Reference health

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

https://doi.org/10.1038/561
CiteStamped reference-health badge
23/23 checkable references clean · checked 2026-08-12

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

7 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 23 checked references that resolve
resolves10.1016/0092-8674(86)90263-1
DNA methylation affects the formation of active chromatin
resolves10.1016/S0168-9525(97)01181-5
Cytosine methylation and the ecology of intragenomic parasites
resolves10.1016/S0168-9525(00)89009-5
Gene number, noise reduction and biological complexity
resolves10.1038/366362a0
Role for DNA methylation in genomic imprinting
resolves10.1093/carcin/18.5.869
Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis
resolves10.1073/pnas.94.6.2103
Altered DNA methylation and genome instability: A new pathway to cancer?
resolves10.1016/S0065-230X(08)60702-2
Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia
resolves10.1073/pnas.84.5.1177
Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene.
resolves10.1016/S0960-9822(97)70086-1
DNA methylation directs a time-dependent repression of transcription initiation
resolves10.1016/S0092-8674(00)81887-5
MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic Chromatin
resolves10.1128/MCB.16.1.414
DNA Methylation Specifies Chromosomal Localization of MeCP2
resolves10.1016/0092-8674(95)90355-0
Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3
resolves10.1016/S0092-8674(00)80215-9
Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression
resolves10.1016/S0092-8674(00)80217-2
Repression by Ume6 Involves Recruitment of a Complex Containing Sin3 Corepressor and Rpd3 Histone Deacetylase to Target Promoters
resolves10.1093/emboj/17.2.520
Distinct requirements for chromatin assembly in transcriptional repression by thyroid hormone receptor and histone deacetylase
resolves10.1093/nar/21.21.4886
Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2
resolves10.1128/MCB.14.8.5487
Dependence of transcriptional repression on CpG methylation density.
resolves10.1128/MCB.13.12.7372
Inactive chromatin spreads from a focus of methylation.
resolves10.1016/0092-8674(92)90561-P
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
resolves10.1073/pnas.80.16.4919
Methylation of replicating and post-replicated mouse L-cell DNA.
resolves10.1038/35257
The cancer-chromatin connection
resolves10.1074/jbc.271.40.24325
Nucleosome Assembly on Methylated CGG Triplet Repeats in the Fragile X Mental Retardation Gene 1 Promoter
resolves10.1006/jmbi.1997.0899
CpG methylation remodels chromatin structure in vitro
The 7 references without a DOI — listed, not checked
no DOI — not checkedAntequera, F. Boyes, J. Bird, A. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell 62, 503–514 (1990).
no DOI — not checkedGonzalez-Zulueta, M. et al. Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res. 55, 4531–4535 (1995).
no DOI — not checkedMerlo, A. et al. 5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nature Med. 1, 686–692 (1995).
no DOI — not checkedAlland, L. et al. Role of NCoR and histone deacetylase in Sin3-mediated transcriptional and oncogenic repression. Nature 387, 49–55 (1997).
no DOI — not checkedHeinzel, T. et al. N-CoR, mSIN3, and histone deacetylase in a complex required for repression by nuclear receptors and Mad. Nature 387, 43–48 (1997).
no DOI — not checkedLandsberger, N. Wolffe, A.P. The role of chromatin and Xenopus heat shock transcription factor (XHSF1) in the regulation of the Xenopus hsp70 promoter in vivo. Mol. Cell. Biol. 15, 6013–6024 (1995).
no DOI — not checkedLandsberger, N. Wolffe, A.P. Remodeling of regulatory nucleoprotein complexes on the Xenopus hsp70 promoter during meiotic maturation of the Xenopus oocyte. EMBO J. 16, 4361–4373 (1997).
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-08-12 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.1038/561"><img src="https://citestamp.com/citestamped/10.1038/561/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.1038/561/badge.svg)](https://citestamp.com/citestamped/10.1038/561)