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2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) Is Enantioselectively Oxidized to Hydroxylated Metabolites by Rat Liver Microsomes
37/37 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
5 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 37 checked references that resolve
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Neurochemical Targets and Behavioral Effects of Organohalogen Compounds: An Update
resolves10.1021/tx050196m
Structure−Activity Relationship for Noncoplanar Polychlorinated Biphenyl Congeners toward the Ryanodine Receptor-Ca<sup>2+</sup>Channel Complex Type 1 (RyR1)
resolves10.1016/S0045-6535(97)00229-4
Theoretical considerations about chiral PCBs and their methylthio and methylsulfonyl metabolites being possibly present as stable enantiomers
resolves10.1016/j.aquatox.2006.02.033
Biotransformation of polychlorinated biphenyls (PCBs) and bioformation of hydroxylated PCBs in fish
resolves10.1016/j.chemosphere.2008.10.038
Hydroxylated polychlorinated biphenyls (OH-PCBs) in the blood of mammals and birds from Japan: Lower chlorinated OH-PCBs and profiles
resolves10.1021/es1003928
Polychlorinated Biphenyls and Their Hydroxylated Metabolites (OH-PCBs) in the Blood of Toothed and Baleen Whales Stranded along Japanese Coastal Waters
resolves10.1289/ehp.5946
Human prenatal and postnatal exposure to polybrominated diphenyl ethers, polychlorinated biphenyls, polychlorobiphenylols, and pentachlorophenol.
resolves10.1016/j.chemosphere.2010.12.050
Changes in serum concentrations of polychlorinated biphenyls (PCBs), hydroxylated PCB metabolites and pentachlorophenol during pregnancy
resolves10.1021/es902149b
Distribution of PCBs, Their Hydroxylated Metabolites, and Other Phenolic Contaminants in Human Serum from Two European Countries
resolves10.1074/jbc.272.24.15145
ortho-Substituted Polychlorinated Biphenyls Alter Microsomal Calcium Transport by Direct Interaction with Ryanodine Receptors of Mammalian Brain
resolves10.1016/S0026-895X(25)08790-5
Ortho-substituted polychlorinated biphenyls alter calcium regulation by a ryanodine receptor-mediated mechanism: structural specificity toward skeletal- and cardiac-type microsomal calcium release channels.
resolves10.1021/es902208u
Chiral Polychlorinated Biphenyl Transport, Metabolism, and Distribution: A Review
resolves10.1021/tx800328u
Enantiomeric Specificity of (−)-2,2′,3,3′,6,6′-Hexachlorobiphenyl toward Ryanodine Receptor Types 1 and 2
resolves10.1021/es802237u
Chiral Polychlorinated Biphenyls Are Biotransformed Enantioselectively by Mammalian Cytochrome P-450 Isozymes to Form Hydroxylated Metabolites
resolves10.1016/j.chroma.2008.08.044
Gas chromatographic separation of methoxylated polychlorinated biphenyl atropisomers
resolves10.1021/es061584t
Enantioselective Formation of Methyl Sulfone Metabolites of 2,2‘,3,3‘,4,6‘-Hexachlorobiphenyl in Rat
resolves10.1021/tx800059j
2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) Atropisomers Interact Enantioselectively with Hepatic Microsomal Cytochrome P450 Enzymes
resolves10.1021/tx990030j
2,2‘,3,3‘,6,6‘-Hexachlorobiphenyl Hydroxylation by Active Site Mutants of Cytochrome P450 2B1 and 2B11
resolves10.1016/0003-2697(78)90714-5
A simple method for detecting steroid aggregation and estimating solubility in aqueous solutions
resolves10.1016/S0021-9258(18)32664-4
Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics.
resolves10.1002/etc.5620190319
Bioaccumulation patterns of polychlorinated biphenyls and chlorinated pesticides in Northwest Atlantic pilot whales
resolves10.1023/A:1006835712436
A Microassay for the detection of low levels of cytochrome P450 O-deethylation activities with alkoxyresorufin substrates
resolves10.1080/00498250110074063
Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes
resolves10.1016/0006-2952(83)90209-5
Metabolism of 2,2′,3,3′,6,6′-hexachlorobiphenyl and 2,2′,4,4′,5,5′-hexachlorobiphenyl by human hepatic microsomes
resolves10.1021/es047987f
Congener-Specific Tissue Distribution of Aroclor 1254 and a Highly Chlorinated Environmental PCB Mixture in Rats
resolves10.1016/j.chroma.2008.10.089
Simultaneous extraction and clean-up of polychlorinated biphenyls and their metabolites from small tissue samples using pressurized liquid extraction
resolves10.1016/S0021-9258(20)82065-1
Non-arene oxide aromatic ring hydroxylation of 2,2',5,5'-tetrachlorobiphenyl as the major metabolic pathway catalyzed by phenobarbital-induced rat liver microsomes.
resolves10.1002/jhrc.1240190703
Determination of the gas chromatographic elution sequences of the (+)‐ and (−)‐enantiomers of stable atropisomeric PCBs on Chirasil‐dex
resolves10.1021/es901781p
Clearance of Polychlorinated Biphenyl Atropisomers is Enantioselective in Female C57Bl/6 Mice
resolves10.1002/chir.20342
Enantioselective disposition of PCB 136 (2,2′,3,3′,6,6′‐hexachlorobiphenyl) in C57BL/6 mice after oral and intraperitoneal administration
The 5 references without a DOI — listed, not checked
no DOI — not checkedPCBs: Recent Advances in Environmental Toxicology and Health Effects
no DOI — not checkedToxicological Profile for Polychlorinated Biphenyls (PCBs)
no DOI — not checkedThe Handbook of Environmental Chemistry: New Types of Persistent Halogenated Compounds
no DOI — not checkedref18/cit18
no DOI — not checkedref43/cit43
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