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In Vivo Tumor Growth Inhibition and Antiangiogenic Effect of Cyclic NGR Peptide-Daunorubicin Conjugates Developed for Targeted Drug Delivery
71/71 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
10 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 71 checked references that resolve
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Tumor Vasculature Targeting Through NGR Peptide-Based Drug Delivery Systems
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Synthesis and in vitro biochemical evaluation of oxime bond-linked daunorubicin–GnRH-III conjugates developed for targeted drug delivery
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Future of Monoclonal Antibodies in the Treatment of Hematologic Malignancies
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Small antibody mimetics comprising two complementarity-determining regions and a framework region for tumor targeting
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Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification
resolves10.1002/ijc.2910540122
Role of aminopeptidase N (CD13) in tumor‐cell invasion and extracellular matrix degradation
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Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model
resolves10.1016/S0092-8674(00)80108-7
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
resolves10.1038/s41388-018-0213-4
NGR (Asn-Gly-Arg)-targeted delivery of coagulase to tumor vasculature arrests cancer cell growth
resolves10.1016/0268-960X(92)90020-Q
The significance of aminopeptidases and haematopoietic cell differentiation
resolves10.1136/jcp.47.1.43
Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin.
resolves10.1182/blood.V97.3.652
CD13/APN is activated by angiogenic signals and is essential for capillary tube formation
resolves10.1016/j.canlet.2005.11.051
Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis
resolves10.1053/gast.2002.31095
Aminopeptidase N is involved in cell motility and angiogenesis: Its clinical significance in human colon cancer
resolves10.1002/cncr.21149
Addition of an aminopeptidase N‐binding sequence to human endostatin improves inhibition of ovarian carcinoma growth
resolves10.1161/01.ATV.0000245807.65714.0b
cNGR: A Novel Homing Sequence for CD13/APN Targeted Molecular Imaging of Murine Cardiac Angiogenesis In Vivo
resolves10.1089/104303404322959524
Inhibition of Tumor Growth by Intramuscular Injection of cDNA Encoding Tumor Necrosis Factor
<i>α</i>
Coupled to NGR and RGD Tumor-Homing Peptides
resolves10.1182/blood-2008-04-150318
Infarction of tumor vessels by NGR-peptide–directed targeting of tissue factor: experimental results and first-in-man experience
resolves10.1158/0008-5472.CAN-08-0689
Quantitative Molecular Magnetic Resonance Imaging of Tumor Angiogenesis Using cNGR-Labeled Paramagnetic Quantum Dots
resolves10.1038/81183
Enhancement of tumor necrosis factor α antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
resolves10.1158/0008-5472.CAN-06-2117
Targeting Liposomal Chemotherapy via Both Tumor Cell–Specific and Tumor Vasculature–Specific Ligands Potentiates Therapeutic Efficacy
resolves10.1021/bc070031k
Conjugated Platinum(IV)−Peptide Complexes for Targeting Angiogenic Tumor Vasculature
resolves10.1039/b417734g
Synthesis and photochemical properties of photoactivated antitumor prodrugs releasing 5-fluorouracil
resolves10.3390/ijms18020429
Succinimide Formation from an NGR-Containing Cyclic Peptide: Computational Evidence for Catalytic Roles of Phosphate Buffer and the Arginine Side Chain
resolves10.1016/S0021-9258(19)75855-4
Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.
