Reference health
Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge
35/35 checkable references clean · checked 2026-07-22
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
4 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 35 checked references that resolve
resolves10.1016/j.jneuroim.2008.06.011
Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration
resolves10.1111/j.1742-7843.2011.00824.x
Lipopolysaccharide‐Induced Sickness Behaviour Evaluated in Different Models of Anxiety and Innate Fear in Rats
resolves10.1097/00004714-200202000-00014
Increased Depressive Ratings in Patients With Hepatitis C Receiving Interferon-α–Based Immunotherapy Are Related to Interferon-α–Induced Changes in the Serotonergic System
resolves10.1016/j.bbr.2009.03.013
L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning
resolves10.1046/j.1471-4159.1996.67020692.x
Kynurenine Disposition in Blood and Brain of Mice: Effects of Selective Inhibitors of Kynurenine Hydroxylase and of Kynureninase
resolves10.1038/nrn2297
From inflammation to sickness and depression: when the immune system subjugates the brain
resolves10.1016/j.psyneuen.2010.09.012
Inflammation-associated depression: From serotonin to kynurenine
resolves10.1016/j.biopsych.2010.06.010
Inflammation-Induced Anhedonia: Endotoxin Reduces Ventral Striatum Responses to Reward
resolves10.1016/j.biopsych.2005.05.001
Mood Disorders in the Medically Ill: Scientific Review and Recommendations
resolves10.1016/j.psyneuen.2007.03.005
Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior
resolves10.1186/1742-2094-7-43
Central Administration of Lipopolysaccharide Induces Depressive-like Behavior in Vivo and Activates Brain Indoleamine 2,3 Dioxygenase In Murine Organotypic Hippocampal Slice Cultures
resolves10.1038/sj.npp.1301649
Aging Exacerbates Depressive-like Behavior in Mice in Response to Activation of the Peripheral Innate Immune System
resolves10.1371/journal.pone.0028330
Dose-Dependent Effects of Endotoxin on Neurobehavioral Functions in Humans
resolves10.1016/j.biopsych.2009.03.015
Inflammation Causes Mood Changes Through Alterations in Subgenual Cingulate Activity and Mesolimbic Connectivity
resolves10.1186/1742-2094-5-15
Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
resolves10.1016/j.febslet.2007.02.073
Differential regulation of indoleamine 2,3‐dioxygenase by lipopolysaccharide and interferon gamma in murine bone marrow derived dendritic cells
resolves10.1186/1756-6606-2-8
Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice
resolves10.1016/j.pbb.2010.12.008
Evidence for a key role of the peripheral kynurenine pathway in the modulation of anxiety- and depression-like behaviours in mice: Focus on individual differences
resolves10.1016/S0024-3205(02)01853-2
Depressive and anxiety symptoms in the early puerperium are related to increased degradation of tryptophan into kynurenine, a phenomenon which is related to immune activation
resolves10.1016/j.bbi.2008.04.001
Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior
resolves10.1523/JNEUROSCI.5032-08.2009
Interferon-γ and Tumor Necrosis Factor-α Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guérin
resolves10.4049/jimmunol.0802722
Induction of IDO by Bacille Calmette-Guérin Is Responsible for Development of Murine Depressive-Like Behavior
resolves10.1038/sj.mp.4002148
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice
resolves10.1016/0006-3223(94)91189-4
Kynurenine in blood plasma and DST in patients with endogenous anxiety and endogenous depression
resolves10.1038/npp.2010.39
Reduction of Endogenous Kynurenic Acid Formation Enhances Extracellular Glutamate, Hippocampal Plasticity, and Cognitive Behavior
resolves10.1038/mp.2009.116
CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression
resolves10.1016/j.pbb.2007.02.010
Effects of interleukin-1β and lipopolysaccharide on behavior of mice in the elevated plus-maze and open field tests
resolves10.1016/j.bbi.2009.06.152
LPS-induced indoleamine 2,3-dioxygenase is regulated in an interferon-γ-independent manner by a JNK signaling pathway in primary murine microglia
resolves10.1038/nm.2092
Kynurenine is an endothelium-derived relaxing factor produced during inflammation
resolves10.1016/j.cell.2011.05.020
Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration
The 4 references without a DOI — listed, not checked
no DOI — not checkedAcute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine
no DOI — not checkedLipopolysaccharide induces fever and depresses locomotor activity in unrestrained mice
no DOI — not checkedCoping strategies and psychological morbidity in family carers of people with dementia: a systematic review and meta-analysis
no DOI — not checkedAssociation of a polymorphism in the indoleamine-2,3-dioxygenase gene and interferon-alpha-induced depression in patients with chronic hepatitis C
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