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Resveratrol inhibits renal interstitial fibrosis in diabetic nephropathy by regulating AMPK/NOX4/ROS pathway
47/47 checkable references clean · checked 2026-07-22
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 47 checked references that resolve
resolves10.1038/nrneph.2009.74
Fibroblast activation and myofibroblast generation in obstructive nephropathy
resolves10.1172/JCI57301
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice
resolves10.1152/ajprenal.00546.2013
RhoA/Rho kinase mediates TGF-β<sub>1</sub>-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species
resolves10.1681/ASN.2009020146
NAD(P)H Oxidase Mediates TGF-β1–Induced Activation of Kidney Myofibroblasts
resolves10.1016/j.jacc.2003.06.010
Involvement of reactive oxygen species in angiotensin II-induced endothelin-1 gene expression in rat cardiac fibroblasts
resolves10.1016/j.mce.2014.12.010
Resveratrol prevents high glucose-induced epithelial–mesenchymal transition in renal tubular epithelial cells by inhibiting NADPH oxidase/ROS/ERK pathway
resolves10.1074/jbc.M502412200
Nox4 NAD(P)H Oxidase Mediates Hypertrophy and Fibronectin Expression in the Diabetic Kidney
resolves10.2337/db12-1504
Mammalian Target of Rapamycin Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury
resolves10.1016/j.cellsig.2006.10.004
AICAR potentiates ROS production induced by chronic high glucose: Roles of AMPK in pancreatic β-cell apoptosis
resolves10.2337/db06-0006
Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States
resolves10.1113/jphysiol.2006.108324
AMPK and cell proliferation – AMPK as a therapeutic target for atherosclerosis and cancer
resolves10.1038/nm788
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
resolves10.1074/jbc.M110.136796
AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes
resolves10.1152/ajprenal.00148.2012
AMP-activated protein kinase inhibits TGF-β-, angiotensin II-, aldosterone-, high glucose-, and albumin-induced epithelial-mesenchymal transition
resolves10.1159/000369687
AMP-Activated Protein Kinase Alleviates Extracellular Matrix Accumulation in High Glucose-Induced Renal Fibroblasts through mTOR Signaling Pathway
resolves10.1172/JCI66218
AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function
resolves10.1016/j.jnutbio.2014.03.010
Increase in AMPK brought about by cocoa is renoprotective in experimental diabetes mellitus by reducing NOX4/TGFβ-1 signaling
resolves10.1159/000089720
Resveratrol, a Polyphenolic Phytoalexin, Attenuates Diabetic Nephropathy in Rats
resolves10.1016/j.bbadis.2011.03.008
Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling
resolves10.1016/j.cmet.2010.04.001
Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
resolves10.1007/s00125-012-2747-2
Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice
resolves10.1002/path.4420
Klotho suppresses renal tubulo‐interstitial fibrosis by controlling basic fibroblast growth factor‐2 signalling
resolves10.1046/j.1523-1755.2000.00928.x
Role of glomerular ultrafiltration of growth factors in progressive interstitial fibrosis in diabetic nephropathy
resolves10.1007/s00418-008-0433-8
Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat
resolves10.1016/S0002-9440(10)61208-4
Origin of Interstitial Fibroblasts in an Accelerated Model of Angiotensin II-Induced Renal Fibrosis
resolves10.1016/j.cmet.2011.12.009
Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells
resolves10.1093/ndt/gfq749
Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide
resolves10.1152/ajprenal.00475.2009
Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3β, Snail1, and β-catenin in renal proximal tubule cells
resolves10.1111/j.1523-1755.2005.00494.x
Catalase deficiency renders remnant kidneys more susceptible to oxidant tissue injury and renal fibrosis in mice
resolves10.1038/nm.2005
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
resolves10.1111/j.1440-1797.2005.00448.x
Reactive oxygen species amplify glucose signalling in renal cells cultured under high glucose and in diabetic kidney
resolves10.2337/diabetes.55.01.06.db05-0894
Glucose-Induced Reactive Oxygen Species Cause Apoptosis of Podocytes and Podocyte Depletion at the Onset of Diabetic Nephropathy
resolves10.1152/ajprenal.00028.2010
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy
resolves10.1074/jbc.M406486200
Direct Interaction of the Novel Nox Proteins with p22phox Is Required for the Formation of a Functionally Active NADPH Oxidase
resolves10.3109/0886022X.2013.844644
Resveratrol as a therapeutic agent for renal fibrosis induced by unilateral ureteral obstruction
resolves10.2337/db10-0386
Resveratrol Improves Oxidative Stress and Protects Against Diabetic Nephropathy Through Normalization of Mn-SOD Dysfunction in AMPK/SIRT1-Independent Pathway
resolves10.1159/000300388
Resveratrol Attenuates Renal Hypertrophy in Early-Stage Diabetes by Activating AMPK
resolves10.1016/j.mehy.2008.12.024
AMP-activated kinase may suppress NADPH oxidase activation in vascular tissues
resolves10.1161/ATVBAHA.110.219543
α1AMP-Activated Protein Kinase Preserves Endothelial Function During Chronic Angiotensin II Treatment by Limiting Nox2 Upregulation
The 2 references without a DOI — listed, not checked
no DOI — not checkedLi JM, Shah AM (2003) ROS generation by nonphagocytic NADPH oxidase: potential relevance in diabetic nephropathy. J Am Soc Nephrol 14(8 Suppl 3):S221–S226
no DOI — not checkedSpanier G, Xu H, Xia N, Tobias S, Deng S, Wojnowski L, Forstermann U, Li H (2009) Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and NADPH oxidase subunit (Nox4). J Physiol Pharmacol 60(Suppl 4):111–116
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