattern, Markers, and Stability
resolves10.1002/dta.2062
Determination of cannabinoids in hemp nut products in Taiwan by HPLC‐MS/MS coupled with chemometric analysis: quality evaluation and a pilot human study
resolves10.1016/j.jpba.2016.05.033
Medicinal cannabis: Principal cannabinoids concentration and their stability evaluated by a high performance liquid chromatography coupled to diode array and quadrupole time of flight mass spectrometry method
resolves10.1111/jphp.12845
Cannabinoids concentration variability in cannabis olive oil galenic preparations
resolves10.1515/cclm-2016-1060
Evaluation of cannabinoids concentration and stability in standardized preparations of cannabis tea and cannabis oil by ultra-high performance liquid chromatography tandem mass spectrometry
resolves10.1016/j.ijms.2016.10.018
Isomeric separation of cannabinoids by UPLC combined with ionic mobility mass spectrometry (TWIM-MS)—Part I
resolves10.1007/s00216-011-5197-7
Direct quantification of cannabinoids and cannabinoid glucuronides in whole blood by liquid chromatography–tandem mass spectrometry
resolves10.1016/j.chroma.2016.05.024
Quantification of cannabinoids and their free and glucuronide metabolites in whole blood by disposable pipette extraction and liquid chromatography-tandem mass spectrometry
resolves10.1007/s00216-011-4708-x
On-line SPE LC-MS/MS for the quantification of Δ9-tetrahydrocannabinol (THC) and its two major metabolites in human peripheral blood by liquid chromatography tandem mass spectrometry
resolves10.1016/j.chroma.2012.11.030
Dried blood spots: Liquid chromatography–mass spectrometry analysis of Δ9-tetrahydrocannabinol and its main metabolites
resolves10.1016/j.jchromb.2012.08.006
Fast liquid chromatography/tandem mass spectrometry determination of cannabinoids in micro volume blood samples after dabsyl derivatization
resolves10.1016/j.forc.2017.12.007
LC–MS/MS screening strategy for cannabinoids, opiates, amphetamines, cocaine, benzodiazepines and methadone in human serum, urine and post-mortem blood as an effective alternative to immunoassay based methods applied in forensic toxicology for preliminary examination
resolves10.1097/FTD.0000000000000583
Simultaneous Quantification of 13 Cannabinoids and Metabolites in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry in Adult Epilepsy Patients
resolves10.1097/FTD.0000000000000427
An Atmospheric Pressure Chemical Ionization MS/MS Assay Using Online Extraction for the Analysis of 11 Cannabinoids and Metabolites in Human Plasma and Urine
resolves10.1002/dta.1998
Simultaneous quantification of major cannabinoids and metabolites in human urine and plasma by HPLC‐MS/MS and enzyme‐alkaline hydrolysis
resolves10.1007/s11419-016-0344-7
Simple protein precipitation-based analysis of Δ9-tetrahydrocannabinol and its metabolites in human serum by liquid chromatography–tandem mass spectrometry
resolves10.1080/00085030.2017.1303255
An ultra-high-pressure liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the detection of cannabinoids in whole blood using solid phase extraction
resolves10.1093/jat/bkx030
Sensitive Determination of Cannabinoids in Whole Blood by LC–MS-MS After Rapid Removal of Phospholipids by Filtration
resolves10.1002/rcm.5165
Qualitative and quantitative analysis of THC, 11‐hydroxy‐THC and 11‐nor‐9‐carboxy‐THC in whole blood by ultra‐performance liquid chromatography/tandem mass spectrometry
resolves10.1016/j.jchromb.2019.03.002
Development and validation of an assay to measure cannabidiol and Δ9-tetrahydrocannabinol in human EDTA plasma by UHPLC-MS/MS
resolves10.1016/j.jchromb.2017.02.007
Ultra-high performance liquid chromatography tandem mass-spectrometry for simple and simultaneous quantification of cannabinoids
resolves10.1093/jat/bkz023
Quantitation of Cannabinoids in Breath Samples Using a Novel Derivatization LC–MS/MS Assay with Ultra-High Sensitivity
