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Management of Pulmonary Arterial Hypertension

https://doi.org/10.1016/j.jacc.2015.03.540
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1 of 106 checkable references need attention · checked 2026-08-10

At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.

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References needing attention

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The 105 checked references that resolve
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Guidelines for the diagnosis and treatment of pulmonary hypertension
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ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension
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Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review
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Definitions and Diagnosis of Pulmonary Hypertension
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Updated Clinical Classification of Pulmonary Hypertension
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High Frequency of <i>BMPR2</i> Exonic Deletions/Duplications in Familial Pulmonary Arterial Hypertension
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Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-β family
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Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia
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Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension
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A Novel Channelopathy in Pulmonary Arterial Hypertension
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Pulmonary arterial hypertension associated with fenfluramine exposure: report of 109 cases
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Pulmonary hypertension associated with benfluorex exposure
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Pulmonary Arterial Hypertension in Patients Treated by Dasatinib
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Pulmonary arterial hypertension in patients treated with interferon
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Pulmonary Arterial Hypertension in France
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Pulmonary Arterial Hypertension
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Screening for pulmonary arterial hypertension in patients with systemic sclerosis: Clinical characteristics at diagnosis and long‐term survival
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Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study
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Pulmonary Arterial Hypertension and HIV Infection
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Prevalence of HIV-Related Pulmonary Arterial Hypertension in the Current Antiretroviral Therapy Era
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An Evaluation of Long-term Survival From Time of Diagnosis in Pulmonary Arterial Hypertension From the REVEAL Registry
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Portopulmonary Hypertension
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Pulmonary arterial hypertension in adults born with a heart septal defect: the Euro Heart Survey on adult congenital heart disease
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Cardiopulmonary Manifestations of Hepatosplenic Schistosomiasis
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Survival in Schistosomiasis-Associated Pulmonary Arterial Hypertension
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The Role of Target Therapies in Schistosomiasis-Associated Pulmonary Arterial Hypertension
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Pulmonary veno-occlusive disease
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EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension
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Pulmonary Hypertension Due to Left Heart Diseases
resolves10.1016/j.jacc.2004.02.033
Pathologic assessment of vasculopathies in pulmonary hypertension
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Cellular and molecular pathobiology of pulmonary arterial hypertension
resolves10.1016/j.jacc.2013.10.025
Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension
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Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension
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Immune Dysregulation and Endothelial Dysfunction in Pulmonary Arterial Hypertension
resolves10.1183/09031936.00151313
Proinflammatory cytokine levels are linked to death in pulmonary arterial hypertension
resolves10.1016/j.jacc.2013.10.035
Genetics and Genomics of Pulmonary Arterial Hypertension
resolves10.7326/0003-4819-105-4-499
Primary Pulmonary Hypertension: Radiographic and Scintigraphic Patterns of Histologic Subtypes
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Survival in Patients With Idiopathic, Familial, and Anorexigen-Associated Pulmonary Arterial Hypertension in the Modern Management Era
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Validation of two predictive models for survival in pulmonary arterial hypertension
resolves10.1016/j.echo.2010.05.010
Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography
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Complications of Right Heart Catheterization Procedures in Patients With Pulmonary Hypertension in Experienced Centers
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Long-Term Response to Calcium Channel Blockers in Idiopathic Pulmonary Arterial Hypertension
resolves10.1161/CIRCHEARTFAILURE.109.930701
Exercise Hemodynamics Enhance Diagnosis of Early Heart Failure With Preserved Ejection Fraction
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Clinical Characteristics of Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction
resolves10.1016/j.echo.2007.10.003
Noninvasive Differentiation of Pulmonary Arterial and Venous Hypertension Using Conventional and Doppler Tissue Imaging Echocardiography
resolves10.1016/j.jcmg.2013.05.014
LA Volume by CMR Distinguishes Idiopathic From Pulmonary Hypertension Due to HFpEF
resolves10.1161/CIRCULATIONAHA.106.618397
Exercise and Respiratory Training Improve Exercise Capacity and Quality of Life in Patients With Severe Chronic Pulmonary Hypertension
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The Effect of High Doses of Calcium-Channel Blockers on Survival in Primary Pulmonary Hypertension
resolves10.1378/chest.112.3.714
The Effect of Anticoagulant Therapy in Primary and Anorectic Drug-Induced Pulmonary Hypertension
resolves10.1161/01.CIR.70.4.580
Primary pulmonary hypertension: natural history and the importance of thrombosis.
