Reference health
A comparative pilot study of oral diacerein and locally treated diacerein-loaded nanoparticles in a model of osteoarthritis
1 of 41 checkable references need attention · checked 2026-07-22
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
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References needing attention
marked retracted — notice via Crossref, record curated by Retraction Watch10.1002/art.23056
<i>Retracted:</i>
The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: A randomized, multicenter, double‐blind, placebo‐controlled study with primary end points at two months after the end of a three‐month treatment period
The 40 checked references that resolve
resolves10.1016/j.jddst.2019.101206
Doxorubicin-verapamil dual loaded PLGA nanoparticles for overcoming P-glycoprotein mediated resistance in cancer: Effect of verapamil concentration
resolves10.1016/j.semarthrit.2018.01.009
Efficacy and safety of repeated courses of hyaluronic acid injections for knee osteoarthritis: A systematic review
resolves10.1093/rheumatology/ken116
Diacerein has a weak effect on the catabolic pathway of human osteoarthritis synovial fibroblast--comparison to its effects on osteoarthritic chondrocytes
resolves10.1007/BF00301004
Reduction of tumor necrosis factor ? and interleukin-1? levels in human synovial tissue by interleukin-4 and glucocorticoid
resolves10.23736/S1973-9087.19.05633-8
Appropriateness of clinical criteria for the use of SYmptomatic Slow-Acting Drug for OsteoArthritis (SYSADOA). A Delphi Method Consensus initiative among experts in Italy
resolves10.1016/j.phrs.2008.11.004
Role of coxibs in the strategies for gastrointestinal protection in patients requiring chronic non-steroidal anti-inflammatory therapy
resolves10.1186/ar2444
Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling
resolves10.1172/JCI112350
Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.
resolves10.1093/rheumatology/kex496
Current status and future prospects for disease modification in osteoarthritis
resolves10.1053/joca.2001.0509
Characterization of infiltrating T cells and Th1/Th2-type cytokines in the synovium of patients with osteoarthritis
resolves10.1002/jor.21079
Effect of pro‐inflammatory and immunoregulatory cytokines on human tenocytes
resolves10.1007/s13770-018-0119-9
In Vitro Anti-Inflammation and Chondrogenic Differentiation Effects of Inclusion Nanocomplexes of Hyaluronic Acid-Beta Cyclodextrin and Simvastatin
resolves10.1136/ard.50.6.395
Interleukin-1, immune activation pathways, and different mechanisms in osteoarthritis and rheumatoid arthritis.
resolves10.1016/j.joca.2007.02.021
The efficacy, safety and carry-over effect of diacerein in the treatment of painful knee osteoarthritis: a randomised, double-blind, NSAID-controlled study
resolves10.1002/art.1780350507
The interleukin‐1 receptor in normal and osteoarthritic human articular chondrocytes. Identification as the type I receptor and analysis of binding kinetics and biologic function
resolves10.1177/1759720X09359104
Effects of diacerein at the molecular level in the osteoarthritis disease process
resolves10.1001/jama.2017.5283
Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis
resolves10.1007/s100670070029
Significance of Low mRNA Levels of Interleukin-4 and -10 in Mononuclear Cells of the Synovial Fluid of Patients with Rheumatoid Arthritis
resolves10.1001/jama.286.8.954
Risk of Cardiovascular Events Associated With Selective COX-2 Inhibitors
resolves10.1016/S0174-173X(86)80005-X
Characterization of a Specific Antiserum to Rabbit Stromelysin and Demonstration of the Synthesis of Collagenase and Stromelysin by Stimulated Rabbit Articular Chondrocytes
resolves10.1007/s40264-015-0266-z
Benefit–Risk Assessment of Diacerein in the Treatment of Osteoarthritis
resolves10.1007/s40266-016-0347-4
Diacerein: Benefits, Risks and Place in the Management of Osteoarthritis. An Opinion-Based Report from the ESCEO
resolves10.1002/1529-0131(200010)43:10<2339::AID-ANR23>3.0.CO;2-P
Efficacy and safety of diacerein in osteoarthritis of the knee: A double-blind, placebo-controlled trial
resolves10.2174/1381612821666150901100247
Particulate Systems Based on Poly(Lactic-co-Glycolic)Acid (pLGA) for Immunotherapy of Cancer
resolves10.1007/s11095-015-1748-5
PLGA-Based Nanoparticles: a Safe and Suitable Delivery Platform for Osteoarticular Pathologies
resolves10.1136/annrheumdis-2016-210815
EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis
resolves10.1016/S0006-2952(02)01485-5
Effects of rhein on human articular chondrocytes in alginate beads
resolves10.1100/2012/310745
Combined Effect of Subchondral Drilling and Hyaluronic Acid with/without Diacerein in Full-Thickness Articular Cartilage Lesion in Rabbits
resolves10.1016/j.joca.2013.05.018
Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration
resolves10.1016/j.joca.2012.04.002
IL-4 alone and in combination with IL-10 protects against blood-induced cartilage damage
The 4 references without a DOI — listed, not checked
no DOI — not checkedVariability in the prescription of drugs with uncertain effectiveness. The case of SYSADOA in the Basque Country. GMS
no DOI — not checkedRhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways
no DOI — not checked10.1016/j.ijpharm.2020.119249_b0145
no DOI — not checkedCurcumin-loaded poly lactic-co-glycolic acid nanoparticles effects on mono-iodoacetate -induced osteoarthritis in rats
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