Reference health
The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor
169/169 checkable references clean · checked 2026-09-10
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
24 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 169 checked references that resolve
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Functional role of AhR in the expression of toxic effects by TCDD
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Mechanisms of Ligand-Induced Aryl Hydrocarbon Receptor-Mediated Biochemical and Toxic Responses
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Role of the Ah Receptor and the Dioxin‐Inducible [<i>Ah</i>] Gene Battery in Toxicity, Cancer, and Signal Transductiona
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Substrate-Induced Synthesis And Other Properties Of Benzpyrene Hydroxylase In Rat Liver
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Xenobiotic-Metabolizing Enzymes Involved in Activation and Detoxification of Carcinogenic Polycyclic Aromatic Hydrocarbons
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Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse
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Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.
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3,4,3′,4′-Tetrachloro Azoxybenzene and Azobenzene: Potent Inducers of Aryl Hydrocarbon Hydroxylase
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Association of the Ah receptor with the 90-kDa heat shock protein.
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The specific DNA binding activity of the dioxin receptor is modulated by the 90 kd heat shock protein.
resolves10.1074/jbc.272.17.11452
Ligand-dependent Interaction of the Aryl Hydrocarbon Receptor with a Novel Immunophilin Homolog in Vivo
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Hepatitis B Virus X-Associated Protein 2 Is a Subunit of the Unliganded Aryl Hydrocarbon Receptor Core Complex and Exhibits Transcriptional Enhancer Activity
resolves10.1074/jbc.272.14.8878
A Novel Cytoplasmic Protein That Interacts with the Ah Receptor, Contains Tetratricopeptide Repeat Motifs, and Augments the Transcriptional Response to 2,3,7,8-Tetrachlorodibenzo-p-dioxin
resolves10.1074/jbc.274.19.13519
Evidence That the Co-chaperone p23 Regulates Ligand Responsiveness of the Dioxin (Aryl Hydrocarbon) Receptor
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Identification of Functional Domains of the Aryl Hydrocarbon Receptor
resolves10.1073/pnas.89.17.8185
Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor.
resolves10.1016/S0959-437X(99)00003-9
Remembrance of things PAS: regulation of development by bHLH–PAS proteins
resolves10.1073/pnas.90.18.8566
In vitro analysis of Ah receptor domains involved in ligand-activated DNA recognition.
resolves10.1074/jbc.273.5.2895
Nuclear Localization and Export Signals of the Human Aryl Hydrocarbon Receptor
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The hsp90 Co-chaperone XAP2 Alters Importin β Recognition of the Bipartite Nuclear Localization Signal of the Ah Receptor and Represses Transcriptional Activity
resolves10.1126/science.256.5060.1193
Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor
resolves10.1016/0092-8674(82)90427-5
The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA
resolves10.1016/S0021-9258(19)50499-9
Protein-DNA interactions at a dioxin-responsive enhancer. Mutational analysis of the DNA-binding site for the liganded Ah receptor.
resolves10.1016/S0021-9258(18)53289-0
Protein-DNA interactions at a dioxin-responsive enhancer. Analysis of six bona fide DNA-binding sites for the liganded Ah receptor.
