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Bee venom for the treatment of Parkinson’s disease: How far is it possible?
80/80 checkable references clean · checked 2026-07-25
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
8 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 80 checked references that resolve
resolves10.1146/annurev.neuro.26.043002.094919
E<scp>PIDEMIOLOGY OF</scp>N<scp>EURODEGENERATION</scp>
resolves10.1016/S1474-4422(06)70373-8
Non-motor symptoms of Parkinson's disease: diagnosis and management
resolves10.1016/j.cnr.2006.09.006
Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease
resolves10.3390/toxins7083179
Pharmacological Alternatives for the Treatment of Neurodegenerative Disorders: Wasp and Bee Venoms and Their Components as New Neuroactive Tools
resolves10.1007/s00702-016-1603-9
Therapies for Parkinson’s diseases: alternatives to current pharmacological interventions
resolves10.1007/s00726-001-0119-1
Recognition and treatment of response fluctuations in Parkinson's disease: Review article
resolves10.1056/NEJM200005183422004
A Five-Year Study of the Incidence of Dyskinesia in Patients with Early Parkinson's Disease Who Were Treated with Ropinirole or Levodopa
resolves10.1016/j.biopha.2015.01.029
Neurobiology of l-DOPA induced dyskinesia and the novel therapeutic strategies
resolves10.1016/j.ejphar.2015.01.030
Management of Parkinson׳s disease: Current and future pharmacotherapy
resolves10.1016/j.pharmthera.2007.04.004
Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds
resolves10.3390/toxins7072413
Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases
resolves10.1089/acm.2014.0220
Long-Term Effectiveness of Bee Venom Acupuncture and Physiotherapy in the Treatment of Adhesive Capsulitis: A One-Year Follow-Up Analysis of a Previous Randomized Controlled Trial
resolves10.1248/bpb.b14-00797
Nicotinic Acetylcholine Receptors Mediate the Suppressive Effect of an Injection of Diluted Bee Venom into the GV3 Acupoint on Oxaliplatin-Induced Neuropathic Cold Allodynia in Rats
resolves10.1177/1091581809335051
Radioprotective Effects of Honeybee Venom (
<i>Apis mellifera</i>
) Against 915-MHz Microwave Radiation–Induced DNA Damage in Wistar Rat Lymphocytes: In Vitro Study
resolves10.1016/j.canlet.2009.11.013
Bee venom inhibits tumor angiogenesis and metastasis by inhibiting tyrosine phosphorylation of VEGFR-2 in LLC-tumor-bearing mice
resolves10.1211/jpp.58.1.0010
Effect of polypeptides in bee venom on growth inhibition and apoptosis induction of the human hepatoma cell line SMMC-7721 in-vitro and Balb/c nude mice in-vivo
resolves10.1016/j.cyto.2012.10.005
Bee venom ameliorates ovalbumin induced allergic asthma via modulating CD4+CD25+ regulatory T cells in mice
resolves10.1016/0160-9327(88)90082-8
Honeybee venom: A rich source of pharmacologically active peptides
resolves10.4142/jvs.2004.5.4.309
General pharmacological profiles of bee venom and its water soluble fractions in rodent models
resolves10.3390/toxins7041126
Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan
resolves10.1517/14728222.2013.823161
The therapeutic potential of small-conductance KCa2 channels in neurodegenerative and psychiatric diseases
resolves10.1523/JNEUROSCI.22-23-10163.2002
Small Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup>Channels Modulate Synaptic Plasticity and Memory Encoding
resolves10.1186/1742-2094-7-69
Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models
resolves10.3390/toxins7030846
The Effects of Bee Venom Acupuncture on the Central Nervous System and Muscle in an Animal hSOD1G93A Mutant
resolves10.1186/s12974-016-0476-z
Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer’s disease
resolves10.1016/S0969-9961(02)00017-7
Up-regulation of inducible nitric oxide synthase in the substantia nigra by lipopolysaccharide causes microglial activation and neurodegeneration
resolves10.1096/fj.03-0109fje
Critical role of microglial NADPH oxidase‐derived free radicals in the in vitro MPTP model of Parkinson's disease
resolves10.1073/pnas.0937239100
NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
resolves10.1002/ana.20338
Microglial activation and dopamine terminal loss in early Parkinson's disease
resolves10.1016/j.intimp.2007.04.005
Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia
resolves10.1016/j.jep.2005.02.026
Effects of bee venom on the pro-inflammatory responses in RAW264.7 macrophage cell line
resolves10.1016/j.bbi.2012.08.013
Neuro-protective effects of bee venom by suppression of neuroinflammatory responses in a mouse model of Parkinson’s disease: Role of regulatory T cells
