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Cardiotoxicity of fluoropyrimidines in different schedules of administration: a prospective study
20/20 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
10 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 20 checked references that resolve
resolves10.1159/000227226
Symptomatic Cardiotoxicity with High-Dose 5-Fluorouracil Infusion: A Prospective Study
resolves10.1093/oxfordjournals.annonc.a010723
The influence of 5-fluorouracil and methotrexate on vascular endothelium. An experimental study using endothelial cells in the culture
resolves10.1200/JCO.1992.10.11.1795
Cardiotoxicity of high-dose continuous infusion fluorouracil: a prospective clinical study.
resolves10.1002/1097-0142(19880101)61:1<36::AID-CNCR2820610108>3.0.CO;2-6
5-Fluorouracil-associated cardiotoxicity
resolves10.1093/annonc/mdf035
Capecitabine can induce acute coronary syndrome similar to5-fluorouracil
resolves10.1023/A:1008263321681
Noninvasive evaluation of cardiotoxicity of 5-fluorouracil and low doses of folinic acid: A one-year follow-up study
resolves10.1007/s00280-005-0178-1
Risk factors and prevention of cardiotoxicity induced by 5-fluorouracil or capecitabine
resolves10.1016/0140-6736(91)91353-V
Fluoroacetaldehyde as cardiotoxic impurity in fluorouracil (Roche)
resolves10.1200/JCO.1989.7.4.509
Continuous ambulatory ECG monitoring during fluorouracil therapy: a prospective study.
resolves10.1002/1097-0142(19931001)72:7<2242::AID-CNCR2820720730>3.0.CO;2-E
Cardiotoxicity of 5-fluorouracil in combination with folinic acid in patients with gastrointestinal cancer
resolves10.1093/annonc/mdf108
Incidence of cardiotoxicity with the oral fluoropyrimidine capecitabine is typical of that reported with 5-fluorouracil
The 10 references without a DOI — listed, not checked
no DOI — not checkedCwikiel M, Zhang B, Eskilsson J, Wieslander JB, Albertsson M (1995) The influence of 5-fluorouracil on the endothelium in small arteries. An electron microscopic study in rabbits. Scanning Microsc 9:561–576
no DOI — not checkedCwikiel M, Eskilsson J, Wieslander JB, Stjernquist U, Albertsson M (1996b) The appearance of endothelium in small arteries after the treatment with 5-fluorouracil. An electron microscopic study of late effects in rabbits. Scan Micros 10:187–192
no DOI — not checkedGaveau T, Banzet P, Marneffe H, Viars P (1969) Traubles cardiovasculaires au cours d’infusions d’anti-mitociques a fortes doses: 30 observacions cliniques. Anaesth Analg (Paris) 26:311–327
no DOI — not checkedGrem JL (1996) 5-Fluoropyrimidines. In: Chabner BA, Longo DL (eds) Cancer chemotherapy and biotherapy: principles and practice, 2nd edn. Lippincott-Raven, Philadelphia, p 149
no DOI — not checkedLevillain R (1972) Experimental myocarditis; anatomical study of 210 rat hearts after ingestion of 5-fluorouracil. C R Seances Soc Biol Fil 166:340–342
no DOI — not checkedMoertel CG Reitermeier RJ (1962) Experience with 5-Fluoruracil in the palliative management of advanced carcinoma of the gastrointestinal track. Staff meeting of the Mayo Clinic. Mayo Clinic Proc 37:520–529
no DOI — not checkedMosseri M, Fingert HJ, Varticovski L, Chokshi S, Isner JM (1993) In vitro evidence that myocardial ischemia resulting from 5-fluorouracil chemotherapy is due to protein kinase C-mediated vasoconstriction of vascular smooth muscle. Cancer Res 53:3028–3033
no DOI — not checkedPorta C, Moroni M, Ferrari S, Nastasi G (1998) Endothelin-1 and 5-fluorouracil induced cardiotoxicity. Neoplasma 45:81–82
no DOI — not checkedRoth A, Kolaric K, Popovic S (1975) Cardiotoxicity of 5-fluorouracil (NSC 1993). Cancer Chemother Rep 59:1051–1052
no DOI — not checkedSasson Z, Morgan CD, Wang B, Thomas G, MacKenzie B, Platts ME (1994) 5-Fluorouracil related toxic myocarditis: case reports and pathological confirmation. Can J Carrdiol 10:861–864
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