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Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells

https://doi.org/10.1016/j.ccell.2018.03.027
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39/39 checkable references clean · checked 2026-07-22

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

The 39 checked references that resolve
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cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
resolves10.1016/j.coi.2014.10.009
Self-DNA, STING-dependent signaling and the origins of autoinflammatory disease
resolves10.1073/pnas.1215006109
STING manifests self DNA-dependent inflammatory disease
resolves10.4049/jimmunol.1401337
Intrinsic Self-DNA Triggers Inflammatory Disease Dependent on STING
resolves10.1038/ncomms6166
Inflammation-driven carcinogenesis is mediated through STING
resolves10.1016/j.it.2013.10.010
STING-dependent cytosolic DNA sensing pathways
resolves10.1038/nri3921
STING: infection, inflammation and cancer
resolves10.4049/jimmunol.172.4.1996
Cutting Edge: Conventional CD8α+ Dendritic Cells Are Generally Involved in Priming CTL Immunity to Viruses
resolves10.1016/j.celrep.2015.04.031
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
resolves10.1016/j.immuni.2014.10.019
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
resolves10.1084/jem.20101158
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
resolves10.1038/nature24050
Cytoplasmic chromatin triggers inflammation in senescence and cancer
resolves10.1084/jem.20101159
Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells
resolves10.1038/ni.2703
Innate and adaptive immune cells in the tumor microenvironment
resolves10.1016/j.ccell.2015.10.012
Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents
resolves10.1073/pnas.1516465112
Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
resolves10.1038/nature23470
Mitotic progression following DNA damage enables pattern recognition within micronuclei
resolves10.1128/JVI.05408-11
Vesicular Stomatitis Virus Expressing Tumor Suppressor p53 Is a Highly Attenuated, Potent Oncolytic Agent
resolves10.1038/nature07317
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
resolves10.1038/nature08476
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
resolves10.1126/science.292.5521.1546
Requirement of DNase II for Definitive Erythropoiesis in the Mouse Fetal Liver
resolves10.1038/nri2215
How dying cells alert the immune system to danger
resolves10.1056/NEJMoa1312625
Activated STING in a Vascular and Pulmonary Syndrome
resolves10.1016/j.immuni.2013.03.003
Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells
resolves10.1038/nature23449
cGAS surveillance of micronuclei links genome instability to innate immunity
resolves10.1038/nm.2403
DNA released from dying host cells mediates aluminum adjuvant activity
resolves10.1101/gad.14.5.549
An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes
resolves10.1038/sj.cdd.4401161
Degradation of chromosomal DNA during apoptosis
resolves10.1038/nri.2016.153
Programmed cell death and the immune system
resolves10.1016/j.immuni.2015.11.024
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
resolves10.1016/j.ejca.2016.12.028
Rationale for stimulator of interferon genes–targeted cancer immunotherapy
resolves10.1084/jem.20161596
Type I interferon–mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overview
resolves10.1016/j.ymthe.2017.03.026
Oncolytic Virotherapy: A Contest between Apples and Oranges
resolves10.4049/jimmunol.170.9.4437
Cutting Edge: Conventional CD8α+ Dendritic Cells Are Preferentially Involved in CTL Priming After Footpad Infection with Herpes Simplex Virus-1
resolves10.1016/j.immuni.2014.10.017
STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
resolves10.1016/j.celrep.2015.12.029
Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
resolves10.1158/0008-5472.CAN-16-1404
Recurrent Loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis
resolves10.1038/nri.2017.9
Dying cells actively regulate adaptive immune responses
resolves10.1038/nri3845
Type I interferons in anticancer immunity
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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