resolves10.1016/j.abb.2004.09.031
Role of coactivators in transcriptional activation by the aryl hydrocarbon receptor
resolves10.1093/oxfordjournals.jbchem.a022633
Nucleocytoplasmic Shuttling of the Aryl Hydrocarbon Receptor
resolves10.1074/jbc.274.51.36351
Degradation of the Basic Helix-Loop-Helix/Per-ARNT-Sim Homology Domain Dioxin Receptor Via the Ubiquitin/Proteasome Pathway
resolves10.1074/jbc.274.40.28708
Aryl Hydrocarbon Receptor Imported into the Nucleus following Ligand Binding Is Rapidly Degraded via the Cytosplasmic Proteasome following Nuclear Export
resolves10.1074/jbc.275.12.8432
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced Degradation of Aryl Hydrocarbon Receptor (AhR) by the Ubiquitin-Proteasome Pathway
resolves10.1101/gad.13.1.20
Identification of a novel mechanism of regulation of Ah (dioxin) receptor function
resolves10.1007/s00239-005-0134-z
A Revised Evolutionary History of the CYP1A Subfamily: Gene Duplication, Gene Conversion, and Positive Selection
resolves10.1021/bi062320m
Ensemble Modeling of Substrate Binding to Cytochromes P450: Analysis of Catalytic Differences between CYP1A Orthologs<sup>,</sup>
resolves10.1242/dev.126.17.3937
The Spineless-Aristapedia and Tango bHLH-PAS proteins interact to control antennal and tarsal development in <i>Drosophila</i>
resolves10.1101/gad.12.9.1290
Control of distal antennal identity and tarsal development in Drosophila by spineless-aristapedia, a homolog of the mammalian dioxin receptor
resolves10.1038/nature04615
Stochastic spineless expression creates the retinal mosaic for colour vision
resolves10.1073/pnas.95.6.2844
<i>Caenorhabditis elegans</i>
orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator
resolves10.1016/j.ydbio.2004.02.004
The Caenorhabditis elegans aryl hydrocarbon receptor, AHR-1, regulates neuronal development
resolves10.1016/S0378-1119(01)00724-7
An aryl hydrocarbon receptor (AHR) homologue from the soft-shell clam, Mya arenaria: evidence that invertebrate AHR homologues lack 2,3,7,8-tetrachlorodibenzo-p-dioxin and β-naphthoflavone binding
resolves10.1006/bbrc.1998.9519
Markedly Increased Constitutive CYP1A1 mRNA Levels in the Fertilized Ovum of the Mouse
resolves10.1002/jez.a.323
Unexpected diversity of aryl hydrocarbon receptors in non‐mammalian vertebrates: insights from comparative genomics
resolves10.1126/science.7732381
Immune System Impairment and Hepatic Fibrosis in Mice Lacking the Dioxin-Binding Ah Receptor
resolves10.1073/pnas.93.13.6731
Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.
resolves10.1073/pnas.190256997
Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice
resolves10.1074/jbc.M403690200
A Maternal Ahr Null Genotype Sensitizes Embryos to Chemical Teratogenesis
resolves10.1073/pnas.0404379101
Gestational exposure of
<i>Ahr</i>
and
<i>Arnt</i>
hypomorphs to dioxin rescues vascular development
resolves10.1074/jbc.M412899200
The Murine Cyp1a1 Gene Is Expressed in a Restricted Spatial and Temporal Pattern during Embryonic Development
resolves10.1016/S0003-9861(03)00174-7
Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues
resolves10.1146/annurev.pharmtox.43.100901.135828
Activation of the Aryl Hydrocarbon Receptor by Structurally Diverse Exogenous and Endogenous Chemicals
resolves10.1074/jbc.272.50.31755
Signal Transduction-mediated Activation of the Aryl Hydrocarbon Receptor in Rat Hepatoma H4IIE Cells
resolves10.1016/0009-2797(81)90046-6
Structure-activity relationships in halogenated biphenyls: Unifying hypothesis for structural specificity
resolves10.1021/tx00048a005
Three-Dimensional Quantitative Structure-Activity Relationships of Dioxins and Dioxin-like Compounds: Model Validation and Ah Receptor Characterization
resolves10.1002/qsar.19870060102
Polychlorinated Dibenzofuran (PCDF) Binding to the Ah Receptor(s) and Associated Enzyme Induction. Theoretical Model Based on Molecular Parameters
resolves10.1021/tx0300380
Structure−Activity Relationships for the Toxicity of Polychlorinated Dibenzofurans: Approach through Density Functional Theory-Based Descriptors
resolves10.1016/j.chemosphere.2006.01.010
3D QSAR studies of dioxins and dioxin-like compounds using CoMFA and CoMSIA
resolves10.1146/annurev.pa.22.040182.002505
2,3,7,8-Tetrachlorodibenzo-<i>p</i>-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity
resolves10.1038/220702a0
Chemical and Toxicological Evaluations of Isolated and Synthetic Chloro Derivatives of Dibenzo-p-dioxin
resolves10.1016/0041-008X(74)90060-X
Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C57B16 mice
resolves10.1016/0041-008X(78)90195-3
The comparative toxicity of chlorinated dibenzo-p-dioxins in mice and guinea pigs
resolves10.1046/j.1365-2443.1997.1490345.x
Loss of teratogenic response to 2,3,7,8‐tetrachlorodibenzo‐
<i>p</i>
‐dioxin (TCDD) in mice lacking the Ah (dioxin) receptor
resolves10.1006/taap.1996.0210
Aryl-hydrocarbon Receptor-Deficient Mice Are Resistant to 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Toxicity
resolves10.1093/toxsci/47.1.86
Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice
resolves10.1007/BF00316581
Teratological studies on the TCDD congener 3,3?,4,4?-tetrachloroazoxybenzene in sensitive and nonsensitive mouse strains: Evidence for direct effect on embryonic tissues
resolves10.1016/0041-008X(83)90288-0
Immunosuppressive effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in strains of mice with different susceptibility to induction of aryl hydrocarbon hydroxylase
resolves10.1016/0041-008X(85)90314-X
Dose-related effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C57BL6J and DBA2J mice
resolves10.1016/0272-0590(90)90257-K
Role of the Ah locus in suppression of cytotoxic T lymphocyte activity by halogenated aromatic hydrocarbons (PCBs and TCDD): Structure-activity relationships and effects in C57Bl/6 mice congenic at the Ah locus
resolves10.1016/0300-483X(85)90108-8
Polychlorinated dibenzofurans (PCDFs): Correlation between in vivo and in vitro structure-activity relationships
resolves10.1289/ehp.8981225
Environmental occurrence, abundance, and potential toxicity of polychlorinated biphenyl congeners: considerations for a congener-specific analysis.
