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Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX
38/38 checkable references clean · checked 2026-07-25
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
The 38 checked references that resolve
resolves10.1038/cddis.2012.120
AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation
resolves10.1016/j.bmcl.2012.07.042
Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway
resolves10.1074/jbc.M611605200
Ataxia Telangiectasia Mutated (ATM) Is Essential for DNA-PKcs Phosphorylations at the Thr-2609 Cluster upon DNA Double Strand Break
resolves10.1126/science.1175371
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
resolves10.1038/nature07849
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
resolves10.1182/blood-2004-07-2888
Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway
resolves10.1016/j.str.2008.03.013
Ab Initio Folding of Proteins with All-Atom Discrete Molecular Dynamics
resolves10.1016/S1359-0278(98)00072-8
Discrete molecular dynamics studies of the folding of a protein-like model
resolves10.1074/mcp.M500327-MCP200
The Dynamic Alterations of H2AX Complex during DNA Repair Detected by a Proteomic Approach Reveal the Critical Roles of Ca2+/Calmodulin in the Ionizing Radiation-induced Cell Cycle Arrest
resolves10.1084/jem.20112343
Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response
resolves10.1016/j.cell.2012.02.013
Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
resolves10.1038/nature12147
The bromodomain protein Brd4 insulates chromatin from DNA damage signalling
resolves10.1016/j.cub.2010.11.058
Influence of Combinatorial Histone Modifications on Antibody and Effector Protein Recognition
resolves10.1128/MCB.22.24.8552-8561.2002
An ATR- and Chk1-Dependent S Checkpoint Inhibits Replicon Initiation following UVC-Induced DNA Damage
resolves10.1016/j.molcel.2008.02.029
FACT-Mediated Exchange of Histone Variant H2AX Regulated by Phosphorylation of H2AX and ADP-Ribosylation of Spt16
resolves10.1128/MCB.00579-07
DNA Damage-Dependent Acetylation and Ubiquitination of H2AX Enhances Chromatin Dynamics
resolves10.1126/science.1103455
Acetylation by Tip60 Is Required for Selective Histone Variant Exchange at DNA Lesions
resolves10.1038/cddis.2012.76
BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair
resolves10.1126/science.7855602
Absence of p350 Subunit of DNA-Activated Protein Kinase from a Radiosensitive Human Cell Line
resolves10.1038/nrc2248
The impact of a negligent G2/M checkpoint on genomic instability and cancer induction
resolves10.1093/emboj/19.22.6141
The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p
resolves10.1093/nar/gkg921
DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner
resolves10.1074/jbc.M110.101808
Transcription-dependent Activation of Ataxia Telangiectasia Mutated Prevents DNA-dependent Protein Kinase-mediated Cell Death in Response to Topoisomerase I Poison
resolves10.1038/nature08648
Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats
resolves10.1016/j.cell.2012.11.054
An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression
resolves10.1128/MCB.01382-07
DNA Damage-Induced Acetylation of Lysine 3016 of ATM Activates ATM Kinase Activity
resolves10.1016/j.tcb.2009.03.001
Crosstalk between histone modifications during the DNA damage response
resolves10.4161/cc.9.17.12884
H2AX post-translational modifications in the ionizing radiation response and homologous recombination
resolves10.1016/j.celrep.2013.01.029
Protein Phosphatase 2A Catalytic Subunit α Plays a MyD88-Dependent, Central Role in the Gene-Specific Regulation of Endotoxin Tolerance
resolves10.1021/ac010853p
Residue-specific Mass Signatures for the Efficient Detection of Protein Modifications by Mass Spectrometry
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