resolves10.1016/j.jconrel.2009.12.031
Synthesis and in vitro evaluation of cyclic NGR peptide targeted thermally sensitive liposome
resolves10.1021/jm501630j
Development of Cyclic NGR Peptides with Thioether Linkage: Structure and Dynamics Determining Deamidation and Bioactivity
resolves10.1074/jbc.M109.044297
Critical Role of Flanking Residues in NGR-to-isoDGR Transition and CD13/Integrin Receptor Switching
resolves10.1074/jbc.M710273200
Structural Basis for the Interaction of isoDGR with the RGD-binding Site of αvβ3 Integrin
resolves10.1002/anie.201004363
Conformational Control of Integrin‐Subtype Selectivity in <i>iso</i>DGR Peptide Motifs: A Biological Switch
resolves10.3762/bjoc.14.78
Development of novel cyclic NGR peptide–daunomycin conjugates with dual targeting property
resolves10.1242/bio.2012364
Matched rabbit monoclonal antibodies against αv-series integrins reveal a novel αvβ3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors
resolves10.1111/j.1365-2133.2000.03709.x
Phenotypic characteristics of Kaposi's sarcoma tumour cells derived from patch-, plaque- and nodular-stage lesions: analysis of cell cultures isolated from AIDS and non-AIDS patients and review of the literature
resolves10.1016/j.tcb.2013.04.001
Cellular origin of Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus-induced cell reprogramming
resolves10.1097/00002030-199706000-00003
The β-core fragment of human chorionic gonadotrophin inhibits growth of Kaposiʼs sarcoma-derived cells and a new immortalized Kaposiʼs sarcoma cell line
resolves10.1007/BF01756387
Expression and role of integrins in adhesion of human colonic carcinoma cells to extracellular matrix components
resolves10.1128/JVI.01673-07
Integrin α
<sub>V</sub>
β
<sub>3</sub>
Binds to the RGD Motif of Glycoprotein B of Kaposi's Sarcoma-Associated Herpesvirus and Functions as an RGD-Dependent Entry Receptor
resolves10.1016/S1359-6101(97)00037-3
Kaposi's sarcoma: a result of the interplay among inflammatory cytokines, angiogenic factors and viral agents
resolves10.1128/JVI.01334-09
Early Events in Kaposi's Sarcoma-Associated Herpesvirus Infection of Target Cells
resolves10.1182/blood.V84.8.2711.2711
Identification and culture of Kaposi's sarcoma-like spindle cells from the peripheral blood of human immunodeficiency virus-1-infected individuals and normal controls [see comments]
resolves10.1002/anie.201007091
Use of Metadynamics in the Design of isoDGR‐Based αvβ3 Antagonists To Fine‐Tune the Conformational Ensemble
resolves10.1007/s00726-010-0766-1
In vitro degradation and antitumor activity of oxime bond-linked daunorubicin–GnRH-III bioconjugates and DNA-binding properties of daunorubicin–amino acid metabolites
resolves10.1002/(SICI)1097-4652(200003)182:3<311::AID-JCP1>3.0.CO;2-9
The Ki-67 protein: From the known and the unknown
resolves10.3748/wjg.v21.i41.11854
Animal models of human colorectal cancer: Current status, uses and limitations
resolves10.1007/s10637-016-0354-7
Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice
resolves10.1016/j.ejmech.2019.05.016
Sequence modification of heptapeptide selected by phage display as homing device for HT-29 colon cancer cells to improve the anti-tumour activity of drug delivery systems
resolves10.3390/ijms20194763
Improved In Vivo Anti-Tumor and Anti-Metastatic Effect of GnRH-III-Daunorubicin Analogs on Colorectal and Breast Carcinoma Bearing Mice
resolves10.1016/S0753-3322(05)80082-4
Natural killer cells in breast cancer cell growth and metastasis in SCID mice
The 10 references without a DOI — listed, not checked
no DOI — not checkedWang RE, Niu Y, Wu H, Amin MN, Cai J (2011) Development of NGR peptide-based agents for tumor imaging. Am J Nucl Med Mol Imaging 1(1):36–46
no DOI — not checkedMenrad A, Speicher D, Wacker J, Herlyn M (1993) Biochemical and functional characterization of aminopeptidase N expressed by human melanoma cells. Cancer Res 53(6):1450–1455
no DOI — not checkedChen H, Kinzer CA, Paul WE (1996) p161, a murine membrane protein expressed on mast cells and some macrophages, is mouse CD13/aminopeptidase N. J Immunol Baltim Md 157(6):2593–2600
no DOI — not checkedDrexler HG (1987) Classification of acute myeloid leukemias--a comparison of FAB and immunophenotyping. Leukemia 1(10):697–705
no DOI — not checkedMáté G, Kertész I, Enyedi KN et al (2015) In vivo imaging of aminopeptidase N (CD13) receptors in experimental renal tumors using the novel radiotracer (68)Ga-NOTA-c(NGR). Eur J Pharm Sci Off J Eur Fed Pharm Sci 69:61–71
no DOI — not checkedCorti A (2004) Strategies for improving the anti-neoplastic activity of TNF by tumor targeting. Methods Mol Med 98:247–264
no DOI — not checkedCorti A, Curnis F, Rossoni G, Marcucci F, Gregorc V (2013) Peptide-mediated targeting of cytokines to tumor vasculature: the NGR-hTNF example. BioDrugs Clin Immunother Biopharm Gene Ther 27(6):591–603
no DOI — not checkedMingozzi M, Dal Corso A, Marchini M et al (2013) Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands. Chem Weinh Bergstr Ger 19(11):3563–3567
no DOI — not checkedKuntzman R, Mark LC, Brand LC et al (1966) Metabolism of drugs and carcinogens by human liver enzymes. J Pharmacol Exp Ther 152(1):151–156
no DOI — not checkedHirst DG, Denekamp J (1979) Tumour cell proliferation in relation to the vasculature. Cell Tissue Kinet 12(1):31–42
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