Reference health
Bilirubin, a new therapeutic for kidney transplant?
1 of 85 checkable references need attention · checked 2026-07-23
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
16 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
References needing attention
marked retracted — notice via Crossref, record curated by Retraction Watch10.1002/oby.20559
<i>Retracted:</i> Increased HO‐1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21
The 84 checked references that resolve
resolves10.1053/j.ajkd.2013.03.022
Comparison of Life Participation Activities Among Adults Treated by Hemodialysis, Peritoneal Dialysis, and Kidney Transplantation: A Systematic Review
resolves10.1074/jbc.M116.731703
Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α
resolves10.1016/j.mehy.2016.08.013
Does bilirubin prevent hepatic steatosis through activation of the PPARα nuclear receptor?
resolves10.1152/ajprenal.00039.2014
Circulating bilirubin and defense against kidney disease and cardiovascular mortality: mechanisms contributing to protection in clinical investigations
resolves10.18632/oncotarget.12277
Glucuronidation and UGT isozymes in bladder: new targets for the treatment of uroepithelial carcinomas?
resolves10.4049/jimmunol.181.3.1887
Bilirubin Possesses Powerful Immunomodulatory Activity and Suppresses Experimental Autoimmune Encephalomyelitis
resolves10.1007/BF02088574
Intracellular accumulation of unconjugated bilirubin inhibits phytohemagglutinin-induced proliferation and interleukin-2 production of human lymphocytes
resolves10.2165/00063030-200115100-00003
Role of Anti???Interleukin-2 Receptor Antibodies in Kidney Transplantation
resolves10.1111/ctr.12346
Genetic polymorphisms in <i><scp>IL</scp>‐2</i>,<i><scp>IL</scp>‐10</i>,<i><scp>TGF</scp>‐</i>β<i>1</i>, and <i><scp>IL</scp>‐2<scp>RB</scp></i> and acute rejection in renal transplant patients
resolves10.1089/ars.2007.1807
Therapeutic Applications of Bilirubin and Biliverdin in Transplantation
resolves10.1111/ced.13289
Antioxidant status of serum bilirubin, uric acid and albumin in pemphigus vulgaris
resolves10.1152/ajprenal.00278.2004
The hyperbilirubinemic Gunn rat is resistant to the pressor effects of angiotensin II
resolves10.1016/j.atherosclerosis.2014.12.042
Bilirubin, platelet activation and heart disease: A missing link to cardiovascular protection in Gilbert's syndrome?
resolves10.1097/TP.0b013e3182100f3a
Effect of Obesity on the Outcome of Kidney Transplantation: A 20-Year Follow-Up
resolves10.1016/j.transproceed.2015.10.064
Early Weight Gain After Transplantation Can Cause Adverse Effect on Transplant Kidney Function
resolves10.1038/ki.2011.114
Higher recipient body mass index is associated with post-transplant delayed kidney graft function
resolves10.1186/s12916-015-0340-5
Body mass index and outcome in renal transplant recipients: a systematic review and meta-analysis
resolves10.1016/j.metabol.2009.04.003
Acute effect of weight loss on levels of total bilirubin in obese, cardiovascular high-risk patients: an analysis from the lead-in period of the Sibutramine Cardiovascular Outcome trial
resolves10.1210/en.2013-1667
Bilirubin Increases Insulin Sensitivity in Leptin-Receptor Deficient and Diet-Induced Obese Mice Through Suppression of ER Stress and Chronic Inflammation
resolves10.1038/srep09886
Bilirubin Increases Insulin Sensitivity by Regulating Cholesterol Metabolism, Adipokines and PPARγ Levels
resolves10.1016/j.biomaterials.2017.04.029
PEGylated bilirubin nanoparticle as an anti-oxidative and anti-inflammatory demulcent in pancreatic islet xenotransplantation
resolves10.1016/j.clinbiochem.2015.11.002
Oxidative stress is associated with weight gain in recipients at 12-months following kidney transplantation
resolves10.1172/JCI915
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.
