Every reference with a DOI in the deposited reference list resolved to a known
work in Crossref or DataCite at the dated check, and none carried a retraction,
withdrawal, or removal notice.
The 53 checked references that resolve
resolves10.1038/nrd2590The exploration of macrocycles for drug discovery — an underexploited structural class
resolves10.1021/jm1012374Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery
resolves10.4155/fmc.14.133Macrocycles as Potential Therapeutic Agents in Neglected Diseases
resolves10.7164/antibiotics.28.727Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization.
resolves10.1021/ja00250a050Structure of FK506, a novel immunosuppressant isolated from Streptomyces
resolves10.1038/341758a0A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase
resolves10.1038/341755a0A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin
resolves10.1002/anie.201905578Discovery of a Potent GLUT Inhibitor from a Library of Rapafucins by Using 3D Microarrays
resolves10.1002/anie.201506846Olefin Metathesis at the Dawn of Implementation in Pharmaceutical and Specialty‐Chemicals Manufacturing
resolves10.1021/jo0158480Formation of Macrocycles <i>via</i> Ring-Closing Olefin Metathesis
resolves10.1021/acs.oprd.8b00093Ring-Closing Metathesis in Pharmaceutical Development: Fundamentals, Applications, and Future Directions
resolves10.1002/anie.200600641Macrocyclization by Ring‐Closing Metathesis in the Total Synthesis of Natural Products: Reaction Conditions and Limitations
resolves10.1039/C4CS00246FPeptide stapling techniques based on different macrocyclisation chemistries
resolves10.1039/C9OB02765CMacrocyclization
<i>via</i>
C–H functionalization: a new paradigm in macrocycle synthesis
resolves10.1039/c2cc36962aPeptidic macrocyclization via palladium-catalyzed chemoselective indole C-2 arylation
resolves10.1038/ncomms8160New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine residues
resolves10.1021/acs.orglett.9b02945Macrocyclization of Biaryl-Bridged Peptides through Late-Stage Palladium-Catalyzed C(sp<sup>2</sup>)–H Arylation
resolves10.1038/s41557-018-0006-yA general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp3 C−H arylation
resolves10.1021/jacs.9b04221Construction of Natural-Product-Like Cyclophane-Braced Peptide Macrocycles via sp
<sup>3</sup>
C–H Arylation
resolves10.1021/acs.orglett.0c02342Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular C(sp<sup>3</sup>)–H Arylation of <i>N</i>-Methyl Alanine at C-Termini
resolves10.1021/acs.orglett.0c02422Construction of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Picolinamide-Directed Intramolecular C(sp<sup>2</sup>)–H Arylation
resolves10.1002/anie.201611118Manganese‐Catalyzed C−H Alkynylation: Expedient Peptide Synthesis and Modification
resolves10.1126/sciadv.abe6202Late-stage stitching enabled by manganese-catalyzed C─H activation: Peptide ligation and access to cyclopeptides
resolves10.1021/acs.jcim.0c00898Substitution Effect of the Trifluoromethyl Group on the Bioactivity in Medicinal Chemistry: Statistical Analysis and Energy Calculations
resolves10.1021/jm0511334Incorporation of the Unusual C<sup>α</sup>-Fluoroalkylamino Acids into Cyclopeptides: Synthesis of Arginine−Glycine−Aspartate (RGD) Analogues and Study of Their Conformational and Biological Behavior
resolves10.1002/anie.201807953Backbone‐Enabled Directional Peptide Macrocyclization through Late‐Stage Palladium‐Catalyzed δ‐C(sp<sup>2</sup>)−H Olefination
resolves10.1038/s41467-018-05440-wPeptide-guided functionalization and macrocyclization of bioactive peptidosulfonamides by Pd(II)-catalyzed late-stage C–H activation
resolves10.1002/anie.202007226Late‐Stage Peptide Macrocyclization by Palladium‐Catalyzed Site‐Selective C−H Olefination of Tryptophan
resolves10.1021/acs.orglett.1c00580Late-Stage Macrocyclization of Bioactive Peptides with Internal Oxazole Motifs via Palladium-Catalyzed C–H Olefination
resolves10.1038/s41467-020-16084-0A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation
resolves10.1021/jacs.0c00078Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Macrocyclic P-glycoprotein Inhibitors
resolves10.1038/s41467-021-21484-xMarine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp3)-H olefination mediated by donor/donor carbenes
resolves10.1021/jacs.9b07185A Domino 10-Step Total Synthesis of FR252921 and Its Analogues, Complex Macrocyclic Immunosuppressants
resolves10.7164/antibiotics.56.55Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities of FR252921, FR252922 and FR256523.
resolves10.1111/imr.12853Adipose tissue macrophages: Unique polarization and bioenergetics in obesity
resolves10.1136/ard.2010.140145Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
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