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SCFSlmb E3 ligase-mediated degradation of Expanded is inhibited by the Hippo pathway in Drosophila
56/56 checkable references clean · checked 2026-07-22
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
The 56 checked references that resolve
resolves10.1016/S0092-8674(03)00557-9
The Drosophila Mst Ortholog, hippo, Restricts Growth and Cell Proliferation and Promotes Apoptosis
resolves10.1038/ncb1050
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
resolves10.1016/S0092-8674(03)00549-X
hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell Proliferation and Promotes Apoptosis in Conjunction with salvador and warts
resolves10.1016/j.cell.2004.12.036
Control of Cell Proliferation and Apoptosis by Mob as Tumor Suppressor, Mats
resolves10.1101/gad.1134003
The <i>Drosophila</i> Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
resolves10.1016/j.cell.2006.07.013
The Hippo Pathway Regulates the bantam microRNA to Control Cell Proliferation and Apoptosis in Drosophila
resolves10.1038/ncb1339
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
resolves10.1016/j.devcel.2009.12.011
Kibra Is a Regulator of the Salvador/Warts/Hippo Signaling Network
resolves10.1016/j.devcel.2009.12.013
The WW Domain Protein Kibra Acts Upstream of Hippo in Drosophila
resolves10.1016/j.devcel.2009.12.012
Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded
resolves10.1016/j.devcel.2012.03.013
Growth Control by Committee: Intercellular Junctions, Cell Polarity, and the Cytoskeleton Regulate Hippo Signaling
resolves10.1016/j.cub.2006.09.045
Fat Cadherin Modulates Organ Size in Drosophila via the Salvador/Warts/Hippo Signaling Pathway
resolves10.1016/j.cub.2006.09.004
The Tumor-Suppressor Gene fat Controls Tissue Growth Upstream of Expanded in the Hippo Signaling Pathway
resolves10.1016/j.cub.2006.09.005
The Fat Cadherin Acts through the Hippo Tumor-Suppressor Pathway to Regulate Tissue Size
resolves10.1073/pnas.1004060107
The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in
<i>Drosophila</i>
resolves10.1016/j.cub.2010.01.055
Lgl, aPKC, and Crumbs Regulate the Salvador/Warts/Hippo Pathway through Two Distinct Mechanisms
resolves10.1073/pnas.1004279107
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
resolves10.1016/j.cub.2010.03.019
Crumbs Regulates Salvador/Warts/Hippo Signaling in Drosophila via the FERM-Domain Protein Expanded
resolves10.1016/j.devcel.2011.12.011
The Cell Adhesion Molecule Echinoid Functions as a Tumor Suppressor and Upstream Regulator of the Hippo Signaling Pathway
resolves10.1016/j.jgg.2012.05.009
A Systematic Phenotypic Screen of F-box Genes Through a Tissue-specific RNAi-based Approach in Drosophila
resolves10.1083/jcb.200808049
The SCFSlimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication
resolves10.1016/j.devcel.2008.01.007
The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway
resolves10.1016/S0925-4773(00)00256-2
Drosophila null slimb clones transiently deregulate Hedgehog-independent transcription of wingless in all limb discs, and induce decapentaplegic transcription linked to imaginal disc regeneration
resolves10.1016/j.cub.2012.02.050
Mutual Repression by Bantam miRNA and Capicua Links the EGFR/MAPK and Hippo Pathways in Growth Control
resolves10.1038/35154
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb
resolves10.1242/dev.127.6.1315
The <i>Neurofibromatosis-2</i> homologue, <i>Merlin</i>, and the tumor suppressor <i>expanded</i> function together in <i>Drosophila</i> to regulate cell proliferation and differentiation
resolves10.1101/gad.9.12.1530
Dachsous encodes a member of the cadherin superfamily that controls imaginal disc morphogenesis in Drosophila.
resolves10.1242/dev.121.9.2767
<i>four-jointed</i> is required for intermediate growth in the proximal-distal axis in <i>Drosophila</i>
resolves10.1006/dbio.1996.0038
Positional Information along the Dorsal–Ventral Axis of theDrosophilaEye: Graded Expression of thefour-jointedGene
resolves10.1016/j.devcel.2008.06.003
Morphogen Control of Wing Growth through the Fat Signaling Pathway
resolves10.1371/journal.pbio.1000386
A Feed-Forward Circuit Linking Wingless, Fat-Dachsous Signaling, and the Warts-Hippo Pathway to Drosophila Wing Growth
resolves10.1016/j.devcel.2010.11.007
Antagonistic Growth Regulation by Dpp and Fat Drives Uniform Cell Proliferation
resolves10.1016/j.cub.2010.04.016
Modulation of Fat:Dachsous Binding by the Cadherin Domain Kinase Four-Jointed
resolves10.1073/pnas.1315508111
Crumbs promotes expanded recognition and degradation by the SCF
<sup>Slimb/β-TrCP</sup>
ubiquitin ligase
resolves10.1074/jbc.M110.152942
The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase
resolves10.1101/gad.1843810
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF<sup>β-TRCP</sup>
resolves10.1038/nrc2396
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer
resolves10.1038/sj.onc.1207389
The many faces of β-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer
resolves10.1016/S0092-8674(00)80292-5
Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor
resolves10.1242/jcs.041806
The Hippo pathway regulates apical-domain size independently of its growth-control function
resolves10.1073/pnas.1017548108
<i>Drosophila</i>
homeodomain-interacting protein kinase inhibits the Skp1-Cul1-F-box E3 ligase complex to dually promote Wingless and Hedgehog signaling
resolves10.1371/journal.pone.0036362
Uif, a Large Transmembrane Protein with EGF-Like Repeats, Can Antagonize Notch Signaling in Drosophila
resolves10.1016/j.devcel.2011.08.028
Tao-1 Phosphorylates Hippo/MST Kinases to Regulate the Hippo-Salvador-Warts Tumor Suppressor Pathway
resolves10.1371/journal.pgen.1000142
Efficient Genetic Method for Establishing Drosophila Cell Lines Unlocks the Potential to Create Lines of Specific Genotypes
resolves10.1091/mbc.e12-10-0772
The<i>Drosophila</i>F-box protein dSkp2 regulates cell proliferation by targeting Dacapo for degradation
resolves10.1128/MCB.01876-08
A Bifunctional Regulatory Element in Human Somatic Wee1 Mediates Cyclin A/Cdk2 Binding and Crm1-Dependent Nuclear Export
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