resolves10.1016/j.chroma.2015.12.011
Water-compatible imprinted pills for sensitive determination of cannabinoids in urine and oral fluid
resolves10.1016/j.chroma.2013.04.071
Simultaneous quantification of Δ9-tetrahydrocannabinol, 11-nor-9-carboxy-tetrahydrocannabinol, cannabidiol and cannabinol in oral fluid by microflow-liquid chromatography–high resolution mass spectrometry
resolves10.1007/s00216-013-7027-6
11-Nor-9-carboxy-∆9-tetrahydrocannabinol quantification in human oral fluid by liquid chromatography–tandem mass spectrometry
resolves10.1007/s11419-012-0168-z
Analysis of cannabinoids in oral fluid by liquid chromatography–tandem mass spectrometry
resolves10.1016/j.forsciint.2012.08.048
Prescription and illicit psychoactive drugs in oral fluid—LC–MS/MS method development and analysis of samples from Brazilian drivers
resolves10.1002/dta.1739
Significant enhancement of 11‐Hydroxy‐THC detection by formation of picolinic acid esters and application of liquid chromatography/multi stage mass spectrometry (LC‐MS<sup>3</sup>): Application to hair and oral fluid analysis
resolves10.1016/j.jpba.2019.02.039
Dilute and shoot ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC–MS/MS) analysis of psychoactive drugs in oral fluid
resolves10.1007/s00216-016-9458-3
Ultra-rapid targeted analysis of 40 drugs of abuse in oral fluid by LC-MS/MS using carbon-13 isotopes of methamphetamine and MDMA to reduce detector saturation
resolves10.1016/j.cca.2019.01.002
Validation of a liquid chromatography-tandem mass spectrometry method for analyzing cannabinoids in oral fluid
resolves10.1021/acsomega.6b00253
Sensitive Quantification of Cannabinoids in Milk by Alkaline Saponification–Solid Phase Extraction Combined with Isotope Dilution UPLC–MS/MS
resolves10.1016/j.microc.2017.03.050
High-throughput screening for drugs of abuse and pharmaceutical drugs in hair by liquid-chromatography-high resolution mass spectrometry (LC-HRMS)
resolves10.1016/j.chroma.2015.06.021
Pressurized liquid extraction for the determination of cannabinoids and metabolites in hair: Detection of cut-off values by high performance liquid chromatography–high resolution tandem mass spectrometry
resolves10.1016/j.jchromb.2011.05.034
Screening and quantitation of multiclass drugs of abuse and pharmaceuticals in hair by fast liquid chromatography electrospray time-of-flight mass spectrometry
resolves10.1002/dta.1692
Cannabinoid findings in children hair – what do they really tell us? An assessment in the light of three different analytical methods with focus on interpretation of Δ9‐tetrahydrocannabinolic acid A concentrations
resolves10.1007/s00216-016-0046-3
Cannabinoids assessment in plasma and urine by high performance liquid chromatography–tandem mass spectrometry after molecularly imprinted polymer microsolid-phase extraction
resolves10.1016/j.cca.2012.06.034
Simultaneous quantification of free and glucuronidated cannabinoids in human urine by liquid chromatography tandem mass spectrometry
resolves10.1556/1326.2017.29.2.09
Fast confirmation for marijuana metabolite: THC-COOH, ultra-fast LC—MS/MS run time, and application to routine samples
resolves10.4155/bio-2016-0281
Rapid Quantification of Free and Glucuronidated Thccooh in Urine Using Coated Well Plates and LC–MS/MS Analysis
resolves10.1016/j.jpba.2013.12.035
A μ-SPE procedure for the determination of cannabinoids and their metabolites in urine by LC–MS/MS
resolves10.1016/j.chroma.2013.06.028
Rapid screening of drugs of abuse in human urine by high-performance liquid chromatography coupled with high resolution and high mass accuracy hybrid linear ion trap-Orbitrap mass spectrometry
resolves10.1002/jssc.201100132
Analysis of abuse drugs in urine using surfactant‐assisted dispersive liquid–liquid microextraction
resolves10.1016/j.jpba.2018.08.045
