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Antiviral Monoclonal Antibodies: Can They Be More Than Simple Neutralizing Agents?

https://doi.org/10.1016/j.tim.2015.07.005
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The 94 checked references that resolve
resolves10.1038/nri2747
Strategies and challenges for the next generation of therapeutic antibodies
resolves10.4161/19420862.2015.988944
Antibodies to watch in 2015
resolves10.4161/onci.22789
Trial watch
resolves10.1371/journal.ppat.1000642
A Neutralizing Human Monoclonal Antibody Protects against Lethal Disease in a New Ferret Model of Acute Nipah Virus Infection
resolves10.1016/j.vaccine.2013.01.025
Monoclonal antibodies for prophylactic and therapeutic use against viral infections
resolves10.1146/annurev-immunol-032712-095916
Broadly Neutralizing Antiviral Antibodies
resolves10.1073/pnas.1220019110
Overcoming drug-resistant herpes simplex virus (HSV) infection by a humanized antibody
resolves10.1038/nbt1363
The growth and potential of human antiviral monoclonal antibody therapeutics
resolves10.1186/1741-7015-11-4
Clinical development of monoclonal antibody-based drugs in HIV and HCV diseases
resolves10.1038/nature13777
Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
resolves10.1155/2013/838491
Possible Future Monoclonal Antibody (mAb)-Based Therapy against Arbovirus Infections
resolves10.1371/journal.ppat.1003157
Therapeutic Efficacy of Antibodies Lacking FcγR against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies
resolves10.1038/ni.3058
A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus
resolves10.1016/j.cell.2015.01.031
Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus
resolves10.1371/journal.pone.0128823
Characterization of a Large Panel of Rabbit Monoclonal Antibodies against HIV-1 gp120 and Isolation of Novel Neutralizing Antibodies against the V3 Loop
resolves10.1128/JVI.03014-14
A Novel Humanized Antibody Neutralizes H5N1 Influenza Virus via Two Different Mechanisms
resolves10.1126/science.341.6151.1168
Bound for Glory
resolves10.1089/aid.2014.0235
Exploring the Potential of Monoclonal Antibody Therapeutics for HIV-1 Eradication
resolves10.1038/nature13601
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
resolves10.1126/science.1241144
Antibodies in HIV-1 Vaccine Development and Therapy
resolves10.1038/nri3516
Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning
resolves10.1038/nature12744
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys
resolves10.1126/scitranslmed.3009512
Broadly neutralizing antibodies abrogate established hepatitis C virus infection
resolves10.1097/COH.0b013e32832f0a89
Fc receptor-mediated antiviral antibodies
resolves10.1007/s11904-011-0105-5
Neutralizing Antibodies and Control of HIV: Moves and Countermoves
resolves10.3389/fimmu.2014.00289
Which Antibody Functions are Important for an HIV Vaccine?
resolves10.1016/j.virol.2012.10.007
New generation humanized mice for virus research: Comparative aspects and future prospects
resolves10.1016/j.jim.2014.02.011
Generation of improved humanized mouse models for human infectious diseases
resolves10.1084/jem.20141050
Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants
resolves10.1038/nri3311
Humanized mice for immune system investigation: progress, promise and challenges
resolves10.1128/JVI.64.4.1648-1656.1990
Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend murine leukemia virus
resolves10.1128/JVI.79.10.6272-6280.2005
Induction of Long-Term Protective Antiviral Endogenous Immune Response by Short Neutralizing Monoclonal Antibody Treatment
resolves10.1128/JVI.01970-07
Endogenous Cytotoxic T-Cell Response Contributes to the Long-Term Antiretroviral Protection Induced by a Short Period of Antibody-Based Immunotherapy of Neonatally Infected Mice
resolves10.1371/journal.ppat.1000948
A Crucial Role for Infected-Cell/Antibody Immune Complexes in the Enhancement of Endogenous Antiviral Immunity by Short Passive Immunotherapy
resolves10.1128/JVI.00568-10
Long-Lasting Protective Antiviral Immunity Induced by Passive Immunotherapies Requires both Neutralizing and Effector Functions of the Administered Monoclonal Antibody
