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Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection

https://doi.org/10.1002/tox.20640
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37/37 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 37 checked references that resolve
resolves10.1016/0165-1218(85)90069-2
Is there a continuing role for the intraperitoneal injection route of exposure in short-term rodent genotoxicity assays?
resolves10.1002/em.2850100414
Choice of route of exposure in mammalian genotoxicity experiments
resolves10.1002/em.20539
Genotoxicity of a freshwater cyanotoxin, cylindrospermopsin, in two human cell lines: Caco‐2 and HepaRG
resolves10.1016/0041-0101(83)90151-4
An outbreak of hepato-enteritis (the Palm Island mystery disease) possibly caused by algal intoxication
resolves10.1016/j.mrgentox.2006.08.011
Fourth International Workgroup on Genotoxicity testing: Results of the in vivo Comet assay workgroup
resolves10.1385/MB:26:3:249
The Comet Assay for DNA Damage and Repair: Principles, Applications, and Limitations
resolves10.1016/j.cellbi.2004.04.003
The comet assay differentiates efficiently and rapidly between genotoxins and cytotoxins in quiescent cells
resolves10.1002/tox.1024
Preliminary evidence for in vivo tumour initiation by oral administration of extracts of the blue‐green alga <i>Cylindrospermopsis raciborskii</i> containing the toxin cylindrospermopsin
resolves10.1002/tox.10136
Cell alterations but no DNA strand breaks induced <i>in vitro</i> by cylindrospermopsin in CHO K1 cells
resolves10.1002/tox.10121
Cylindrospermopsin‐induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes
resolves10.1016/0041-0101(94)90023-X
Isolation of cylindrospermopsin from a cyanobacterium Umezakia natans and its screening method
resolves10.1128/aem.50.5.1292-1295.1985
Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju isolated from a domestic water supply reservoir
resolves10.1016/0165-1218(89)90081-5
Difference between intraperitoneal and oral gavage application in the micronucleus test
resolves10.1002/tox.10104
Oral toxicity of the cyanobacterial toxin cylindrospermopsin in male Swiss albino mice: Determination of no observed adverse effect level for deriving a drinking water guideline value
resolves10.1016/S1383-5718(00)00144-3
Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin
resolves10.1080/15287390590925465
Cylindrospermopsin Genotoxicity and Cytotoxicity: Role Of Cytochrome P-450 and Oxidative Stress
resolves10.1046/j.1529-8817.2001.01075.x
FIRST REPORT OF THE CYANOTOXINS CYLINDROSPERMOPSIN AND DEOXYCYLINDROSPERMOPSIN FROM <i>RAPHIDIOPSIS CURVATA</i> (CYANOBACTERIA)
resolves10.1016/j.mrgentox.2007.02.010
In vivo Comet assay on isolated kidney cells to distinguish genotoxic carcinogens from epigenetic carcinogens or cytotoxic compounds
resolves10.1002/tox.10008
Distribution of <sup>14</sup>C cylindrospermopsin <i>in vivo</i> in the mouse
resolves10.1016/S0041-0101(01)00243-4
Hepatic xenobiotic metabolism of cylindrospermopsin in vivo in the mouse
resolves10.1021/ja00046a067
Cylindrospermopsin: a potent hepatotoxin from the blue-green alga Cylindrospermopsis raciborskii
resolves10.1016/S1383-5718(02)00061-X
Collaborative validation study of the in vivo micronucleus test using mouse colonic epithelial cells
resolves10.1016/j.toxicon.2005.10.013
First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes
resolves10.1016/S0006-2952(94)00466-8
Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes
resolves10.1016/S1383-5718(98)00002-3
Organ-specific genotoxicity of the potent rodent colon carcinogen 1,2-dimethylhydrazine and three hydrazine derivatives: difference between intraperitoneal and oral administration
resolves10.1002/tox.1051
Identification of genes implicated in toxin production in the cyanobacterium <i>Cylindrospermopsis raciborskii</i>
resolves10.1002/(SICI)1522-7278(199902)14:1<135::AID-TOX17>3.0.CO;2-L
The oral toxicity for mice of the tropical cyanobacteriumCylindrospermopsis raciborskii (Woloszynska)
resolves10.1016/j.hal.2006.07.001
First evidence for the production of cylindrospermopsin and deoxy-cylindrospermopsin by the freshwater benthic cyanobacterium, Lyngbya wollei (Farlow ex Gomont) Speziale and Dyck
resolves10.1016/S1383-5718(01)00157-7
A comparison of intraperitoneal and oral gavage administration in comet assay in mouse eight organs
resolves10.1002/(SICI)1522-7278(199902)14:1<167::AID-TOX22>3.0.CO;2-O
Blooms of the cylindrospermopsin containing cyanobacterium,Aphanizomenon ovalisporum (Forti), in newly constructed lakes, Queensland, Australia
resolves10.1097/00007691-200002000-00019
Cylindrospermopsin, A Cyanobacterial Alkaloid: Evaluation of Its Toxicologic Activity
resolves10.1016/0165-1218(86)90032-7
A case for the continued use of the intraperitoneal route of exposure
resolves10.1016/S0041-0101(02)00151-4
Genotoxicity investigation of a cyanobacterial toxin, cylindrospermopsin
resolves10.1002/tox.20216
First observation of cylindrospermopsin in <i>Anabaena lapponica</i> isolated from the boreal environment (Finland)
resolves10.1016/S0009-2797(02)00038-8
DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique
resolves10.1016/0041-0101(94)90008-6
Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans
resolves10.1093/mutage/16.1.39
The in vivo gut micronucleus test detects clastogens and aneugens given by gavage
The 2 references without a DOI — listed, not checked
no DOI — not checkedStatistical Evaluation of Mutagenicity Test Data. UKEMS Sub‐Committee on Guidelines for Mutagenicity Testing, Report. Part III
no DOI — not checkedStandard Probability and Statistics Tables and Formulae
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