Reference health

Occurrence and fate of the antidiabetic drug metformin and its metabolite guanylurea in the environment and during drinking water treatment

https://doi.org/10.1016/j.watres.2012.06.019
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24/24 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

15 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 24 checked references that resolve
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Cytotoxicity of pharmaceuticals found in aquatic systems: Comparison of PLHC-1 and RTG-2 fish cell lines
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Liquid chromatographic/electrospray ionization mass spectrometric identification of the oxidation end‐products of metformin in aqueous solutions
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Approach for detecting mutagenicity of biodegraded and ozonated pharmaceuticals, metabolites and transformation products from a drinking water perspective
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Rate constants for reaction of hydroxyl radicals with several drinking water contaminants
resolves10.1080/10826076.2010.519242
DETERMINATION OF METFORMIN IN CULTIVATED PLANT SPECIES AND SOIL BY LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY
resolves10.1021/es025896h
Oxidation of Pharmaceuticals during Ozonation and Advanced Oxidation Processes
resolves10.1111/j.1432-1033.2004.04438.x
Radical‐induced oxidation of metformin
resolves10.1021/es980712d
Metabolism Studies of Phenylsulfonamides Relevant for Water Works
resolves10.1016/S0956-053X(99)00003-3
Detection of polar organic substances relevant for drinking water
resolves10.1021/es011055j
Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000:  A National Reconnaissance
resolves10.1002/kin.550270610
Rate constants for some reactions of free radicals with haloacetates in aqueous solution
resolves10.1007/s00128-010-9990-3
Development and Application of a Model to Estimate Wastewater Treatment Plant Prescription Pharmaceutical Influent Loadings and Concentrations
resolves10.1007/BF00562061
Pharmacokinetics of metformin after intravenous and oral administration to man
resolves10.1021/ac9008012
Water Analysis: Emerging Contaminants and Current Issues
resolves10.1021/ac200915r
Water Analysis: Emerging Contaminants and Current Issues
resolves10.1039/b909311g
Occurrence of the antidiabetic drug metformin in sewage and surface waters in Germany
resolves10.1016/j.watres.2010.04.005
Performance of conventional multi-barrier drinking water treatment plants for the removal of four artificial sweeteners
resolves10.1071/EN05036
Removal of Iodinated X-Ray Contrast Media During Drinking Water Treatment
resolves10.1016/j.chemosphere.2011.06.057
Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea
resolves10.1007/s00216-010-4101-1
Optimization and validation of a hydrophilic interaction liquid chromatography–tandem mass spectrometry method for the determination of 13 top-prescribed pharmaceuticals in influent wastewater
resolves10.1016/S0043-1354(02)00457-8
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resolves10.1016/j.envpol.2011.04.033
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no DOI — not checkedEN ISO 7393-2, 2000. Water Quality — Determination of Free Chlorine and Total Chlorine — Part 2: Colorimetric Method Using N, N-diethyl-1,4-phenylenediamine for Routine Control Purposes. ISO 7393-2:1985.
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no DOI — not checkedRemoval of organic micropollutants by activated carbon
no DOI — not checkedHappel, O., Graf, C., Mertineit, S., Brauch, H.-J., 2009. Small scale filter test with activated carbon for the assessment of the removability of organic trace pollutants in drinking water production. In: Conference Proceedings of the Annual Conference of the Water Chemical Society (Branch of the German Chemical Society), May 18–20, 2009 (Stralsund, Germany), pp. 202–206.
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no DOI — not checkedDevelopment of a standardized testfilter for the determination of microbial degradability of single compounds
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no DOI — not checkedMarcus, P., 2005. Development and validation of a rapid laboratory test for assessment of the adsorbability of organic single substances onto activated carbon. Thesis, Technical University Dresden (in German).
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no DOI — not checkedWHO, 2012. http://www.whocc.no/atcddd/ (accessed 31.01.12).
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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