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Cannabinoids: Biosynthesis and Biotechnological Applications

https://doi.org/10.1007/978-3-319-54564-6_8
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The 93 checked references that resolve
resolves10.1021/ja053945v
Engineered Biosynthesis of Plant Polyketides:  Chain Length Control in an Octaketide-Producing Plant Type III Polyketide Synthase
resolves10.1039/b909988n
Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases
resolves10.3109/10242422.2016.1151006
Hydroxylation and glycosylation of Δ<sup>9</sup>-tetrahydrocannabinol by<i>Catharanthus roseus</i>cell suspension culture
resolves10.6026/97320630010033
Affinity comparison of different THCA synthase to CBGA using modeling computational approaches
resolves10.3389/fpls.2016.00019
Cannabis sativa: The Plant of the Thousand and One Molecules
resolves10.1021/np8002673
Antibacterial Cannabinoids from <i>Cannabis sativa</i>: A Structure−Activity Study
resolves10.1039/b100917f
The chalcone synthase superfamily of type III polyketide synthases
resolves10.1016/S1474-4422(03)00381-8
The therapeutic potential of cannabis
resolves10.1021/cr0406110
Biosynthetic and Biomimetic Electrocyclizations
resolves10.1111/pbi.12167
Targeted mutation of Δ12 and Δ15 desaturase genes in hemp produce major alterations in seed fatty acid composition including a high oleic hemp oil
resolves10.1007/s00299-011-1165-0
Exudation: an expanding technique for continuous production and release of secondary metabolites from plant cell suspension and hairy root cultures
resolves10.1111/j.1556-4029.2011.02021.x
Investigations into the Hypothesis of Transgenic Cannabis*
resolves10.1016/j.indcrop.2015.12.035
A rapid shoot regeneration protocol from the cotyledons of hemp (Cannabis sativa L.)
resolves10.1016/0031-9422(92)90016-J
Deguelin cyclase, a prenyl to chromen transforming enzyme from Tephrosia vogellii
resolves10.1021/cr00081a004
Biosynthesis and catabolism of monoterpenoids
resolves10.1074/jbc.M115.659631
Oxidation of Monolignols by Members of the Berberine Bridge Enzyme Family Suggests a Role in Plant Cell Wall Metabolism
resolves10.1093/genetics/163.1.335
The Inheritance of Chemical Phenotype in <i>Cannabis sativa</i> L.
resolves10.1126/science.1470919
Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor
resolves10.1126/science.175.4023.778
Cannabinoids with a Propyl Side Chain in Cannabis: Occurrence and Chromatographic Behavior
resolves10.1016/j.jbiotec.2014.11.016
Subcellular compartmentalization in protoplasts from Artemisia annua cell cultures: Engineering attempts using a modified SNARE protein
resolves10.1007/s00253-013-4925-7
Flavoprotein oxidases: classification and applications
resolves10.1073/pnas.88.22.9969
Molecular cloning, expression, and induction of berberine bridge enzyme, an enzyme essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack.
resolves10.1016/S1074-5521(98)90002-3
The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms
resolves10.1016/j.lfs.2005.09.011
Chemical constituents of marijuana: The complex mixture of natural cannabinoids
resolves10.4236/ajps.2015.611188
Cannabinoids Production by Hairy Root Cultures of &amp;lt;i&amp;gt;Cannabis sativa&amp;lt;/i&amp;gt; L.
resolves10.1079/IVP2003454
Tissue culture and Agrobacterium-mediated transformation of hemp (Cannabis sativa L.)
resolves10.1016/S0014-5793(98)00450-5
Prenylation of olivetolate by a hemp transferase yields cannabigerolic acid, the precursor of tetrahydrocannabinol
resolves10.1046/j.1432-1327.2001.02030.x
Biosynthesis of cannabinoids
resolves10.1007/s11101-008-9094-4
Secondary metabolism in cannabis
resolves10.1016/j.jbiotec.2009.05.006
Elicitation studies in cell suspension cultures of Cannabis sativa L.
