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Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex

https://doi.org/10.1016/j.devcel.2020.05.031

47/47 checkable references clean · checked 2026-07-22

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

1 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 47 checked references that resolve

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LYN Is a Mediator of Epithelial-Mesenchymal Transition and a Target of Dasatinib in Breast Cancer

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Role of YAP/TAZ in mechanotransduction

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Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis

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Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

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S897 phosphorylation of EphA2 is indispensable for EphA2-dependent nasopharyngeal carcinoma cell invasion, metastasis and stem properties

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EphA2 Mediates Ligand-Dependent Inhibition and Ligand-Independent Promotion of Cell Migration and Invasion via a Reciprocal Regulatory Loop with Akt

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Tissue mechanics promote IDH1-dependent HIF1α–tenascin C feedback to regulate glioblastoma aggression

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Ligand-Independent EPHA2 Signaling Drives the Adoption of a Targeted Therapy–Mediated Metastatic Melanoma Phenotype

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resolves10.1038/nrc2806

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Collagen reorganization at the tumor-stromal interface facilitates local invasion

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The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells

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Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis

resolves10.1038/onc.2017.5

Targeting Lyn regulates Snail family shuttling and inhibits metastasis

resolves10.1146/annurev.cellbio.13.1.513

CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES

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Dual Mechanisms of LYN Kinase Dysregulation Drive Aggressive Behavior in Breast Cancer Cells

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Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis

resolves10.1038/ncb3157

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

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Mechanosensing Controlled Directly by Tyrosine Kinases

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Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

resolves10.1101/gad.1602907

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resolves10.1248/bpb.b17-00446

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resolves10.1038/ncomms8679

Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2

The 1 reference without a DOI — listed, not checked

no DOI — not checkedEphA2 overexpression causes tumorigenesis of mammary epithelial cells

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