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Hypoxia upregulates Cxcl12 in hepatocytes by a complex mechanism involving hypoxia-inducible factors and transforming growth factor-β

https://doi.org/10.1016/j.cyto.2020.154986
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20/20 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

1 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 20 checked references that resolve
resolves10.1016/j.ajpath.2010.11.026
Bile Acids Induce Inflammatory Genes in Hepatocytes
resolves10.1242/jcs.00229
Making sense of latent TGFβ activation
resolves10.1016/j.taap.2011.02.005
Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia
resolves10.1016/j.tox.2006.05.016
Anticoagulation and inhibition of nitric oxide synthase influence hepatic hypoxia after monocrotaline exposure
resolves10.1111/j.1478-3231.2009.02015.x
Hypoxia‐inducible factor‐dependent production of profibrotic mediators by hypoxic hepatocytes
resolves10.1111/j.1478-3231.2010.02205.x
Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-β-dependent mechanisms
resolves10.1016/S0002-9440(10)64881-X
Hepatocyte Growth Factor and c-Met Inhibition by Hepatic Cell Hypoxia
resolves10.1152/ajpgi.00056.2016
VEGF-sdf1 recruitment of CXCR7<sup>+</sup> bone marrow progenitors of liver sinusoidal endothelial cells promotes rat liver regeneration
resolves10.1038/nature12681
Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis
resolves10.1002/hep.22890
Hepatic stellate cells express functional CXCR4
resolves10.1152/ajpgi.00193.2016
Stromal cell-derived factor-1 (SDF-1) as a target in liver diseases
resolves10.1053/j.gastro.2014.06.043
Roles for Chemokines in Liver Disease
resolves10.1152/ajpgi.90368.2008
Reduced liver fibrosis in hypoxia-inducible factor-1α-deficient mice
resolves10.1002/jcb.21759
Hypoxia stimulates the autocrine regulation of migration of vascular smooth muscle cells via HIF‐1α‐dependent expression of thrombospondin‐1
resolves10.1111/hepr.12411
Inhibition of the <scp>CXCL</scp>12/<scp>CXCR</scp>4 chemokine axis with <scp>AMD</scp>3100, a <scp>CXCR</scp>4 small molecule inhibitor, worsens murine hepatic injury
resolves10.1016/j.trecan.2016.10.016
Hypoxia-Inducible Factors: Master Regulators of Cancer Progression
resolves10.1016/j.bbrc.2009.07.115
HIF-1α is necessary to support gluconeogenesis during liver regeneration
resolves10.1002/eji.200324441
Involvement of the CXCL12/CXCR4 pathway in the advanced liver disease that is associated with hepatitis C virus or hepatitis B virus
resolves10.1161/CIRCRESAHA.109.197533
Inhibition of the SDF-1/CXCR4 Axis Attenuates Neonatal Hypoxia-Induced Pulmonary Hypertension
resolves10.2353/ajpath.2006.060211
Oval Cell Response in 2-Acetylaminofluorene/Partial Hepatectomy Rat Is Attenuated by Short Interfering RNA Targeted to Stromal Cell-Derived Factor-1
The 1 reference without a DOI — listed, not checked
no DOI — not checkedHypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1alpha-independent manner
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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