resolves10.1073/pnas.1200330109
Identification of olivetolic acid cyclase from <i>Cannabis sativa</i> reveals a unique catalytic route to plant polyketides
resolves10.1126/science.aac9373
Complete biosynthesis of opioids in yeast
resolves10.3390/molecules191118781
Cannabinoids: New Promising Agents in the Treatment of Neurological Diseases
resolves10.1038/nrc1188
Cannabinoids: potential anticancer agents
resolves10.1073/pnas.0611629104
Omics-based identification of <i>Arabidopsis</i> Myb transcription factors regulating aliphatic glucosinolate biosynthesis
resolves10.1073/pnas.95.14.8268
Cannabidiol and (−)Δ <sup>9</sup> -tetrahydrocannabinol are neuroprotective antioxidants
resolves10.1016/0306-3623(81)90090-2
Cannabichromene and Δ9-tetrahydrocannabinol: Interactions relative to lethality, hypothermia and hexobarbital hypnosis
resolves10.1016/0031-9422(82)80016-2
The biogenesis of cannabinoids in Cannabis sativa
resolves10.2307/2446007
Immunochemical localization of Tetrahydrocannabinol (THC) in Cryofixed Glandular Trichomes of <i>Cannabis</i> (Cannabaceae)
resolves10.1007/BF02114192
Distribution of tetrahydrocannabinolic acid in fresh wild cannabis
resolves10.1248/cpb.28.594
Cannabis. XII. Variations of cannabinoid contents in several strains of Cannabis sativa L. with leaf-age, season and sex.
resolves10.1074/jbc.270.41.24475
Characterization and Mechanism of the Berberine Bridge Enzyme, a Covalently Flavinylated Oxidase of Benzophenanthridine Alkaloid Biosynthesis in Plants
resolves10.1016/j.jbiotec.2015.06.425
Δ9-Tetrahydrocannabinolic acid synthase production in Pichia pastoris enables chemical synthesis of cannabinoids
resolves10.1016/j.nbd.2004.11.009
Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: Relevance to Parkinson's disease
resolves10.1016/j.abb.2008.01.027
The growing VAO flavoprotein family
resolves10.1016/j.ymben.2009.10.001
Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism
resolves10.1016/j.molp.2015.03.012
MYB Transcription Factors as Regulators of Phenylpropanoid Metabolism in Plants
resolves10.1105/tpc.105.038018
The Structure of <i>Rauvolfia serpentina</i> Strictosidine Synthase Is a Novel Six-Bladed β-Propeller Fold in Plant Proteins
resolves10.1093/jxb/erp210
Identification of candidate genes affecting Δ9-tetrahydrocannabinol biosynthesis in Cannabis sativa
resolves10.1038/346561a0
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
resolves10.1126/science.168.3936.1159
Marihuana Chemistry
resolves10.1016/0006-2952(95)00109-D
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
resolves10.2174/1381612003399509
Looking Back at Cannabis Research
resolves10.1016/j.copbio.2013.09.009
Biochemical strategies for enhancing the in vivo production of natural products with pharmaceutical potential
resolves10.1021/np970210y
Enzymological Evidence for Cannabichromenic Acid Biosynthesis
resolves10.1016/S0031-9422(98)00278-7
Purification and characterization of cannabichromenic acid synthase from Cannabis sativa
resolves10.1074/jbc.M700133200
Identification and Characterization of Cannabinoids That Induce Cell Death through Mitochondrial Permeability Transition in Cannabis Leaf Cells
resolves10.1104/pp.114.246892
Molecular Cloning and Characterization of a Geranyl Diphosphate-Specific Aromatic Prenyltransferase from Lemon  
resolves10.1038/365061a0
Molecular characterization of a peripheral receptor for cannabinoids
resolves10.1038/nature12051
High-level semi-synthetic production of the potent antimalarial artemisinin
resolves10.1007/s10529-010-0225-9
Metabolic analysis of elicited cell suspension cultures of Cannabis sativa L. by 1H-NMR spectroscopy
resolves10.1021/np200500p
Bioactive Prenylogous Cannabinoid from Fiber Hemp (<i>Cannabis sativa</i>)
resolves10.1016/j.pbi.2015.04.001
Breaking new ground in the regulation of the early steps of plant isoprenoid biosynthesis
resolves10.1038/nchembio.141
Metabolic reprogramming of periwinkle plant culture
resolves10.1007/s002990100320
Feasible production of camptothecin by hairy root culture of Ophiorrhiza pumila
resolves10.1074/jbc.M403693200
The Gene Controlling Marijuana Psychoactivity
resolves10.1093/pcp/pci166
Tetrahydrocannabinolic Acid Synthase, the Enzyme Controlling Marijuana Psychoactivity, is Secreted into the Storage Cavity of the Glandular Trichomes
resolves10.1007/s11101-007-9080-2
Mechanisms of resistance to self-produced toxic secondary metabolites in plants
resolves10.1002/9781118794623.ch4
How Plants Avoid the Toxicity of Self‐Produced Defense Bioactive Compounds
resolves10.1016/S0031-9422(00)91096-3
Biosynthesis of cannabinoid acids
resolves10.1016/j.jmb.2012.06.030
Structure and Function of ∆1-Tetrahydrocannabinolic Acid (THCA) Synthase, the Enzyme Controlling the Psychoactivity of Cannabis sativa
resolves10.1111/j.1742-4658.2006.05588.x
A polyketide synthase of <i>Plumbago indica</i> that catalyzes the formation of hexaketide pyrones
resolves10.1111/j.1365-313X.2012.04949.x
The hexanoyl‐CoA precursor for cannabinoid biosynthesis is formed by an acyl‐activating enzyme in <i>Cannabis sativa</i> trichomes
resolves10.1006/bbrc.1995.2437
2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain
resolves10.1007/s40265-014-0197-5
Delta-9-Tetrahydrocannabinol/Cannabidiol (Sativex®): A Review of Its Use in Patients with Moderate to Severe Spasticity Due to Multiple Sclerosis
resolves10.1016/j.pep.2016.01.020
Potential of Synechocystis PCC 6803 as a novel cyanobacterial chassis for heterologous expression of enzymes in the trans-resveratrol biosynthetic pathway
resolves10.1021/ja00143a024
First direct evidence for the mechanism of .DELTA.1-tetrahydrocannabinolic acid biosynthesis
resolves10.1074/jbc.271.29.17411
Purification and Characterization of Cannabidiolic-acid Synthase from Cannabis sativa L.
