Reference health

A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting

https://doi.org/10.1016/j.stem.2021.01.007
CiteStamped reference-health badge
70/70 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

1 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 70 checked references that resolve
resolves10.1128/MCB.22.8.2607-2619.2002
Conditional Disruption of the Peroxisome Proliferator-Activated Receptor γ Gene in Mice Results in Lowered Expression of ABCA1, ABCG1, and apoE in Macrophages and Reduced Cholesterol Efflux
resolves10.1242/dmm.003087
Dre recombinase, like Cre, is a highly efficient site-specific recombinase in <i>E. coli</i>, mammalian cells and mice
resolves10.1038/s41590-018-0276-y
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
resolves10.1038/s41580-019-0186-3
Unravelling cellular relationships during development and regeneration using genetic lineage tracing
resolves10.1172/JCI58050
Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice
resolves10.1038/ncb2696
Characterization of the adipocyte cellular lineage in vivo
resolves10.1016/j.cmet.2013.10.003
Weighing in on Adipocyte Precursors
resolves10.1016/j.cmet.2016.10.023
Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans
resolves10.1016/j.stem.2017.02.005
Pericytes or Mesenchymal Stem Cells: Is That the Question?
resolves10.1016/j.celrep.2019.12.046
Parallel Lineage-Tracing Studies Establish Fibroblasts as the Prevailing In Vivo Adipocyte Progenitor
resolves10.1016/j.cell.2018.09.009
Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting
resolves10.1038/nrm3198
Forming functional fat: a growing understanding of adipocyte differentiation
resolves10.1016/j.cell.2018.06.035
A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality
resolves10.1016/j.stem.2016.09.007
Monitoring Tissue Regeneration at Single-Cell Resolution
resolves10.1016/j.cmet.2011.02.005
Transcriptional Control of Adipose Lipid Handling by IRF4
resolves10.1161/CIRCULATIONAHA.117.029343
Cardiomyocyte Regeneration
resolves10.1038/nrg3724
Gene expression regulation mediated through reversible m6A RNA methylation
resolves10.1038/ki.2015.274
Inducible glomerular erythropoietin production in the adult kidney
resolves10.1016/j.cell.2007.10.004
Developmental Origin of Fat: Tracking Obesity to Its Source
resolves10.1016/j.stem.2017.04.010
Are Perivascular Adipocyte Progenitors Mural Cells or Adventitial Fibroblasts?
resolves10.1016/j.stem.2016.12.006
Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo
resolves10.1016/j.neuron.2016.08.021
Strategies and Tools for Combinatorial Targeting of GABAergic Neurons in Mouse Cerebral Cortex
resolves10.1172/JCI93868
Preexisting endothelial cells mediate cardiac neovascularization after injury
resolves10.1038/nm.4437
Enhancing the precision of genetic lineage tracing using dual recombinases
resolves10.1161/CIRCULATIONAHA.119.045566
Heart Regeneration by Endogenous Stem Cells and Cardiomyocyte Proliferation
resolves10.1093/nar/gkt1361
Binary recombinase systems for high-resolution conditional mutagenesis
resolves10.1016/S0092-8674(01)00336-1
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
resolves10.1038/nm.4429
UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis
resolves10.1038/ncb3122
Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity
resolves10.1007/978-1-60327-292-6_26
Essentials of Recombinase-Based Genetic Fate Mapping in Mice
resolves10.1038/nn2050
Redefining the serotonergic system by genetic lineage
resolves10.1016/j.celrep.2014.09.049
Independent Stem Cell Lineages Regulate Adipose Organogenesis and Adipose Homeostasis
resolves10.1016/j.devcel.2020.05.017
Adrenergic-Independent Signaling via CHRNA2 Regulates Beige Fat Activation
resolves10.1016/j.neuron.2009.07.010
Linking Genetically Defined Neurons to Behavior through a Broadly Applicable Silencing Allele
resolves10.1016/j.cell.2012.01.002
Lineage Tracing
resolves10.1073/pnas.89.14.6232
Targeted oncogene activation by site-specific recombination in transgenic mice.
resolves10.1016/j.cmet.2012.03.009
In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding
resolves10.1161/CIRCULATIONAHA.118.034250
Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases
resolves10.1016/j.devcel.2020.06.021
Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor Metastasis
resolves10.1038/cr.2017.117
Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis
resolves10.1038/s41588-019-0346-6
Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction
resolves10.1074/jbc.REV120.011631
Genetic lineage tracing with multiple DNA recombinases: A user's guide for conducting more precise cell fate mapping studies
resolves10.1016/j.cmet.2014.03.025
A Smooth Muscle-Like Origin for Beige Adipocytes
resolves10.1038/cr.2017.143
Endothelial-specific m6A modulates mouse hematopoietic stem and progenitor cell development via Notch signaling
resolves10.1038/nn.2467
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
resolves10.1016/j.neuron.2015.02.022
Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance
resolves10.1038/nm.4031
Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice
resolves10.1161/CIRCRESAHA.113.302564
Are Resident c-Kit <sup>+</sup> Cardiac Stem Cells Really All That Are Needed to Mend a Broken Heart?
resolves10.1016/j.cell.2020.06.021
CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling
resolves10.1126/science.aai8792
Regeneration of fat cells from myofibroblasts during wound healing
resolves10.1161/CIRCRESAHA.118.312981
Genetic Targeting of Organ-Specific Blood Vessels
resolves10.1242/dev.030007
Prox1 maintains muscle structure and growth in the developing heart
resolves10.1042/BCJ20190463
UCP1-independent thermogenesis
resolves10.1016/j.cell.2017.05.045
Dynamic RNA Modifications in Gene Expression Regulation
resolves10.1073/pnas.85.14.5166
Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.
resolves10.1093/nar/23.24.5080
A<i>cre</i>-transgenic mouse strain for the ubiquitous deletion of<i>loxP</i>-flanked gene segments including deletion in germ cells
resolves10.1038/76996
Hepatocyte migration during liver development requires Prox1
resolves10.1101/gad.1588407
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature
resolves10.1016/S1074-7613(01)00134-0
T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance
resolves10.1126/science.1156232
White Fat Progenitor Cells Reside in the Adipose Vasculature
resolves10.1038/cr.2013.83
Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries
resolves10.1161/CIRCRESAHA.116.305097
Cellular Origin and Developmental Program of Coronary Angiogenesis
resolves10.1242/dev.126.3.443
Transcription factors Mash-1 and Prox-1 delineate early steps in differentiation of neural stem cells in the developing central nervous system
resolves10.1016/j.cmet.2015.10.018
Pdgfrβ+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice
resolves10.1016/j.stem.2017.03.013
Do Adipocytes Emerge from Mural Progenitors?
resolves10.1038/nm.3324
Tracking adipogenesis during white adipose tissue development, expansion and regeneration
resolves10.1038/6844
Prox1 function is crucial for mouse lens-fibre elongation
resolves10.1161/CIRCRESAHA.116.308749
Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls
resolves10.1038/nature23883
m6A modulates haematopoietic stem and progenitor cell specification
resolves10.1016/j.ceb.2019.07.004
Dual genetic approaches for deciphering cell fate plasticity in vivo: more than double
The 1 reference without a DOI — listed, not checked
no DOI — not checkedInduction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-07-23 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.1016/j.stem.2021.01.007"><img src="https://citestamp.com/citestamped/10.1016/j.stem.2021.01.007/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.1016/j.stem.2021.01.007/badge.svg)](https://citestamp.com/citestamped/10.1016/j.stem.2021.01.007)