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Chitosan-coated rosmarinic acid nanoemulsion nasal administration protects against LPS-induced memory deficit, neuroinflammation, and oxidative stress in Wistar rats

https://doi.org/10.1016/j.neuint.2020.104875
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Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

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The 33 checked references that resolve
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A natural scavenger of peroxynitrites, rosmarinic acid, protects against impairment of memory induced by Aβ25–35
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Orally administered rosmarinic acid is present as the conjugated and/or methylated forms in plasma, and is degraded and metabolized to conjugated forms of caffeic acid, ferulic acid and m-coumaric acid
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Glioprotective Effect of Chitosan-Coated Rosmarinic Acid Nanoemulsions Against Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Rat Astrocyte Primary Cultures
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Box-Behnken design optimization of mucoadhesive chitosan-coated nanoemulsions for rosmarinic acid nasal delivery—In vitro studies
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Sensitive ultra-fast liquid chromatography method for rosmarinic acid determination in Wistar rat’s plasma and brain
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A novel, simplified and stability-indicating high-throughput ultra-fast liquid chromatography method for the determination of rosmarinic acid in nanoemulsions, porcine skin and nasal mucosa
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Rosmarinic acid prevents against memory deficits in ischemic mice
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Rosmarinic acid exerts a neuroprotective effect in the kainate rat model of temporal lobe epilepsy: Underlying mechanisms
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Targeted delivery of rosmarinic acid across the blood–brain barrier for neuronal rescue using polyacrylamide-chitosan-poly(lactide- co -glycolide) nanoparticles with surface cross-reacting material 197 and apolipoprotein E
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<i>Perilla frutescens</i> var. <i>japonica</i> and rosmarinic acid improve amyloid-β<sub>25-35</sub> induced impairment of cognition and memory function
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The 3 references without a DOI — listed, not checked
no DOI — not checkedDevelopment, characterization and nasal delivery of rosmarinic acid-loaded solid lipid nanoparticles for the effective management of Huntington's disease
no DOI — not checkedNasal drug delivery – as an effective tool for brain targeting - a review
no DOI — not checkedA potential alternative against neurodegenerative diseases
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