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Use of Artificial Intelligence in the Design of Small Peptide Antibiotics Effective against a Broad Spectrum of Highly Antibiotic-Resistant Superbugs
38/38 checkable references clean · checked 2026-08-27
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
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The 38 checked references that resolve
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Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
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Role of membranes in the activities of antimicrobial cationic peptides
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The co-evolution of host cationic antimicrobial peptides and microbial resistance
resolves10.1016/j.chembiol.2006.08.014
Sequence Requirements and an Optimization Strategy for Short Antimicrobial Peptides
resolves10.1038/nbt1113
High-throughput generation of small antibacterial peptides with improved activity
resolves10.1111/j.1747-0285.2007.00543.x
Evaluating Different Descriptors for Model Design of Antimicrobial Peptides with Enhanced Activity Toward <i>P. aeruginosa</i>
resolves10.1016/S0021-9258(19)81553-3
Structure and bactericidal activity of an antibiotic dodecapeptide purified from bovine neutrophils.
resolves10.1128/AAC.43.5.1274
Improved Derivatives of Bactenecin, a Cyclic Dodecameric Antimicrobial Cationic Peptide
resolves10.1038/nprot.2007.203
Use of luminescent bacteria for rapid screening and characterization of short cationic antimicrobial peptides synthesized on cellulose using peptide array technology
resolves10.1038/nprot.2007.160
Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for synthesis of large numbers of peptides in a parallel and addressable fashion
resolves10.2174/1386207053764558
Design of Host Defence Peptides for Antimicrobial and Immunity Enhancing Activities
resolves10.1016/j.peptides.2004.09.020
Protegrin structure–activity relationships: using homology models of synthetic sequences to determine structural characteristics important for activity
resolves10.1002/psc.295
Antibiotic activity of pentadecapeptides modelled from amino acid descriptors
resolves10.1002/psc.604
Modelling of anti‐HSV activity of lactoferricin analogues using amino acid descriptors
resolves10.1016/j.bmc.2006.05.005
QSAR analysis of antimicrobial and haemolytic effects of cyclic cationic antimicrobial peptides derived from protegrin-1
resolves10.1021/ci034147w
Inductive Electronegativity Scale. Iterative Calculation of Inductive Partial Charges
resolves10.3390/i6010063
Inductive QSAR Descriptors. Distinguishing Compounds with Antibacterial Activity by Artificial Neural Networks
resolves10.1021/ci0601517
Comparative QSAR- and Fragments Distribution Analysis of Drugs, Druglikes, Metabolic Substances, and Antimicrobial Compounds
resolves10.1021/ci050480j
Can ‘Bacterial-Metabolite-Likeness' Model Improve Odds of ‘in Silico' Antibiotic Discovery?
resolves10.1038/nature736
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
resolves10.4049/jimmunol.177.11.8154
The Role of TLR2 In Vivo following Challenge with
<i>Staphylococcus aureus</i>
and Prototypic Ligands
resolves10.1038/nbt1288
An anti-infective peptide that selectively modulates the innate immune response
resolves10.1128/AAC.47.8.2507-2512.2003
In Vivo Antibacterial Activity of S-3578, a New Broad-Spectrum Cephalosporin: Methicillin-Resistant
<i>Staphylococcus aureus</i>
and
<i>Pseudomonas aeruginosa</i>
Experimental Infection Models
resolves10.1021/jm8015365
Identification of Novel Antibacterial Peptides by Chemoinformatics and Machine Learning
resolves10.1128/AAC.35.1.73
Reevaluation of the factors involved in the efficacy of new beta-lactams against Enterobacter cloacae
resolves10.1128/JB.187.14.4908-4920.2005
A Cystic Fibrosis Epidemic Strain of
<i>Pseudomonas aeruginosa</i>
Displays Enhanced Virulence and Antimicrobial Resistance
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