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The possible role of progranulin on anti-inflammatory effects of metformin in temporal lobe epilepsy

https://doi.org/10.1016/j.jchemneu.2020.101849
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1 of 39 checkable references need attention · checked 2026-07-23

At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.

4 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

References needing attention

marked retracted — notice via Crossref, record curated by Retraction Watch10.1007/s10735-019-09824-0
RETRACTED ARTICLE: Oligoprotective effect of metformin through the AMPK-dependent on restoration of mitochondrial hemostasis in the cuprizone-induced multiple sclerosis model
The 38 checked references that resolve
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Astrocytic expression of GFAP and serum levels of IL-1β and TNF-α in rats treated with different pain relievers
resolves10.1016/j.brainresbull.2016.02.005
Neuroprotective effects of metformin against Aβ-mediated inhibition of long-term potentiation in rats fed a high-fat diet
resolves10.3389/fncel.2014.00155
The inflammatory molecules IL-1β and HMGB1 can rapidly enhance focal seizure generation in a brain slice model of temporal lobe epilepsy
resolves10.1016/S0006-8993(02)03050-0
Inflammatory reactions in human medial temporal lobe epilepsy with hippocampal sclerosis
resolves10.1016/j.tins.2012.11.008
Glia and epilepsy: excitability and inflammation
resolves10.1096/fj.201601134R
Foxo4‐ and Stat3‐dependent IL‐10 production by progranulin in regulatory T cells restrains inflammatory arthritis
resolves10.3389/fneur.2017.00244
Role of Interleukin-10 in Acute Brain Injuries
resolves10.1038/s41598-017-03032-0
Rapamycin Attenuates Acute Seizure-induced Astrocyte Injury in Mice in Vivo
resolves10.1159/000026433
Cytokine Effects on Glutamate Uptake by Human Astrocytes
resolves10.2174/1570159X13666150205143555
Neuropharmacological Actions of Metformin in Stroke
resolves10.1093/brain/awv079
Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke
resolves10.1038/srep42791
Interleukin 10 inhibits pro-inflammatory cytokine responses and killing of Burkholderia pseudomallei
resolves10.3390/ijms18030490
Progranulin and Its Related MicroRNAs after Status Epilepticus: Possible Mechanisms of Neuroprotection
resolves10.1007/s11055-007-0036-1
Protective effects of interleukin-10 on the development of epileptiform activity evoked by transient episodes of hypoxia in rat hippocampal slices
resolves10.3389/fnagi.2018.00227
Evaluation of Metformin on Cognitive Improvement in Patients With Non-dementia Vascular Cognitive Impairment and Abnormal Glucose Metabolism
resolves10.1007/s11095-017-2199-y
Metformin – a Future Therapy for Neurodegenerative Diseases
resolves10.3389/fncel.2018.00458
The Interleukin-10 Family of Cytokines and Their Role in the CNS
resolves10.1007/s11011-017-0132-z
Evaluation of metformin effects in the chronic phase of spontaneous seizures in pilocarpine model of temporal lobe epilepsy
resolves10.1016/j.yebeh.2019.106893
Metformin and trimetazidine ameliorate diabetes-induced cognitive impediment in status epileptic rats
resolves10.1186/s12974-019-1549-6
Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis
resolves10.1016/j.npep.2019.05.003
2-Deoxyglucose protects hippocampal neurons against kainate-induced temporal lobe epilepsy by modulating monocyte-derived macrophages (mo-MΦ) and progranulin production in the hippocampus
resolves10.1186/s12974-016-0754-9
Metformin reduces morphine tolerance by inhibiting microglial-mediated neuroinflammation
resolves10.1016/j.neuroscience.2014.07.046
Neuroprotective effect of metformin in MPTP-induced Parkinson’s disease in mice
resolves10.1016/j.bbadis.2015.11.014
Reactive gliosis in the pathogenesis of CNS diseases
resolves10.3389/fnmol.2016.00031
Reduced miR-659-3p Levels Correlate with Progranulin Increase in Hypoxic Conditions: Implications for Frontotemporal Dementia
resolves10.1186/s13326-018-0192-y
Investigating the role of interleukin-1 beta and glutamate in inflammatory bowel disease and epilepsy using discovery browsing
resolves10.1038/nrn3898
Astrocyte barriers to neurotoxic inflammation
resolves10.1007/s11064-014-1504-y
Role for Pro-inflammatory Cytokines in Regulating Expression of GABA Transporter Type 1 and 3 in Specific Brain Regions of Kainic Acid-Induced Status Epilepticus
resolves10.1186/s12974-019-1452-1
Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures
resolves10.1016/j.neuroscience.2013.06.049
Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice
resolves10.1126/science.1199214
The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice
resolves10.1016/j.brainres.2011.11.063
Neuroprotective effects of progranulin in ischemic mice
resolves10.1016/j.brainresbull.2018.04.008
Neuroprotective effects of metformin on traumatic brain injury in rats associated with NF-κB and MAPK signaling pathway
resolves10.1111/j.1535-7511.2007.00165.x
New Roles for Interleukin-1 Beta in the Mechanisms of Epilepsy
resolves10.1046/j.1528-1157.43.s.5.14.x
Functional Role of Inflammatory Cytokines and Antiinflammatory Molecules in Seizures and Epileptogenesis
resolves10.1523/JNEUROSCI.23-25-08692.2003
Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases
resolves10.1155/2019/6234758
The Effect of Metformin in Experimentally Induced Animal Models of Epileptic Seizure
resolves10.1084/jem.20091568
Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
The 4 references without a DOI — listed, not checked
no DOI — not checkedNeuropathology of temporal lobe epilepsy
no DOI — not checkedInflammation and reactive oxygen species as disease modifiers in epilepsy
no DOI — not checkedDose-dependent anticonvulsant and protective effects of metformin in kainate induced temporal lobe epilepsy
no DOI — not checkedChanges of hs-CRP, S100B and NSE levels in serum and cerebrospinal fluid of children with epilepsy and their correlation with the nerve cell apoptosis
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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