resolves10.1289/ehp.93100259
Toxicology, structure-function relationship, and human and environmental health impacts of polychlorinated biphenyls: progress and problems.
resolves10.1016/0165-1110(89)90007-9
Polychlorinated biphenyls (PCBs): mutagenicity and carcinogenicity
resolves10.1016/0009-2797(82)90045-X
Binding of polychlorinated biphenyls classified as either phenobarbitone-, 3-methylcholanthrene- or mixed-type inducers to cytosolic Ah receptor
resolves10.3109/10408449009089873
Polychlorinated Biphenyls (PCBs), Dibenzo-p-Dioxins (PCDDs), Dibenzofurans (PCDFs), and Related Compounds: Environmental and Mechanistic Considerations Which Support the Development of Toxic Equivalency Factors (TEFs)
resolves10.1016/0378-4274(82)90142-4
PCB isomers and congeners: Induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase enzyme activities in rat hepatoma cells
resolves10.1016/j.marenvres.2004.03.001
Relative potency of PAHs and heterocycles as aryl hydrocarbon receptor agonists in fish
resolves10.1074/jbc.C100238200
Indirubin and Indigo Are Potent Aryl Hydrocarbon Receptor Ligands Present in Human Urine
resolves10.1016/j.abb.2004.01.002
Aryl hydrocarbon receptor response to indigoids in vitro and in vivo
resolves10.1016/j.bcp.2003.08.019
Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin
resolves10.1016/j.bbrc.2004.04.066
Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo
resolves10.1016/j.abb.2006.02.008
A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo
resolves10.1016/j.jsbmb.2005.07.003
Induction of cytochrome P450-1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand
resolves10.1016/S0021-9258(18)46990-6
Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors.
resolves10.1016/S0006-2952(97)00417-6
Sustained Increase in Intracellular Free Calcium and Activation of Cyclooxygenase-2 Expression in Mouse Hepatoma Cells Treated with Dioxin
resolves10.1021/bp960067j
Possible Role of Arachidonic Acid in Stress‐Induced Cytochrome P450IA1 Activity<sup>1</sup>
resolves10.1124/mol.52.4.590
Aryl Hydrocarbon Receptor-Dependent Induction of Cyp1a1 by Bilirubin in Mouse Hepatoma Hepa 1c1c7 Cells
resolves10.1006/abbi.1998.0814
Activation of the Ah Receptor Signal Transduction Pathway by Bilirubin and Biliverdin
resolves10.1016/0006-8993(89)91539-4
Tryptamine receptors: neurochemical and electrophysiological evidence for postsynaptic and functional binding sites
resolves10.1016/S0021-9258(18)47743-5
Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances.
