Reference health
Synthesis and Biological Evaluation of Heterocyclic Ring-Fused Betulinic Acid Derivatives as Novel Inhibitors of Osteoclast Differentiation and Bone Resorption
56/56 checkable references clean · checked 2026-07-22
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 56 checked references that resolve
resolves10.1056/NEJMra053077
Bone Quality — The Material and Structural Basis of Bone Strength and Fragility
resolves10.1172/JCI4561
Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1.
resolves10.1210/endo.139.6.6087
Editorial: Cytokines, Estrogen, and Postmenopausal Osteoporosis—The Second Decade
resolves10.1517/14712590902845610
RANKL inhibition: Clinical implications for the management of patients with multiple myeloma and solid tumors with bone metastases
resolves10.1097/01.bor.0000127824.42507.68
Bone loss in inflammatory arthritis: mechanisms and treatment strategies
resolves10.1186/ar1857
resolves10.1007/s774-002-8446-8
Comparison of the effects of transdermal estrogen, oral estrogen, and oral estrogen-progestogen therapy on bone mineral density in postmenopausal women
resolves10.1111/j.1745-7599.2007.00269.x
Benefits of hormone replacement therapy in postmenopausal women
resolves10.1080/13697130902721873
Estrogens as first-choice therapy for osteoporosis prevention and treatment in women under 60
resolves10.1016/0091-7435(88)90064-3
Benefits and risks of menopausal estrogen and/or progestin hormone use
resolves10.4037/ajcc2005.14.2.157
Estrogen Plus Progestin, Benefits and Risks: The “Women’s Health Initiative” Trials
resolves10.1080/13697130903006837
Hormone therapy and risk of venous thromboembolism among postmenopausal women
resolves10.1007/s00198-007-0540-8
Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
resolves10.1634/theoncologist.9-90004-28
Safety of Intravenous and Oral Bisphosphonates and Compliance With Dosing Regimens
resolves10.1634/theoncologist.10-5-318
In Response to Body Letter to the Editor Regarding “Safety of Intravenous and Oral Bisphosphonates and Compliance with Dosing Regimens”
resolves10.1007/s00432-010-0907-7
Bisphosphonate-induced osteonecrosis of the jaw: a review of 2,400 patient cases
resolves10.1016/8756-3282(94)00033-V
The anabolic effects of parathyroid hormone on cortical bone mass, dimensions and strength—assessed in a sexually mature, ovariectomized rat model
resolves10.1210/endo.136.8.7628403
Evidence that intermittent treatment with parathyroid hormone increases bone formation in adult rats by activation of bone lining cells.
resolves10.1039/a902202c
The influence of natural products upon drug discovery (Antiquity to late 1999)
resolves10.4049/jimmunol.176.5.3127
Acetyl-11-Keto-β-Boswellic Acid Potentiates Apoptosis, Inhibits Invasion, and Abolishes Osteoclastogenesis by Suppressing NF-κB and NF-κB-Regulated Gene Expression
resolves10.1016/j.chembiol.2007.06.010
A Triterpene Glycoside from Black Cohosh that Inhibits Osteoclastogenesis by Modulating RANKL and TNFα Signaling Pathways
resolves10.1016/j.carres.2009.01.019
Glycoside modification of oleanolic acid derivatives as a novel class of anti-osteoclast formation agents
resolves10.1016/j.ejmech.2008.12.024
Synthesis and evaluation of a novel series of heterocyclic oleanolic acid derivatives with anti-osteoclast formation activity
resolves10.1002/jbmr.242
Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways
resolves10.1248/bpb.28.1879
Increase in Bone Mass and Bone Strength by Sambucus williamsii HANCE in Ovariectomized Rats
resolves10.1055/s-2006-957705
Studies on the Anti-Inflammatory Activity of Rhizomes of<i>Nelumbo nucifera</i>
resolves10.1021/jm950922q
Betulinic Acid and Dihydrobetulinic Acid Derivatives as Potent Anti-HIV Agents
resolves10.1097/CAD.0b013e3283357c62
Betulinic acid, a natural compound with potent anticancer effects
resolves10.1124/jpet.107.123356
Reciprocal Regulation of Endothelial Nitric-Oxide Synthase and NADPH Oxidase by Betulinic Acid in Human Endothelial Cells
resolves10.1021/jf904158k
Betulinic Acid Stimulates the Differentiation and Mineralization of Osteoblastic MC3T3-E1 Cells: Involvement of BMP/Runx2 and β-Catenin Signals
resolves10.1016/j.bmcl.2009.10.017
Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B
resolves10.1016/0960-894X(96)00173-4
Inhibitory effects of scopadulcic acid B and its derivatives on bone resorption and osteoclast formation in vitro
resolves10.1242/dev.122.10.3151
Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis
resolves10.1006/excr.2002.5612
Osteoclasts from Mice Deficient in Tartrate-Resistant Acid Phosphatase Have Altered Ruffled Borders and Disturbed Intracellular Vesicular Transport
resolves10.1359/JBMR.040603
Intracellular Machinery for Matrix Degradation in Bone-Resorbing Osteoclasts
resolves10.1359/jbmr.1999.14.11.1934
Expression Profiles of mRNAs for Osteoblast and Osteoclast Proteins as Indicators of Bone Loss in Mouse Immobilization Osteopenia Model
resolves10.1016/S0039-128X(00)00097-0
Regulation of collagenolytic cysteine protease synthesis by estrogen in osteoclasts
The 2 references without a DOI — listed, not checked
no DOI — not checkedCCDC 853840 contains the supplementary crystallographic data of compound20for this paper. These data can be obtained free of charge viahttp://www.ccdc.cam.ac.uk/cgi-bin/catreq.cgior by emailingdata-request@ccdc.cam.ac.ukor by contacting The Cambridge Crystallographic Data Centre, 12, Union Road, Cambridge CB2 1EZ, U.K. (fax, +44 1223 336 33).
no DOI — not checkedref33/cit33
What this badge says. CiteStamped means the CHECKABLE references of this
work were clean at the dated check: each resolved to a known work in a public registry, and none
carried a retraction notice at that time. It says nothing about the quality, findings,
or importance of the work itself, and nothing about references deposited without a DOI.
checked 2026-07-22 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record
Embed this badge
Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.
<a href="https://citestamp.com/citestamped/10.1021/jm201540h"><img src="https://citestamp.com/citestamped/10.1021/jm201540h/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[](https://citestamp.com/citestamped/10.1021/jm201540h)