resolves10.1161/CIRCULATIONAHA.113.004526
Anticoagulation and Survival in Pulmonary Arterial Hypertension
resolves10.1164/ajrccm.159.6.9804054
Prostacyclin Synthase Expression Is Decreased in Lungs from Patients with Severe Pulmonary Hypertension
resolves10.1056/NEJM199602013340504
A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension
resolves10.1161/01.CIR.0000029100.82385.58
Survival in Primary Pulmonary Hypertension
resolves10.1016/S0735-1097(02)02012-0
Long-term intravenous epoprostenol infusion in primary pulmonary hypertension
resolves10.7326/0003-4819-132-6-200003210-00002
Continuous Intravenous Epoprostenol for Pulmonary Hypertension Due to the Scleroderma Spectrum of Disease
resolves10.1164/ajrccm.165.6.2106079
Continuous Subcutaneous Infusion of Treprostinil, a Prostacyclin Analogue, in Patients with Pulmonary Arterial Hypertension: A Double-blind, Randomized, Placebo-controlled Trial
resolves10.1016/j.jacc.2010.01.027
Addition of Inhaled Treprostinil to Oral Therapy for Pulmonary Arterial Hypertension
resolves10.1161/CIRCULATIONAHA.112.124388
Efficacy and Safety of Oral Treprostinil Monotherapy for the Treatment of Pulmonary Arterial Hypertension
resolves10.1378/chest.11-2212
Oral Treprostinil for the Treatment of Pulmonary Arterial Hypertension in Patients on Background Endothelin Receptor Antagonist and/or Phosphodiesterase Type 5 Inhibitor Therapy (The FREEDOM-C Study)
resolves10.1378/chest.12-2875
Oral Treprostinil for the Treatment of Pulmonary Arterial Hypertension in Patients Receiving Background Endothelin Receptor Antagonist and Phosphodiesterase Type 5 Inhibitor Therapy (The FREEDOM-C2 Study)
resolves10.1056/NEJMoa020204
Inhaled Iloprost for Severe Pulmonary Hypertension
resolves10.7326/0003-4819-114-6-464
Increased Plasma Endothelin-1 in Pulmonary Hypertension: Marker or Mediator of Disease?
resolves10.1056/NEJM199306173282402
Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension
resolves10.1378/chest.06-0682
Endothelin-1/Endothelin-3 Ratio
resolves10.1056/NEJMoa012212
Bosentan Therapy for Pulmonary Arterial Hypertension
resolves10.1016/S0140-6736(08)60919-8
Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial
resolves10.1161/CIRCULATIONAHA.106.630715
Bosentan Therapy in Patients With Eisenmenger Syndrome
resolves10.1161/CIRCULATIONAHA.107.742510
Ambrisentan for the Treatment of Pulmonary Arterial Hypertension
resolves10.1056/NEJMoa1213917
Macitentan and Morbidity and Mortality in Pulmonary Arterial Hypertension
resolves10.1056/NEJM199507273330403
Reduced Expression of Endothelial Nitric Oxide Synthase in the Lungs of Patients with Pulmonary Hypertension
resolves10.1056/NEJMoa050010
Sildenafil Citrate Therapy for Pulmonary Arterial Hypertension
resolves10.1161/CIRCULATIONAHA.108.839274
Tadalafil Therapy for Pulmonary Arterial Hypertension
resolves10.1183/09031936.00039808
First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension
resolves10.1161/CIRCULATIONAHA.110.981738
Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease
resolves10.1056/NEJMoa1209657
Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension
resolves10.1056/NEJMoa1209655
Riociguat for the Treatment of Pulmonary Arterial Hypertension
resolves10.1164/rccm.201104-0662CI
Intensive Care Unit Management of Patients with Severe Pulmonary Hypertension and Right Heart Failure
resolves10.1016/j.ejcts.2010.02.039
Long-term outcome of double-lung and heart–lung transplantation for pulmonary hypertension: a comparative retrospective study of 219 patients☆
resolves10.1055/s-0033-1356460
Management of Severe Pulmonary Arterial Hypertension
resolves10.1161/CIRCULATIONAHA.114.006974
Advances in Therapeutic Interventions for Patients With Pulmonary Arterial Hypertension
resolves10.1183/09031936.00072210
Effect of atrial septostomy on the survival of patients with severe pulmonary arterial hypertension