resolves10.1182/blood-2012-06-432153
Control of regulatory T cells is necessary for vaccine-like effects of antiviral immunotherapy by monoclonal antibodies
resolves10.1128/JVI.78.11.5983-5995.2004
Passive Immunotherapy in Simian Immunodeficiency Virus-Infected Macaques Accelerates the Development of Neutralizing Antibodies
resolves10.1128/JVI.00145-09
Polyfunctional CD4 <sup>+</sup> T-Cell Induction in Neutralizing Antibody-Triggered Control of Simian Immunodeficiency Virus Infection
resolves10.1371/journal.pone.0000540
Post-Infection Immunodeficiency Virus Control by Neutralizing Antibodies
resolves10.1128/JVI.77.1.10-24.2003
Evidence for Antibody-Mediated Enhancement of Simian Immunodeficiency Virus (SIV) Gag Antigen Processing and Cross Presentation in SIV-Infected Rhesus Macaques
resolves10.1038/nm.2233
Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques
resolves10.1128/JVI.00049-13
Neutralizing Polyclonal IgG Present during Acute Infection Prevents Rapid Disease Onset in Simian-Human Immunodeficiency Virus SHIV <sub>SF162P3</sub> -Infected Infant Rhesus Macaques
resolves10.1038/nature14411
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
resolves10.1371/journal.pone.0018207
An Anti-HIV-1 V3 Loop Antibody Fully Protects Cross-Clade and Elicits T-Cell Immunity in Macaques Mucosally Challenged with an R5 Clade C SHIV
resolves10.1128/JVI.01503-14
Prophylaxis with a Respiratory Syncytial Virus (RSV) Anti-G Protein Monoclonal Antibody Shifts the Adaptive Immune Response to RSV rA2-line19F Infection from Th2 to Th1 in BALB/c Mice
resolves10.2217/imt.10.53
Therapeutic targeting of respiratory syncytial virus G-protein
resolves10.1128/JVI.00413-11
Multiple Functional Domains and Complexes of the Two Nonstructural Proteins of Human Respiratory Syncytial Virus Contribute to Interferon Suppression and Cellular Location
resolves10.1126/scitranslmed.3002901
A Neutralizing Human Monoclonal Antibody Protects African Green Monkeys from Hendra Virus Challenge
resolves10.1126/scitranslmed.3008929
Therapeutic Treatment of Nipah Virus Infection in Nonhuman Primates with a Neutralizing Human Monoclonal Antibody
resolves10.1016/j.antiviral.2013.06.012
A treatment for and vaccine against the deadly Hendra and Nipah viruses
resolves10.1016/j.coi.2013.12.005
Regulatory T cells in cancer immunotherapy
resolves10.1038/nrc3239
The blockade of immune checkpoints in cancer immunotherapy
resolves10.1016/j.cell.2015.03.030
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
resolves10.1073/pnas.1312772110
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
resolves10.1371/journal.ppat.1003856
Enhancing Virus-Specific Immunity In Vivo by Combining Therapeutic Vaccination and PD-L1 Blockade in Chronic Hepadnaviral Infection
resolves10.1371/journal.pone.0039179
PD-1 Blockage Reverses Immune Dysfunction and Hepatitis B Viral Persistence in a Mouse Animal Model
resolves10.1371/journal.pone.0077780
PD-1 Blockade in Chronically HIV-1-Infected Humanized Mice Suppresses Viral Loads
resolves10.1038/nature07662
Enhancing SIV-specific immunity in vivo by PD-1 blockade
resolves10.1371/journal.ppat.1003798
Combining Regulatory T Cell Depletion and Inhibitory Receptor Blockade Improves Reactivation of Exhausted Virus-Specific CD8+ T Cells and Efficiently Reduces Chronic Retroviral Loads
resolves10.1016/j.jhep.2014.07.005
Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation
resolves10.1089/aid.2012.0320
Augmentation of Hepatitis B Virus-Specific Cellular Immunity with Programmed Death Receptor-1/Programmed Death Receptor-L1 Blockade in Hepatitis B Virus and HIV/Hepatitis B Virus Coinfected Patients Treated with Adefovir
resolves10.1371/journal.pone.0063818
A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection
resolves10.4161/onci.27297
Trial Watch
resolves10.1111/j.1600-065X.2011.01062.x
OX40:OX40L axis: emerging targets for improving poxvirus‐based CD8<sup>+</sup> T‐cell vaccines against respiratory viruses
resolves10.4049/jimmunol.1300453
Targeting CD137 Enhances Vaccine-Elicited Anti–Respiratory Syncytial Virus CD8+ T Cell Responses in Aged Mice
resolves10.4049/jimmunol.1100077