resolves10.2217/bmm.12.4
Gilbert Syndrome: The
<i>UGT1A1</i>
*28 Promoter Polymorphism as a Biomarker of Multifactorial Diseases and Drug Metabolism
resolves10.1016/j.atherosclerosis.2008.01.001
Gilbert syndrome, UGT1A1*28 allele, and cardiovascular disease risk: Possible protective effects and therapeutic applications of bilirubin
resolves10.1542/peds.2008-3087
Variants in the <i>UGT1A1</i> Gene and the Risk of Pediatric Nonalcoholic Fatty Liver Disease
resolves10.3350/cmh.2012.18.4.357
Elevated serum bilirubin levels are inversely associated with nonalcoholic fatty liver disease
resolves10.3350/cmh.2012.18.4.383
Serum bilirubin levels are inversely associated with nonalcoholic fatty liver disease
resolves10.1016/j.numecd.2011.03.001
Relationships between serum total bilirubin levels and metabolic syndrome in Korean adults
resolves10.1111/j.1753-0407.2011.00138.x
Low serum total bilirubin concentrations are associated with increased prevalence of metabolic syndrome in Chinese
resolves10.1152/ajpendo.00396.2016
Mice with hyperbilirubinemia due to Gilbert’s syndrome polymorphism are resistant to hepatic steatosis by decreased serine 73 phosphorylation of PPARα
resolves10.1093/ndt/gfr613
High-fat diet-induced renal cell apoptosis and oxidative stress in spontaneously hypertensive rat are ameliorated by fenofibrate through the PPARα–FoxO3a–PGC-1α pathway
resolves10.1093/ndt/gfp258
Peroxisome proliferator-activated receptor alpha plays a crucial role in L-carnitine anti-apoptosis effect in renal tubular cells
resolves10.1046/j.1523-1755.2000.00937.x
Endothelial dysfunction in renal transplant recipients maintained on cyclosporine
resolves10.1038/ki.1994.332
Role of nitric oxide in renal hemodynamic abnormalities of cyclosporin nephrotoxicity
resolves10.1097/01.hjh.0000242412.88653.f2
Nitric oxide/cytochrome P450 interactions in cyclosporin A-induced effects in the rat
resolves10.1152/ajpregu.00316.2010
Moderate hyperbilirubinemia improves renal hemodynamics in ANG II-dependent hypertension
resolves10.1152/ajpregu.90889.2008
Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice
resolves10.1096/fj.04-2368fje
Bilirubin decreases NOS2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in rats
resolves10.1038/ki.2010.265
Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase
resolves10.1161/01.RES.74.6.1141
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
resolves10.1161/hh0901.089987
Role of NADPH Oxidase in the Vascular Hypertrophic and Oxidative Stress Response to Angiotensin II in Mice
resolves10.1161/01.HYP.0000101968.09376.79
Role of Superoxide in Modulating the Renal Effects of Angiotensin II
resolves10.1097/00004872-200403000-00016
Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice
resolves10.1161/01.ATV.0000148405.18071.6a
Bilirubin From Heme Oxygenase-1 Attenuates Vascular Endothelial Activation and Dysfunction
resolves10.1038/hr.2015.74
Bilirubin exerts pro-angiogenic property through Akt-eNOS-dependent pathway
resolves10.1186/1471-2369-12-29
Relationship of serum bilirubin concentration to kidney function and 24-hour urine protein in Korean adults
resolves10.1016/j.atherosclerosis.2017.09.001
Relationship between serum total bilirubin levels and mortality in uremia patients undergoing long-term hemodialysis: A nationwide cohort study
resolves10.1093/ajh/hpt038
Antihypertensive Actions of Moderate Hyperbilirubinemia: Role of Superoxide Inhibition
resolves10.1177/0960327112454891
Effects of fenofibrate, a PPAR-α ligand, on the haemodynamics of glycerol-induced renal failure in rats
resolves10.1152/ajprenal.00004.2007
Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese rats
resolves10.1152/physrev.00021.2001
<i>P</i>-450 Metabolites of Arachidonic Acid in the Control of Cardiovascular Function
resolves10.1007/s00109-009-0491-y
The interaction between ischemia–reperfusion and immune responses in the kidney
resolves10.1097/01.TP.0000069835.95442.9F
ACTIVATION OF MITOCHONDRIAL APOPTOTIC PATHWAYS IN HUMAN RENAL ALLOGRAFTS AFTER ISCHEMIA-REPERFUSION INJURY
resolves10.1016/j.freeradbiomed.2015.05.031
Bilirubin scavenges chloramines and inhibits myeloperoxidase-induced protein/lipid oxidation in physiologically relevant hyperbilirubinemic serum
resolves10.1038/srep15482
Endogenously elevated bilirubin modulates kidney function and protects from circulating oxidative stress in a rat model of adenine-induced kidney failure
resolves10.1161/CIRCULATIONAHA.112.105775
Hyperbilirubinemia, Augmentation of Endothelial Function, and Decrease in Oxidative Stress in Gilbert Syndrome
resolves10.1152/ajprenal.00215.2004
Protective effects of exogenous bilirubin on ischemia-reperfusion injury in the isolated, perfused rat kidney
resolves10.1111/j.1432-2277.2012.01515.x
Plasma bilirubin and late graft failure in renal transplant recipients
resolves10.1002/hep.20334
Bilirubin inhibits iNOS expression and NO production in response to endotoxin in rats
resolves10.1016/S0041-1345(00)01368-3
Examination of serum amyloid a protein in kidney transplant patients
resolves10.1136/bmj.288.6414.360
Measurement of serum amyloid A protein concentrations as test of renal allograft rejection in patients with initially non-functioning grafts.