resolves10.1183/09031936.00116313
Upfront triple combination therapy in pulmonary arterial hypertension: a pilot study
resolves10.1016/j.jacc.2013.10.034
Treatment Goals of Pulmonary Hypertension
resolves10.1378/chest.14-0793
Pharmacologic Therapy for Pulmonary Arterial Hypertension in Adults
resolves10.1016/j.jacc.2013.10.030
The Fifth World Symposium on Pulmonary Hypertension
resolves10.1183/09031936.00137511
Selexipag: an oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension
resolves10.1161/CIRCULATIONAHA.112.000765
Imatinib Mesylate as Add-on Therapy for Pulmonary Arterial Hypertension
resolves10.1161/CIRCULATIONAHA.105.591321
Cross Talk Between Endothelial and Smooth Muscle Cells in Pulmonary Hypertension
resolves10.1253/circj.CJ-13-0443
Double-Blind, Placebo-Controlled Clinical Trial With a Rho-Kinase Inhibitor in Pulmonary Arterial Hypertension
resolves10.1002/art.23303
Immunosuppressive therapy in lupus‐ and mixed connective tissue disease–associated pulmonary arterial hypertension: A retrospective analysis of twenty‐three cases
resolves10.1161/hc0202.101974
Dichloroacetate, a Metabolic Modulator, Prevents and Reverses Chronic Hypoxic Pulmonary Hypertension in Rats
resolves10.1172/JCI65592
FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension
resolves10.1016/j.jacc.2006.12.037
Transplantation of Autologous Endothelial Progenitor Cells May Be Beneficial in Patients With Idiopathic Pulmonary Arterial Hypertension
resolves10.1164/rccm.201203-0411OC
Dysregulated Renin–Angiotensin–Aldosterone System Contributes to Pulmonary Arterial Hypertension
resolves10.1164/rccm.201003-0335OC
Adrenergic Receptor Blockade Reverses Right Heart Remodeling and Dysfunction in Pulmonary Hypertensive Rats
resolves10.1016/j.jacc.2013.05.075
Pulmonary Artery Denervation to Treat Pulmonary Arterial Hypertension
resolves10.1093/ejcts/ezu445
Palliative Potts shunt for the treatment of children with drug-refractory pulmonary arterial hypertension: updated data from the first 24 patients
resolves10.1016/j.healun.2013.01.1049
Transcatheter Potts shunt creation in patients with severe pulmonary arterial hypertension: Initial clinical experience
resolves10.1183/09031936.00089212
Outcomes of noncardiac, nonobstetric surgery in patients with PAH: an international prospective survey
resolves10.1155/2012/709407
Pulmonary Hypertension in Pregnancy: Critical Care Management
resolves10.1097/00000542-200506000-00012
Severe Pulmonary Hypertension during Pregnancy
resolves10.1183/09031936.00141211
Pregnancy outcomes in pulmonary arterial hypertension in the modern management era
resolves10.1016/j.athoracsur.2012.10.013
Use of the Impella 2.5 Microaxial Pump for Right Ventricular Support After Insertion of Heartmate II Left Ventricular Assist Device
resolves10.1001/jamainternmed.2013.319
Referral of Patients With Pulmonary Hypertension Diagnoses to Tertiary Pulmonary Hypertension Centers
The 5 references without a DOI — listed, not checked
no DOI — not checkedAminorex and pulmonary hypertension. A review
no DOI — not checkedMcLaughlin VV. Effect of selexipag on morbidity/mortality in pulmonary arterial hyertension: results of the GRIPHON study. Paper presented at: ACC.15; March 15, 2015; San Diego, CA.
no DOI — not checkedClinicalTrials.gov. Rituximab for treatment of systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH). 2014. Available at: https://clinicaltrials.gov/ct2/show/NCT01086540. Accessed March 15, 2015.
no DOI — not checkedClinicalTrials.gov. Dichloroacetate (DCA) for the treatment of pulmonary arterial hypertension. 2014. Available at: https://clinicaltrials.gov/ct2/show/NCT01083524. Accessed March 15, 2015.
no DOI — not checkedUse of Tandem Heart as a temporary hemodynamic support option for severe pulmonary artery hypertension complicated by cardiogenic shock
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