resolves10.1016/1074-5521(95)90090-X
Structure elucidation of two tryptophan-derived, high affinity Ah receptor ligands
resolves10.1016/j.cbi.2004.08.005
Metabolic fate of the Ah receptor ligand 6-formylindolo[3,2-b]carbazole
resolves10.1016/S0009-2797(97)00111-7
Rapid and transient induction of CYP1A1 gene expression in human cells by the tryptophan photoproduct 6-formylindolo[3,2-b]carbazole
resolves10.1006/abbi.2000.2037
Regulation of CYP1A1 Transcription via the Metabolism of the Tryptophan-Derived 6-Formylindolo[3,2-b]carbazole
resolves10.1093/toxsci/kfi154
Identification of the Tryptophan Photoproduct 6-Formylindolo[3,2-b]carbazole, in Cell Culture Medium, as a Factor That Controls the Background Aryl Hydrocarbon Receptor Activity
resolves10.1046/j.1523-1747.2000.00876.x
Ultraviolet-B Exposure of Human Skin Induces Cytochromes P450 1A1 and 1B1
resolves10.1007/BF01963137
Influence of chronic UV-light exposure on hepatic and cutaneous monooxygenases
resolves10.1111/1523-1747.ep12524446
Additive Effects of Ultraviolet B and Crude Coal Tar on Cutaneous Carcinogen Metabolism: Possible Relevance to the Tumorigenicity of the Goeckerman Regimen
resolves10.1007/s004030050151
Influence of UVA and UVB irradiation on hepatic and cutaneous P450 isoenzymes
resolves10.1093/toxsci/kfj065
Sunlight Generates Multiple Tryptophan Photoproducts Eliciting High Efficacy CYP1A Induction in Chick Hepatocytes and In Vivo
resolves10.1021/jf030252u
Activation of the Ah Receptor by Extracts of Dietary Herbal Supplements, Vegetables, and Fruits
resolves10.4161/cc.4.9.1993
Molecular Targets and Anticancer Potential of Indole-3-Carbinol and Its Derivatives
resolves10.1093/carcin/bgi270
3,3′-Diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5
resolves10.1080/15287398709531021
Structure—activity relationships of dietary indoles: A proposed mechanism of action as modifiers of xenobiotic metabolism
resolves10.1073/pnas.88.21.9543
Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
resolves10.1074/jbc.270.38.22548
Regulation of CYP1A1 by Indolo[3,2-b]carbazole in Murine Hepatoma Cells
resolves10.1016/S0006-2952(99)00165-3
Cytostatic and antiestrogenic effects of 2-(indol-3-ylmethyl)-3,3′-diindolylmethane, a major in vivo product of dietary indole-3-carbinol
resolves10.1093/carcin/19.9.1631
Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
resolves10.1016/0006-2952(93)90258-X
Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation
resolves10.1146/annurev.nutr.22.111401.144957
D
<scp>IETARY</scp>
F
<scp>LAVONOIDS</scp>
: Bioavailability, Metabolic Effects, and Safety
resolves10.1159/000399407
The Flavonoids. A Class of Semi-Essential Food Components: Their Role in Human Nutrition
resolves10.1248/bpb.26.532
Activation of the Aryl Hydrocarbon Receptor by Some Vegetable Constituents Determined Using in Vitro Reporter Gene Assay.
resolves10.1289/ehp.6322
Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context.
resolves10.1042/bj3400715
Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially
resolves10.1172/JCI106966
Studies on the pathogenesis of the pseudohermaphroditism in the mouse with testicular feminization
resolves10.1016/0092-8674(74)90040-3
Characterization of a hormone receptor defect in the androgen-insensitivity mutant
resolves10.1016/S0021-9258(17)33974-1
Cytochrome P450IA1 is rapidly induced in normal human keratinocytes in the absence of xenobiotics.
resolves10.1016/S0021-9258(18)31723-X
Suspension-mediated induction of Hepa 1c1c7 Cyp1a-1 expression is dependent on the Ah receptor signal transduction pathway.
