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Liraglutide protects cardiac microvascular endothelial cells against hypoxia/reoxygenation injury through the suppression of the SR-Ca2+–XO–ROS axis via activation of the GLP-1R/PI3K/Akt/survivin pathways
57/57 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 57 checked references that resolve
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No-reflow: the next challenge in treatment of ST-elevation acute myocardial infarction
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Donor Simvastatin Treatment Abolishes Rat Cardiac Allograft Ischemia/Reperfusion Injury and Chronic Rejection Through Microvascular Protection
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Free radical oxidation of brain proteins in accelerated senescence and its modulation by
<i>N</i>
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5-Year Prognostic Value of No-Reflow Phenomenon After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction
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Once-weekly dulaglutide versus once-daily liraglutide in metformin-treated patients with type 2 diabetes (AWARD-6): a randomised, open-label, phase 3, non-inferiority trial
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Effects of liraglutide on left ventricular function in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
resolves10.1007/s00380-014-0547-y
Hepatocyte growth factor suppresses hypoxia/reoxygenation-induced XO activation in cardiac microvascular endothelial cells
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Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications
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Alcohol‐induced blood–brain barrier dysfunction is mediated via inositol 1,4,5‐triphosphate receptor (IP<sub>3</sub>R)‐gated intracellular calcium release
resolves10.1016/j.cardiores.2006.09.015
Reoxygenation-induced Ca2+ rise is mediated via Ca2+ influx and Ca2+ release from the endoplasmic reticulum in cardiac endothelial cells☆
resolves10.1016/j.radonc.2011.10.011
Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature
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A PKC-β inhibitor protects against cardiac microvascular ischemia reperfusion injury in diabetic rats
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Bradykinin Protects Against Oxidative Stress–Induced Endothelial Cell Senescence
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Apoptosis of Endothelial Cells Precedes Myocyte Cell Apoptosis in Ischemia/Reperfusion Injury
resolves10.1038/ncpcardio0632
No-reflow phenomenon and prognosis in patients with acute myocardial infarction
resolves10.1016/j.freeradbiomed.2014.09.033
Exendin-4 protects adipose-derived mesenchymal stem cells from apoptosis induced by hydrogen peroxide through the PI3K/Akt–Sfrp2 pathways
resolves10.1016/j.freeradbiomed.2014.01.027
NADPH oxidase 4 promotes cardiac microvascular angiogenesis after hypoxia/reoxygenation in vitro
resolves10.1177/1479164114565629
Role of mitochondrial dysfunction in hyperglycaemia-induced coronary microvascular dysfunction: Protective role of resveratrol
resolves10.1016/0092-8674(81)90232-4
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Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation.
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Ischemia-reperfusion-induced calpain activation and SERCA2a degradation are attenuated by exercise training and calpain inhibition
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A review of efficacy and safety data regarding the use of liraglutide, a once-daily human glucagon-like peptide 1 analogue, in the treatment of type 2 diabetes mellitus
resolves10.1016/j.diabres.2012.11.009
Extraglycemic effects of glp-1-based therapeutics: Addressing metabolic and cardiovascular risks associated with type 2 diabetes
resolves10.1155/2011/946936
Survivin Selectively Modulates Genes Deregulated in Human Leukemia Stem Cells
resolves10.1002/jcp.21358
The anti‐apoptosis protein, survivin, mediates gastric epithelial cell cytoprotection against ethanol‐induced injury via activation of the p34<sup>cdc2</sup> cyclin‐dependent kinase
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The Expression of Genes Involved in Hepatocellular Carcinoma Chemoresistance Is Affected by Mitochondrial Genome Depletion
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Safety and efficacy of SITAgliptin plus GRanulocyte-colony-stimulating factor in patients suffering from Acute Myocardial Infarction (SITAGRAMI-Trial) — Rationale, design and first interim analysis
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Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure.
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Exendin-4 protects endothelial cells from lipoapoptosis by PKA, PI3K, eNOS, p38 MAPK, and JNK pathways
resolves10.1161/CIRCULATIONAHA.107.739938
Cardioprotective and Vasodilatory Actions of Glucagon-Like Peptide 1 Receptor Are Mediated Through Both Glucagon-Like Peptide 1 Receptor–Dependent and –Independent Pathways
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Glucagon-Like Peptide-1 Protects Against Cardiac Microvascular Injury in Diabetes via a cAMP/PKA/Rho-Dependent Mechanism
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Identification and Characterization of GLP-1 Receptor–Expressing Cells Using a New Transgenic Mouse Model
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GLP-1 Receptor Localization in Monkey and Human Tissue: Novel Distribution Revealed With Extensively Validated Monoclonal Antibody
resolves10.1016/j.bbrc.2009.12.075
Glucagon-like peptide-1 (GLP-1) inhibits advanced glycation end product (AGE)-induced up-regulation of VCAM-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression
resolves10.1152/ajpcell.00248.2012
Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a
resolves10.1016/S0140-6736(16)00082-9
Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial
resolves10.1016/j.cardfail.2009.01.013
Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial
resolves10.1007/s00204-013-1034-4
Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis
resolves10.1073/pnas.84.5.1404
Direct measurement of free radical generation following reperfusion of ischemic myocardium.
resolves10.1089/hum.1998.9.9-1381
Redox Gene Therapy Protects Human IB-3 Lung Epithelial Cells Against Ionizing Radiation-Induced Apoptosis
resolves10.1007/s10495-012-0766-6
Hypoxic preconditioning protects microvascular endothelial cells against hypoxia/reoxygenation injury by attenuating endoplasmic reticulum stress
resolves10.1002/jcb.20837
Mitochondrial mechanism of microvascular endothelial cells apoptosis in hyperhomocysteinemia
resolves10.1016/S0002-9440(10)64742-6
Control of Apoptosis during Angiogenesis by Survivin Expression in Endothelial Cells
resolves10.1016/j.vph.2015.03.002
Myricitrin attenuates endothelial cell apoptosis to prevent atherosclerosis: An insight into PI3K/Akt activation and STAT3 signaling pathways
resolves10.1007/s11010-011-1166-x
An essential role for the Id1/PI3K/Akt/NFkB/survivin signalling pathway in promoting the proliferation of endothelial progenitor cells in vitro
resolves10.1016/j.mvr.2009.08.006
Hyperglycemia attenuates angiogenic capability of survivin in endothelial cells
resolves10.1186/s12902-015-0005-6
The effects of treatment with liraglutide on atherothrombotic risk in obese young women with polycystic ovary syndrome and controls
resolves10.1111/j.1464-5491.2008.02484.x
Beneficial effects of once‐daily liraglutide, a human glucagon‐like peptide‐1 analogue, on cardiovascular risk biomarkers in patients with Type 2 diabetes
resolves10.1038/ijo.2013.149
Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults
The 2 references without a DOI — listed, not checked
no DOI — not checkedEffects of liraglutide on left ventricular function in patients with non-ST-segment elevation myocardial infarction
no DOI — not checkedLiraglutide promotes proliferation and migration of cardiac microvascular endothelial cells through PI3K/Akt and MAPK/ERK signaling pathways
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