resolves10.1002/ana.410360305
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
resolves10.1016/j.neuropharm.2009.11.017
The effect of antiparkinsonian drugs on oxidative stress induced pathological [3H]dopamine efflux after in vitro rotenone exposure in rat striatal slices
resolves10.1159/000323265
Serological Profiles of Urate, Paraoxonase-1, Ferritin and Lipid in Parkinson’s Disease: Changes Linked to Disease Progression
resolves10.1016/j.neuint.2014.11.008
Neuroprotective effects of bee venom acupuncture therapy against rotenone-induced oxidative stress and apoptosis
resolves10.1006/bbrc.1997.7295
Melittin Binds to Secretory Phospholipase A2and Inhibits Its Enzymatic Activity
resolves10.1016/S1388-1981(99)00157-2
Structure-based design of a new class of anti-inflammatory drugs: secretory phospholipase A2 inhibitors, SPI
resolves10.1016/S0301-0082(01)00003-X
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease
resolves10.1073/pnas.232473399
Caspase activation and neuroprotection in caspase-3- deficient mice after
<i>in vivo</i>
cerebral ischemia and
<i>in vitro</i>
oxygen glucose deprivation
resolves10.1016/j.brainres.2011.10.003
Bee venom protects SH-SY5Y human neuroblastoma cells from 1-methyl-4-phenylpyridinium-induced apoptotic cell death
resolves10.1016/S0006-8993(02)03216-X
Methylpyridinium (MPP+)- and nerve growth factor-induced changes in pro- and anti-apoptotic signaling pathways in SH-SY5Y neuroblastoma cells
resolves10.1179/016164109X12537002794282
Neuroprotective effects of bee venom pharmaceutical acupuncture in acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease
resolves10.1002/jnr.10426
Protective effect of dopamine D2 agonists in cortical neurons via the phosphatidylinositol 3 kinase cascade
resolves10.1016/S0006-8993(03)03454-1
Agmatine induces glutamate release and cell death in cultured rat cerebellar granule neurons
resolves10.1074/jbc.272.30.18518
Activation and Involvement of p38 Mitogen-activated Protein Kinase in Glutamate-induced Apoptosis in Rat Cerebellar Granule Cells
resolves10.1016/j.jneuroim.2005.04.025
Proinflammatory cytokines and apoptosis following glutamate-induced excitotoxicity mediated by p38 MAPK in the hippocampus of neonatal rats
resolves10.1002/mds.20503
Evaluation of acupuncture in the treatment of Parkinson's disease: A double‐blind pilot study
resolves10.1037/0735-7044.111.3.579
Disruption of the dopamine Β-hydroxylase gene in mice suggests roles for norepinephrine in motor function, learning, and memory.
resolves10.1371/journal.pone.0061700
Bee Venom and Its Component Apamin as Neuroprotective Agents in a Parkinson Disease Mouse Model
resolves10.1371/journal.pone.0142838
Bee Venom Alleviates Motor Deficits and Modulates the Transfer of Cortical Information through the Basal Ganglia in Rat Models of Parkinson’s Disease
resolves10.1523/JNEUROSCI.5668-03.2004
Rescue of Mesencephalic Dopaminergic Neurons in Culture by Low-Level Stimulation of Voltage-Gated Sodium Channels
resolves10.3109/00207454.2010.548613
Bee Venom Reduces Neuroinflammation in the MPTP-Induced Model of Parkinson's Disease
resolves10.1016/j.parkreldis.2012.04.030
Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson's disease
resolves10.1089/acm.2015.0078
A Prospective Open-Label Study of Combined Treatment for Idiopathic Parkinson's Disease Using Acupuncture and Bee Venom Acupuncture as an Adjunctive Treatment
resolves10.1371/journal.pone.0158235
Bee Venom for the Treatment of Parkinson Disease – A Randomized Controlled Clinical Trial
resolves10.1016/j.biopha.2016.11.074
Neuroprotective mechanisms of plant extracts against MPTP induced neurotoxicity: Future applications in Parkinson’s disease
The 8 references without a DOI — listed, not checked
no DOI — not checkedLevodopa phobia: a new iatrogenic cause of disability in Parkinson disease
no DOI — not checkedInhibitory effect of whole bee venom in adjuvant-induced arthritis
no DOI — not checkedStudies on bee venom and its medical uses
no DOI — not checkedThe effect of mellitin-the major constituent of the bee venom-on the central nervous system
no DOI — not checkedTowards therapeutic applications of arthropod venom K
no DOI — not checkedEffect of honey bee venom on lewis rats with experimental allergic encephalomyelitis, a model for multiple sclerosis
no DOI — not checkedThe role of microglia and astrocytes in CNS immune surveillance and immunopathology
no DOI — not checkedEffects of bee venom on glutamate-induced toxicity in neuronal and glial cells
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