resolves10.1016/j.bbrc.2007.07.079
Production of Δ1-tetrahydrocannabinolic acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris
resolves10.1016/j.febslet.2007.05.043
Cannabidiolic‐acid synthase, the chemotype‐determining enzyme in the fiber‐type <i>Cannabis sativa</i>
resolves10.1016/j.febslet.2009.05.024
Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway
resolves10.1038/sj.bjp.0706414
Evidence that the plant cannabinoid Δ<sup>9</sup>‐tetrahydrocannabivarin is a cannabinoid CB<sub>1</sub>and CB<sub>2</sub>receptor antagonist
resolves10.1002/j.1552-4604.1981.tb02606.x
Biological Activity of Cannabichromene, its Homologs and Isomers
resolves10.1186/gb-2011-12-10-r102
The draft genome and transcriptome of Cannabis sativa
resolves10.1080/17429145.2012.746399
<i>Agrobacterium</i>infection of hemp (<i>Cannabis sativa</i>L.): establishment of hairy root cultures
resolves10.1111/nph.13562
Gene duplication and divergence affecting drug content in <i>Cannabis sativa</i>
resolves10.1016/0003-9861(88)90627-3
Induction of phytoalexin synthesis in soybean: Enzymatic cyclization of prenylated pterocarpans to glyceollin isomers
resolves10.1038/nchembio.123
A concerted mechanism for berberine bridge enzyme
resolves10.1248/cpb.15.1075
Tetrahydrocannabinolic Acid, a Genuine Substance of Tetrahydrocannabinol
resolves10.1111/febs.13654
Structural basis for olivetolic acid formation by a polyketide cyclase from <i>Cannabis sativa</i>
resolves10.1016/j.phytochem.2009.08.023
Prenylation of aromatic compounds, a key diversification of plant secondary metabolites
resolves10.1248/yakushi1947.100.6_611
Plant Breeding of Cannabis. Determination of Cannabinoids by High-Pressure Liquid Chromatography
resolves10.1007/s10529-015-1853-x
Production of Δ9-tetrahydrocannabinolic acid from cannabigerolic acid by whole cells of Pichia (Komagataella) pastoris expressing Δ9-tetrahydrocannabinolic acid synthase from Cannabis sativa l.
The 6 references without a DOI — listed, not checked
no DOI — not checkedDewick PM (2002) Aromatic polyketides. In: Medicinal natural products. a biosynthetic approach, Ed2. Wiley, Sussex, UK, pp 60–92
no DOI — not checkedFairbairn JW (1972) The trichomes and glands of Cannabis sativa L. Bull Narc 23:29–33
no DOI — not checkedGaoni Y, Mechoulam R (1964) Isolation, structure, and partial synthesis of an active constituent of hashish. J Am Chem Soc 86:1946–1647
no DOI — not checkedPage JE, Boubakir Z (2011) Aromatic prenyltransferase from Cannabis. Patent WO 2011(017798):A1
no DOI — not checkedShoyama Y, Takeuchi A, Taura F, Tamada T, Adachi M, Kuroki R, Shoyama Y, Morimoto S (2005) Crystallization of ∆1-tetrahydrocannabinolic acid (THCA) synthase from Cannabis sativa. Acta Cryst F61:799–801
no DOI — not checkedTaura F, Sirikantaramas S, Shoyama Y, Shoyama Y, Morimoto S (2009a) Phytocannabinoids in Cannabis sativa: Recent studies on biosynthetic enzymes. In: Lambert DM (ed) Cannabinoids in nature and medicine. Wiley-VHCA AG, pp 51–65
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