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Neuroprotective effect of early and short-time applying sophoridine in pMCAO rat brain: Down-regulated TRAF6 and up-regulated p-ERK1/2 expression, ameliorated brain infaction and edema

https://doi.org/10.1016/j.brainresbull.2012.04.003
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36/36 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 36 checked references that resolve
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Stroke treatment with alteplase given 3·0–4·5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial
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Tumor necrosis factor receptor-associated factors (TRAFs)
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Glutaredoxin-1 regulates TRAF6 activation and the IL-1 receptor/TLR4 signalling
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Increased Expression of TNF Receptor-Associated Factor 6 After Rat Traumatic Brain Injury
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Neuroprotection and underlying mechanisms of oxymatrine in cerebral ischemia of rats
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ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice
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Prereperfusion Saline Infusion Into Ischemic Territory Reduces Inflammatory Injury After Transient Middle Cerebral Artery Occlusion in Rats
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Inflammation and Infection in Clinical Stroke
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Inflammation in stroke and focal cerebral ischemia
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Inhibition of sonic hedgehog signaling aggravates brain damage associated with the down-regulation of Gli1, Ptch1 and SOD1 expression in acute ischemic stroke
resolves10.1084/jem.187.2.237
Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6) Stimulates Extracellular Signal–regulated Kinase (ERK) Activity in CD40 Signaling Along a Ras-independent Pathway
resolves10.1161/STROKEAHA.109.552547
Efficacy and Safety of Tissue Plasminogen Activator 3 to 4.5 Hours After Acute Ischemic Stroke
resolves10.1248/bpb.32.1521
Antiarrhythmic Properties of Long-Term Treatment with Matrine in Arrhythmic Rat Induced by Coronary Ligation
resolves10.1248/bpb.34.595
The Neuroprotection of Oxymatrine in Cerebral Ischemia/Reperfusion Is Related to Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2)-Mediated Antioxidant Response: Role of Nrf2 and Hemeoxygenase-1 Expression
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Tumor necrosis factor-alpha expression in ischemic neurons.
resolves10.1016/j.brainres.2009.02.069
Oxymatrine protects rat brains against permanent focal ischemia and downregulates NF-κB expression
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The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat
resolves10.1016/j.cardiores.2004.06.014
Inflammatory signaling pathway containing TRAF6 contributes to neointimal formation via diverse mechanisms
resolves10.4049/jimmunol.174.2.1081
TNF Receptor-Associated Factor 6 Is an Essential Mediator of CD40-Activated Proinflammatory Pathways in Monocytes and Macrophages
resolves10.1002/ana.20741
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resolves10.1161/01.STR.29.4.850
A Novel Endothelin Antagonist, A-127722, Attenuates Ischemic Lesion Size in Rats With Temporary Middle Cerebral Artery Occlusion
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Lovastatin protects mesenchymal stem cells against hypoxia‐ and serum deprivation‐induced apoptosis by activation of PI3K/Akt and ERK1/2
resolves10.1016/j.brainres.2009.05.009
Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia
resolves10.1016/j.lfs.2005.09.034
Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in rats
resolves10.1016/j.ejphar.2009.02.013
Comparative effects of sophocarpine and sophoridine on hERG K+ channel
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Effect of matrine on Kupffer cell activation in cold ischemia reperfusion injury of rat liver
resolves10.1074/jbc.M110.187591
Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Associates with Huntingtin Protein and Promotes Its Atypical Ubiquitination to Enhance Aggregate Formation
The 3 references without a DOI — listed, not checked
no DOI — not checkedEffects of matrine on inflammatory cytokines for rats with cerebral ischemia reperfusion injury
no DOI — not checkedTumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia–reperfusion injury in the pig retina
no DOI — not checkedAdvance in the pharmacological research on matrine
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