Reference health

Epigenetic Optical Mapping of 5-Hydroxymethylcytosine in Nanochannel Arrays

73/73 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

1 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 73 checked references that resolve

resolves10.1126/science.1170116

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

resolves10.1126/science.1169786

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

resolves10.1038/nature10008

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

resolves10.1186/gb-2011-12-6-r54

5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells

resolves10.1038/ncomms1240

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

resolves10.1038/nchem.2064

5-Hydroxymethylcytosine is a predominantly stable DNA modification

resolves10.1038/nn.2959

5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

resolves10.1038/srep42790

Regulation of mRNA splicing by MeCP2 via epigenetic modifications in the brain

resolves10.1016/j.cell.2013.02.004

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

resolves10.3389/fgene.2017.00100

New Insights into 5hmC DNA Modification: Generation, Distribution and Function

resolves10.1016/j.celrep.2016.01.008

Epigenomic Co-localization and Co-evolution Reveal a Key Role for 5hmC as a Communication Hub in the Chromatin Network of ESCs

resolves10.15252/embj.201593235

TET‐catalyzed oxidation of intragenic 5‐methylcytosine regulates CTCF‐dependent alternative splicing

resolves10.1016/j.arr.2017.05.002

The role of 5-hydroxymethylcytosine in development, aging and age-related diseases

resolves10.2217/epi-2016-0020

New Hope: The Emerging Role of 5-Hydroxymethylcytosine in Mental Health and Disease

resolves10.1016/j.neurobiolaging.2014.02.002

Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain

resolves10.1093/eep/dvw016

Epigenetic mechanisms involved in the effects of stress exposure: focus on 5-hydroxymethylcytosine: Table 1:

resolves10.1038/onc.2012.67

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

resolves10.4061/2011/870726

Distribution of 5-Hydroxymethylcytosine in Different Human Tissues

resolves10.18632/oncotarget.316

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers

resolves10.1038/nature09586

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

resolves10.1186/s13148-017-0368-9

Single-molecule quantification of 5-hydroxymethylcytosine for diagnosis of blood and colon cancers

resolves10.1182/blood.V122.21.1261.1261

Aberrant 5-Hydroxymethylcytosine Levels Correlate With Poor Overall Survival In Acute Myeloid Leukemia

resolves10.3892/ol.2016.4474

Low level of 5-Hydroxymethylcytosine predicts poor prognosis in non-small cell lung cancer

resolves10.1182/blood-2013-08-518514

Characterization of acute myeloid leukemia based on levels of global hydroxymethylation

resolves10.1038/cr.2017.106

5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages

resolves10.1038/s41422-018-0014-x

Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer

resolves10.1038/cr.2017.121

5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers

resolves10.1126/science.1220671

Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution

resolves10.1016/j.cell.2012.04.027

Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome

resolves10.1093/nar/gkr120

Genomic mapping of 5-hydroxymethylcytosine in the human brain

resolves10.1038/nbt.1732

Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

resolves10.1016/j.molcel.2016.06.028

A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations

resolves10.1038/nbt.3598

Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction

resolves10.1038/nrg3117

Repetitive DNA and next-generation sequencing: computational challenges and solutions

resolves10.1038/nmeth.1779

Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine

resolves10.1038/nmeth.1459

Direct detection of DNA methylation during single-molecule, real-time sequencing

resolves10.1038/nmeth.4189

Mapping DNA methylation with high-throughput nanopore sequencing

resolves10.1038/nmeth.4184

Detecting DNA cytosine methylation using nanopore sequencing

resolves10.1038/nbt.2303

Genome mapping on nanochannel arrays for structural variation analysis and sequence assembly

resolves10.1016/j.copbio.2013.01.009

Beyond sequencing: optical mapping of DNA in the age of nanotechnology and nanoscopy

resolves10.1073/pnas.1600223113

Simultaneous single-molecule epigenetic imaging of DNA methylation and hydroxymethylation

resolves10.1021/ja503677n

Lighting Up Individual DNA Damage Sites by In Vitro Repair Synthesis

resolves10.1039/c3cc42543f

Optical detection of epigenetic marks: sensitive quantification and direct imaging of individual hydroxymethylcytosine bases

resolves10.1093/bioinformatics/btx437

Irys Extract

resolves10.1016/j.exphem.2016.07.009

Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2

resolves10.1093/nar/gkt1080

Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques

resolves10.1038/nbt.2398

Mapping recently identified nucleotide variants in the genome and transcriptome

resolves10.1371/journal.pgen.1002154

Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells

resolves10.1186/gb-2014-15-3-r49

Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain

resolves10.1186/s13072-016-0070-8

Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells

resolves10.18632/oncotarget.15802

Next generation mapping reveals novel large genomic rearrangements in prostate cancer

resolves10.1534/genetics.115.183483

Genome-Wide Structural Variation Detection by Genome Mapping on Nanochannel Arrays

resolves10.1093/bfgp/elp010

The human Major Histocompatibility Complex as a paradigm in genomics research

resolves10.1111/j.1399-0039.2004.00327.x

An update of the HLA genomic region, locus information and disease associations: 2004

resolves10.1016/S0140-6736(02)08158-8

Genetic variations in HLA-B region and hypersensitivity reactions to abacavir

resolves10.1016/j.humimm.2016.04.002

Next-Generation Sequencing of the HLA locus: Methods and impacts on HLA typing, population genetics and disease association studies

resolves10.1038/jhg.2015.102

The impact of next-generation sequencing technologies on HLA research

resolves10.1093/nar/gks865

Histone H2A variants in nucleosomes and chromatin: more or less stable?

resolves10.1016/j.gene.2004.07.036

Functional characterization of a human histone gene cluster duplication

resolves10.1038/nrm2861

Histone variants — ancient wrap artists of the epigenome

resolves10.4161/epi.6.1.13362

DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy

resolves10.1007/s10620-013-2663-4

Analysis of the Genome-Wide DNA Methylation Profile of Side Population Cells in Hepatocellular Carcinoma

resolves10.1038/ni.2284

Genetic variation in Toll-like receptors and disease susceptibility

resolves10.1038/nature22971

Improved maize reference genome with single-molecule technologies

resolves10.1038/nmeth.3454

Assembly and diploid architecture of an individual human genome via single-molecule technologies

resolves10.1002/cbic.201500329

One‐Pot Chemoenzymatic Cascade for Labeling of the Epigenetic Marker 5‐Hydroxymethylcytosine

resolves10.1038/nprot.2011.455

Preparation of megabase-sized DNA from a variety of organisms using the nuclei method for advanced genomics research

resolves10.1093/bioinformatics/btq033

BEDTools: a flexible suite of utilities for comparing genomic features

resolves10.1038/nmeth.1923

Fast gapped-read alignment with Bowtie 2

resolves10.1093/bioinformatics/btp352

The Sequence Alignment/Map format and SAMtools

resolves10.1515/1544-6115.1750

Normalization, bias correction, and peak calling for ChIP-seq

resolves10.1038/nature11247

An integrated encyclopedia of DNA elements in the human genome

resolves10.1093/nar/gkw257

deepTools2: a next generation web server for deep-sequencing data analysis

The 1 reference without a DOI — listed, not checked

no DOI — not checkedref39/cit39

What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-07-23 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

view as graph · paper page

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.1021/acsnano.8b03023"><img src="https://citestamp.com/citestamped/10.1021/acsnano.8b03023/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>

[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.1021/acsnano.8b03023/badge.svg)](https://citestamp.com/citestamped/10.1021/acsnano.8b03023)