Developing a rapid semi-automated sample preparation with alkaline hydrolysis in a 96-well plate for quantification of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in urine samples by UHPLC-MS/MS
resolves10.1016/j.jchromb.2016.08.002
Simultaneous determination of major phytocannabinoids, their main metabolites, and common synthetic cannabinoids in urine samples by LC⿿MS/MS
resolves10.1007/s00216-016-9765-8
Simultaneous quantification of 11 cannabinoids and metabolites in human urine by liquid chromatography tandem mass spectrometry using WAX-S tips
resolves10.1016/j.chroma.2017.03.066
Development and validation of a liquid chromatography tandem mass spectrometry method for the determination of cannabinoids and phase I and II metabolites in meconium
resolves10.1016/j.forsciint.2011.04.010
A preliminary investigation on the distribution of cannabinoids in man
resolves10.1016/j.forsciint.2018.07.004
Determination of drugs of abuse and pharmaceuticals in skeletal tissue by UHPLC–MS/MS
resolves10.1016/j.jpba.2017.11.054
Development of a simple and sensitive liquid chromatography triple quadrupole mass spectrometry (LC–MS/MS) method for the determination of cannabidiol (CBD), Δ 9 -tetrahydrocannabinol (THC) and its metabolites in rat whole blood after oral administration of a single high dose of CBD
resolves10.1016/j.jpba.2018.07.004
Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant
resolves10.1016/j.jpba.2015.05.019
Development of a simple and sensitive HPLC–UV method for the simultaneous determination of cannabidiol and Δ9-tetrahydrocannabinol in rat plasma
resolves10.1093/jat/34.8.516
Disposition of Cannabichromene, Cannabidiol, and 9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High-Performance Liquid Chromatography-Tandem Mass Spectrometry
resolves10.1021/acs.analchem.7b01094
Development of a Rapid LC-MS/MS Method for the Quantification of Cannabidiol, Cannabidivarin, Δ<sup>9</sup>-Tetrahydrocannabivarin, and Cannabigerol in Mouse Peripheral Tissues
resolves10.1016/j.chroma.2019.03.034
Development of a new method for the analysis of cannabinoids in honey by means of high-performance liquid chromatography coupled with electrospray ionisation-tandem mass spectrometry detection
resolves10.1093/jat/bkw027
Simultaneous Analysis of Cannabinoid and Synthetic Cannabinoids in Dietary Supplements Using UPLC with UV and UPLC–MS-MS
resolves10.1016/j.chroma.2013.10.078
Illicit and abused drugs in sewage sludge: Method optimization and occurrence
resolves10.1016/j.chroma.2016.07.062
Analysis of psychoactive substances in water by information dependent acquisition on a hybrid quadrupole time-of-flight mass spectrometer
resolves10.1080/20961790.2016.1270812
Quantitative analysis of opioids and cannabinoids in wastewater samples
The 7 references without a DOI — listed, not checked
no DOI — not checkedGuest editorial: UPLC in phytochemical analysis
no DOI — not checkedAnalysis of isomeric cannabinoid standards and Cannabis products by UPLC‐ESI‐TWIM‐MS: a comparison with GC‐MS and GC x GC‐QMS
no DOI — not checkedDetermination of three kinds of cannabinoids in cannabis using ultra high performance liquid chromatography‐tandem mass spectrometry and analysis of phenotype of cannabis
no DOI — not checkedMolecularly imprinted polymer for selective determination of delta(9)‐tetrahydrocannabinol and 11‐nor‐delta(9)‐tetrahydrocannabinol carboxylic acid using LC‐MS/MS in urine and oral fluid
no DOI — not checkedComparative evaluation of drug deposition in hair samples collected from different anatomical body sites
no DOI — not checkedHair‐based rapid analyses for multiple drugs in forensics and doping: application of dynamic multiple reaction monitoring with LC‐MS/MS
no DOI — not checkedPreconcentration and analysis of cannabinoid compounds (THC‐9, CBN, CBD) in urine samples by IL‐ISFME/D‐mu‐SPE/HPLC‐DAD
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