4-1BB Signaling Synergizes with Programmed Death Ligand 1 Blockade To Augment CD8 T Cell Responses during Chronic Viral Infection
resolves10.3389/fimmu.2012.00332
Targeting 4-1BB (CD137) to enhance CD8 T cell responses with poxviruses and viral antigens
resolves10.1128/JVI.03309-13
Toll-Like Receptor 7/8 (TLR7/8) and TLR9 Agonists Cooperate To Enhance HIV-1 Envelope Antibody Responses in Rhesus Macaques
resolves10.1186/1479-5876-11-25
High efficacy of CpG-ODN, Cetuximab and Cisplatin combination for very advanced ovarian xenograft tumors
resolves10.1016/j.cell.2014.07.043
Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice
resolves10.1016/j.cell.2014.08.023
Broadly Neutralizing Anti-HIV-1 Antibodies Require Fc Effector Functions for In Vivo Activity
resolves10.1038/nm.3443
Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo
resolves10.1016/j.virol.2011.03.012
Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals
resolves10.1038/nature06106
Fc receptor but not complement binding is important in antibody protection against HIV
resolves10.1073/pnas.0508123103
Engineered antibody Fc variants with enhanced effector function
resolves10.1128/JVI.00491-12
A Nonfucosylated Variant of the anti-HIV-1 Monoclonal Antibody b12 Has Enhanced FcγRIIIa-Mediated Antiviral Activity <i>In Vitro</i> but Does Not Improve Protection against Mucosal SHIV Challenge in Macaques
resolves10.1093/jb/mvj157
Fucose Removal from Complex-Type Oligosaccharide Enhances the Antibody-Dependent Cellular Cytotoxicity of Single-Gene–Encoded Bispecific Antibody Comprising of Two Single-Chain Antibodies Linked to the Antibody Constant Region
resolves10.1016/j.jim.2005.08.009
IgG subclass-independent improvement of antibody-dependent cellular cytotoxicity by fucose removal from Asn297-linked oligosaccharides
resolves10.1073/pnas.1108360108
Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant
resolves10.1097/QAD.0000000000000444
Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function
resolves10.1172/JCI65708
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity
resolves10.2174/13892002113149990099
Neonatal Fc Receptor and its Role in the Absorption, Distribution, Metabolism and Excretion of Immunoglobulin G-Based Biotherapeutics
resolves10.3389/fimmu.2014.00408
The Role of FcRn in Antigen Presentation
resolves10.3389/fimmu.2014.00664
Regulation of Immune Responses by the Neonatal Fc Receptor and Its Therapeutic Implications
resolves10.1038/nature13612
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
resolves10.1097/QAD.0b013e32835cb720
Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to ‘protective’ human leukocyte antigen-B alleles in HIV controllers
resolves10.1126/scitranslmed.3007736
Polyfunctional Fc-Effector Profiles Mediated by IgG Subclass Selection Distinguish RV144 and VAX003 Vaccines
resolves10.1126/scitranslmed.3007730
Vaccine-Induced Env V1-V2 IgG3 Correlates with Lower HIV-1 Infection Risk and Declines Soon After Vaccination
resolves10.1371/journal.pone.0087572
Vaccine-Induced IgG Antibodies to V1V2 Regions of Multiple HIV-1 Subtypes Correlate with Decreased Risk of HIV-1 Infection
resolves10.3109/10428194.2012.762512
Correlation of Fc-γ RIIA polymorphisms with latent Epstein–Barr virus infection and latent membrane protein 1 expression in patients with low grade B-cell lymphomas
resolves10.1097/COH.0000000000000051
The role of Fc receptors in HIV infection and vaccine efficacy
resolves10.1172/JCI75539
FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial
resolves10.1371/journal.ppat.1001284
Innate Sensing of HIV-Infected Cells
resolves10.1002/hep.22337
Hepatitis C virus–infected hepatocytes extrinsically modulate dendritic cell maturation to activate T cells and natural killer cells†
The 3 references without a DOI — listed, not checked
no DOI — not checkedAntibodies in infectious diseases: polyclonals, monoclonals and niche biotechnology
no DOI — not checkedOf mice and men: the need for humanized mouse models to study human IgG activity in vivo
no DOI — not checkedhumanized mice to study FcgammaR function
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