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TAS-102 with or without bevacizumab in patients with chemorefractory metastatic colorectal cancer: an investigator-initiated, open-label, randomised, phase 2 trial

https://doi.org/10.1016/s1470-2045(19)30827-7
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17/17 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

3 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 17 checked references that resolve
resolves10.3322/caac.21492
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
resolves10.1093/annonc/mdw235
ESMO consensus guidelines for the management of patients with metastatic colorectal cancer
resolves10.1016/j.ctrv.2014.02.006
A systematic review of salvage therapy to patients with metastatic colorectal cancer previously treated with fluorouracil, oxaliplatin and irinotecan +/− targeted therapy
resolves10.1016/S1470-2045(12)70345-5
TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial
resolves10.1056/NEJMoa1414325
Randomized Trial of TAS-102 for Refractory Metastatic Colorectal Cancer
resolves10.1200/JCO.2017.74.3245
Results of a Randomized, Double-Blind, Placebo-Controlled, Phase III Trial of Trifluridine/Tipiracil (TAS-102) Monotherapy in Asian Patients With Previously Treated Metastatic Colorectal Cancer: The TERRA Study
resolves10.1016/S0140-6736(12)61900-X
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial
resolves10.1016/S1470-2045(15)70156-7
Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial
resolves10.1080/0284186X.2019.1605192
A systematic review of observational studies of trifluridine/tipiracil (TAS-102) for metastatic colorectal cancer
resolves10.2217/fon-2018-0147
Trifluridine/Tipiracil: An Emerging Strategy for the Management of Gastrointestinal Cancers
resolves10.1016/j.ejca.2017.10.009
The subgroups of the phase III RECOURSE trial of trifluridine/tipiracil (TAS-102) versus placebo with best supportive care in patients with metastatic colorectal cancer
resolves10.1136/esmoopen-2017-000261
Proxies of quality of life in metastatic colorectal cancer: analyses in the RECOURSE trial
resolves10.1016/S1470-2045(17)30425-4
TAS-102 plus bevacizumab for patients with metastatic colorectal cancer refractory to standard therapies (C-TASK FORCE): an investigator-initiated, open-label, single-arm, multicentre, phase 1/2 study
resolves10.1016/S1470-2045(13)70154-2
Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial
resolves10.1016/S0140-6736(14)62004-3
Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group
resolves10.1016/j.ejca.2018.10.009
Efficacy of bevacizumab in first-line treatment of metastatic colorectal cancer: A systematic review and meta-analysis
resolves10.1016/j.jgo.2015.07.002
Chemotherapy in the oldest old: The feasibility of delivering cytotoxic therapy to patients 80years old and older
The 3 references without a DOI — listed, not checked
no DOI — not checkedEfficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, together with bevacizumab, cetuximab, or panitumumab on human colorectal cancer xenografts
no DOI — not checkedThe role of angiogenesis inhibitors re-challenge in colorectal cancer previously treated with bevacizumab: a meta-analysis of randomized controlled trials
no DOI — not checkedPhase II study evaluating trifluridine/tipiracil+bevacizumab and capecitabine+bevacizumab in first-line unresectable metastatic colorectal cancer (mCRC) patients who are non-eligible for intensive therapy (TASCO1): results of the primary analysis
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

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