Reference health
Congenital leptin deficiency is associated with severe early-onset obesity in humans
19/19 checkable references clean · checked 2026-08-25
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 19 checked references that resolve
resolves10.1073/pnas.92.15.6957
Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus.
resolves10.1038/377530a0
The role of neuropeptide Y in the antiobesity action of the obese gene product
resolves10.1038/ng0996-95
Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice
resolves10.1126/science.7624776
Effects of the
<i>obese</i>
Gene Product on Body Weight Regulation in
<i>ob</i>
/
<i>ob</i>
Mice
resolves10.1126/science.7624777
Weight-Reducing Effects of the Plasma Protein Encoded by the
<i>obese</i>
Gene
resolves10.1126/science.7624778
Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks
resolves10.1073/pnas.93.25.14795
Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy
resolves10.2337/diab.45.5.679
Absence of Mutations in the Human <i>OB</i> Gene in Obese/Diabetic Subjects
resolves10.1172/JCI118007
Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity.
resolves10.1007/s001250050610
The causes of obesity: advances in molecular biology but stagnation on the genetic front
resolves10.1038/nm1195-1155
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
resolves10.1007/BF00210743
The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences
resolves10.1038/nm0297-238
Relatively low plasma leptin concentrations precede weight gain in Pima Indians
resolves10.1126/science.275.5296.88
Early Onset of Reproductive Function in Normal Female Mice Treated with Leptin
The 2 references without a DOI — listed, not checked
no DOI — not checkedYork, D. A., Otto, W. & Taylor, T. G. Thyroid status of obese (ob/ob) mice and its relationship to adipose tissue metabolism. Comp. Biochem. Physiol. 590, 59–65 (1978).
no DOI — not checkedGarrow, J. S. & Webster, J. Quetelet's Index (W/H2) as a measure of fatness. Int. J. Obes. 9, 147–153 (1985).
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