resolves10.1186/1475-2840-12-166
High sensitive C-reactive protein and serum amyloid A are inversely related to serum bilirubin: effect-modification by metabolic syndrome
resolves10.1042/CS20120661
Protection from age-related increase in lipid biomarkers and inflammation contributes to cardiovascular protection in Gilbert's syndrome
resolves10.1016/j.tvjl.2016.07.002
Serum biochemistry profile, inflammatory cytokines, adipokines and cardiovascular findings in obese dogs
resolves10.1016/j.transproceed.2007.02.023
Serum C-Reactive Protein Surge in Renal Transplant Recipients: Link With Allograft Survival
resolves10.1016/j.biocel.2013.09.014
The molecular basis for the immunomodulatory activities of unconjugated bilirubin
resolves10.1096/fj.07-8472com
Heme oxygenase‐1, carbon monoxide, and bilirubin induce tolerance in recipients toward islet allografts by modulating T regulatory cells
resolves10.1097/00007890-199304000-00017
TUMOR NECROSIS FACTOR ALPHA IN HUMAN KIDNEY TRANSPLANT REJECTION—ANALYSIS BY IN SITU HYBRIDIZATION
resolves10.1084/jem.175.1.81
Tumor necrosis factor production during human renal allograft rejection is associated with depression of plasma protein C and free protein S levels and decreased intragraft thrombomodulin expression.
The 16 references without a DOI — listed, not checked
no DOI — not checkedThe level of IL-2 and IL-6 in stimulated peripheral lymphocyte supernatants of kidney transplant recipients can predict acute renal allograft rejection
no DOI — not checkedBilirubin effect on endothelial adhesion molecules expression is mediated by the NF-kappaB signaling pathway
no DOI — not checkedSerum bilirubin affects graft outcomes through UDP-glucuronosyltransferase sequence variation in kidney transplantation
no DOI — not checkedInterplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity
no DOI — not checkedHigh Total bilirubin as a protective factor for diabetes mellitus: an analysis of NHANES data from 1999 - 2006
no DOI — not checked10.1016/j.trre.2018.06.003_bb0215
no DOI — not checkedThe presence of anti-angiotensin II Type-1 receptor antibodies adversely affect kidney graft outcomes
no DOI — not checkedEffects of ANG II, ETA, and TxA2 receptor antagonists on cyclosporin A renal vasoconstriction
no DOI — not checkedThe role for reactive oxygen species in cyclosporin A induced nephrotoxicity in rats
no DOI — not checkedRole of reactive oxygen formation in the cyclosporin-A-mediated impairment of renal functions
no DOI — not checkedMice with hyperbilirubinemia due to Gilbert's syndrome polymorphism are resistant to hepatic steatosis by decreased serine 73 phosphorylation of PPARalpha
no DOI — not checkedOxidative stress in kidney transplantation: causes, consequences, and potential treatment
no DOI — not checkedC-reactive protein and early diagnosis of kidney transplant rejection
no DOI — not checkedThe diagnostic capacity of serum amyloid A protein for early recognition of kidney allograft rejection
no DOI — not checkedObstetric obesity is associated with neonatal hyperbilirubinemia with high prevalence in native Hawaiians and Pacific Island women
no DOI — not checkedEvaluation of serum tumor necrosis factor alpha and its correlation with histology in chronic kidney disease, stable renal transplant and rejection cases
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