resolves10.1006/abbi.2001.2475
Transient Expression of CYP1A1 in Rat Epithelial Cells Cultured in Suspension
resolves10.1016/j.taap.2003.12.025
Disruption of cell?cell contact maximally but transiently activates AhR-mediated transcription in 10T1/2 fibroblasts*1
resolves10.1074/jbc.M310492200
Cell Density Regulates Intracellular Localization of Aryl Hydrocarbon Receptor
resolves10.1128/MCB.16.5.2144
The Aromatic Hydrocarbon Receptor Modulates the Hepa 1c1c7 Cell Cycle and Differentiated State Independently of Dioxin
resolves10.1073/pnas.0503488102
Aryl hydrocarbon receptor activation by cAMP vs. dioxin: Divergent signaling pathways
resolves10.1073/pnas.0607296104
The Aryl hydrocarbon receptor is activated by modified low-density lipoprotein
resolves10.1021/bp00036a009
Induction of Cytochrome P‐4501A1 Activity in Response to Sublethal Stresses in Microcarrier‐Attached Hep G2 Cells
resolves10.1080/10623320490432434
Endothelial Cell Cytochrome P450 1A1 and 1B1: Up-Regulation by Shear Stress
resolves10.1006/bbrc.1995.1316
Possible Involvement of the AH Receptor in the Induction of Cytochrome P-450IA1 Under Conditions of Hydrodynamic Shear in Microcarrier-Attached Hepatoma Cell Lines
resolves10.1016/0016-5085(90)90963-2
Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450
resolves10.1006/bbrc.1994.2098
Thiabendazole Is an Inducer of Cytochrome P4501A1 in Cultured Rabbit Hepatocytes
resolves10.1211/002235703765951375
The effects of mebendazole on P4501A activity in rat hepatocytes and HepG2 cells. Comparison with tiabendazole and omeprazole
resolves10.1007/s00228-002-0512-z
Cytochrome P 450 1A1/2 induction by antiparasitic drugs: dose-dependent increase in ethoxyresorufin O-deethylase activity and mRNA caused by quinine, primaquine and albendazole in HepG2 cells
resolves10.1016/0006-2952(91)90119-P
Inducing effect of oxfendazole on cytochrome P450IA2 in rabbit liver
resolves10.1006/abbi.1996.0451
Differences in Inducibility of CYP1A1-mRNA by Benzimidazole Compounds between Human and Mouse Cells: Evidences of a Human-Specific Signal Transduction Pathway forCYP1A1Induction
resolves10.1177/096032719901800206
Species differences in hepatocyte induction of CYP1A1 and CYP1A2 by omeprazole
resolves10.1016/0006-291X(92)91130-I
Omeprazole, an inducer of human CYP1A1 and 1A2, is not a ligand for the Ah receptor
resolves10.1016/j.lfs.2003.09.056
The role of protein tyrosine kinases in CYP1A1 induction by omeprazole and thiabendazole in rat hepatocytes
resolves10.1006/abbi.1998.0869
Induction of Cytochrome P-450 1A1 by Omeprazole in Human HepG2 Cells Is Protein Tyrosine Kinase-Dependent and Is Not Inhibited by α-Naphthoflavone
resolves10.1074/jbc.M305880200
Suppression by p38 MAP Kinase Inhibitors (Pyridinyl Imidazole Compounds) of Ah Receptor Target Gene Activation by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and the Possible Mechanism
resolves10.1016/S0006-2952(98)00304-9
Cytochrome 1A1 induction by primaquine in human hepatocytes and HepG2 cells: absence of binding to the aryl hydrocarbon receptor
resolves10.1016/S0022-3565(24)29529-X
Transcriptional and Post-Translational Regulation of CYP1A1 by Primaquine
resolves10.1016/S0006-2952(98)00143-9
Effect of Curcumin on the Aryl Hydrocarbon Receptor and Cytochrome P450 1A1 in MCF-7 Human Breast Carcinoma Cells
resolves10.1177/026119290403200408
Cytotoxicity of the Dicarboximide Fungicides, Vinclozolin and Iprodione, in Rat Hepatoma-derived Fa32 cells
resolves10.1016/0006-2952(94)90594-0
Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by ergosterol biosynthesis inhibiting fungicides (EBIFs)
resolves10.1016/j.toxlet.2005.04.010
Vinclozolin, a widely used fungizide, enhanced BaP-induced micronucleus formation in human derived hepatoma cells by increasing CYP1A1 expression
resolves10.1124/mol.65.2.416
Different Structural Requirements of the Ligand Binding Domain of the Aryl Hydrocarbon Receptor for High- and Low-Affinity Ligand Binding and Receptor Activation
resolves10.1006/taap.1997.8120
Carbaryl InducesCYP1A1Gene Expression in HepG2 and HaCaT Cells but Is Not a Ligand of the Human Hepatic Ah Receptor
resolves10.1006/taap.1998.9999
Carbaryl, a Carbamate Insecticide, Is a Ligand for the Hepatic Ah (Dioxin) Receptor
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