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Dapagliflozin and Ticagrelor Have Additive Effects on the Attenuation of the Activation of the NLRP3 Inflammasome and the Progression of Diabetic Cardiomyopathy: an AMPK–mTOR Interplay
46/46 checkable references clean · checked 2026-08-10
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 46 checked references that resolve
resolves10.1093/eurheartj/ehz486
2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD
resolves10.1056/NEJMoa0904327
Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes
resolves10.1007/s10557-016-6701-2
Ticagrelor and Rosuvastatin Have Additive Cardioprotective Effects via Adenosine
resolves10.33594/000000189
Ticagrelor Improves Remodeling, Reduces Apoptosis, Inflammation and Fibrosis and Increases the Number of Progenitor Stem Cells After Myocardial Infarction in a Rat Model of Ischemia Reperfusion
resolves10.1161/ATVBAHA.115.305655
Ticagrelor Protects the Heart Against Reperfusion Injury and Improves Remodeling After Myocardial Infarction
resolves10.1007/s10557-017-6763-9
Unraveling the Interaction of Aspirin, Ticagrelor, and Rosuvastatin on the Progression of Atherosclerosis and Inflammation in Diabetic Mice
resolves10.1007/s00125-017-4390-4
Diabetic cardiomyopathy: a hyperglycaemia- and insulin-resistance-induced heart disease
resolves10.4239/wjd.v10.i10.490
Diabetic cardiomyopathy: Pathophysiology, theories and evidence to date
resolves10.1007/s10557-017-6725-2
SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation of the Effects with Saxagliptin, a DPP4 Inhibitor
resolves10.1161/CIRCHEARTFAILURE.119.006277
Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure
resolves10.1007/s10557-018-6837-3
Dapagliflozin Attenuates Na+/H+ Exchanger-1 in Cardiofibroblasts via AMPK Activation
resolves10.1016/j.pharep.2019.06.004
Effects of ticagrelor, empagliflozin and tamoxifen against experimentally-induced vascular reactivity defects in rats in vivo and in vitro
resolves10.1093/cvr/cvy201
P2Y12 antagonists and cardiac repair post-myocardial infarction: global and regional heart function analysis and molecular assessments in pigs
resolves10.1038/s41598-018-34492-7
Ageratina adenophora induces mice hepatotoxicity via ROS-NLRP3-mediated pyroptosis
resolves10.1152/ajpheart.00158.2018
Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury
resolves10.1161/CIRCULATIONAHA.119.039996
Dapagliflozin and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Previous Myocardial Infarction
resolves10.1016/S0140-6736(19)31887-2
Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo-controlled, randomised trial
resolves10.1681/ASN.2018080862
Erythrocyte Adenosine A2B Receptor-Mediated AMPK Activation: A Missing Component Counteracting CKD by Promoting Oxygen Delivery
resolves10.1016/j.cmet.2018.06.013
A2A Receptor Activation Attenuates Hypertensive Cardiac Remodeling via Promoting Brown Adipose Tissue-Derived FGF21
resolves10.1097/FJC.0b013e31819fd4e7
Metformin Prevents Myocardial Reperfusion Injury by Activating the Adenosine Receptor
resolves10.1007/s00018-016-2407-7
Targeting the energy guardian AMPK: another avenue for treating cardiomyopathy?
resolves10.18632/oncotarget.12119
β-Hydroxybutyrate suppresses inflammasome formation by ameliorating endoplasmic reticulum stress <i>via</i> AMPK activation
resolves10.1016/j.yjmcc.2008.12.023
Anti-hypertrophic effect of NHE-1 inhibition involves GSK-3β-dependent attenuation of mitochondrial dysfunction
resolves10.1152/ajpheart.00414.2014
The beneficial effects of AMP kinase activation against oxidative stress are associated with prevention of PPARα-cyclophilin D interaction in cardiomyocytes
resolves10.1161/CIRCRESAHA.114.302022
Mammalian Target of Rapamycin Signaling in Cardiac Physiology and Disease
resolves10.1007/s11892-017-0865-4
The mTOR Signaling Pathway in Myocardial Dysfunction in Type 2 Diabetes Mellitus
resolves10.1172/JCI43008
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice
resolves10.1152/ajpcell.00338.2010
mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy
resolves10.1096/fj.201901206R
Enhanced mTOR complex 1 signaling attenuates diabetic cardiac injury in OVE26 mice
resolves10.1038/nature06322
mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
resolves10.1152/ajpheart.00877.2012
Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α
resolves10.1161/CIRCRESAHA.117.311147
New Insights Into the Role of mTOR Signaling in the Cardiovascular System
resolves10.1016/j.cellsig.2018.08.009
FOXO3a-dependent up-regulation of Mxi1-0 promotes hypoxia-induced apoptosis in endothelial cells
resolves10.1080/15548627.2015.1051295
Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes
resolves10.1126/science.1215135
Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
resolves10.1007/s10557-014-6546-5
PTEN Upregulation May Explain the Development of Insulin Resistance and Type 2 Diabetes with High Dose Statins
The 2 references without a DOI — listed, not checked
no DOI — not checkedMcMurray JJV, Solomon SD, Inzucchi SE, Kober L, Kosiborod MN, Martinez FA, et al. Dapagliflozin in patients with heart failure and reduced ejection fraction. N Engl J Med. 2019.
no DOI — not checkedLiu MH, Li GH, Peng LJ, Qu SL, Zhang Y, Peng J, et al. PI3K/Akt/FoxO3a signaling mediates cardioprotection of FGF-2 against hydrogen peroxide-induced apoptosis in H9c2 cells. Mol Cell Biochem. 2016;414(1–2):57–66.
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