Reference health

Many roads to maturity: microRNA biogenesis pathways and their regulation

2 of 122 checkable references need attention · checked 2026-07-23

At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.

References needing attention

marked retracted — notice via Crossref, record curated by Retraction Watch10.1096/fj.06-6130com

Retracted: Post‐transcriptional regulation of the let‐7 microRNA during neural cell specification

marked retracted — notice via Crossref, record curated by Retraction Watch10.1038/ncb1577

DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs

The 120 checked references that resolve

resolves10.1016/S0092-8674(04)00045-5

MicroRNAs

resolves10.1126/science.1073827

A microRNA in a Multiple-Turnover RNAi Enzyme Complex

resolves10.1126/science.1102513

Argonaute2 Is the Catalytic Engine of Mammalian RNAi

resolves10.1016/j.molcel.2004.07.007

Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs

resolves10.1261/rna.7131604

Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis

resolves10.1016/j.cell.2007.12.024

Getting to the Root of miRNA-Mediated Gene Silencing

resolves10.1038/nrg2290

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

resolves10.1038/nature07242

The impact of microRNAs on protein output

resolves10.1038/nature07228

Widespread changes in protein synthesis induced by microRNAs

resolves10.1016/0092-8674(93)90529-Y

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

resolves10.1016/0092-8674(93)90530-4

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

resolves10.1101/gad.1248505

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

resolves10.1126/science.1114519

MicroRNA Expression in Zebrafish Embryonic Development

resolves10.1016/j.cell.2005.01.014

RAS Is Regulated by the let-7 MicroRNA Family

resolves10.1038/nature03702

MicroRNA expression profiles classify human cancers

resolves10.1038/nature03552

A microRNA polycistron as a potential human oncogene

resolves10.1038/nature03677

c-Myc-regulated microRNAs modulate E2F1 expression

resolves10.1038/nrc1997

MicroRNA signatures in human cancers

resolves10.1038/nature05939

A microRNA component of the p53 tumour suppressor network

resolves10.1126/science.1137999

Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation

resolves10.1038/ng2003

Impaired microRNA processing enhances cellular transformation and tumorigenesis

resolves10.1261/rna.2322506

Post-transcriptional regulation of microRNA expression

resolves10.1016/j.ydbio.2004.02.019

Human embryonic stem cells express a unique set of microRNAs

resolves10.1101/gad.1444406

Extensive post-transcriptional regulation of microRNAs and its implications for cancer

resolves10.1261/rna.804508

Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors

resolves10.1038/sj.emboj.7600385

MicroRNA genes are transcribed by RNA polymerase II

resolves10.1261/rna.7135204

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

resolves10.1038/nsmb1167

RNA polymerase III transcribes human microRNAs

resolves10.1016/j.ccr.2006.04.020

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

resolves10.1158/0008-5472.CAN-06-4074

The Human let-7a-3 Locus Contains an Epigenetically Regulated MicroRNA Gene with Oncogenic Function

resolves10.1073/pnas.0803055105

A microRNA DNA methylation signature for human cancer metastasis

resolves10.1371/journal.pone.0003574

MiR-433 and miR-127 Arise from Independent Overlapping Primary Transcripts Encoded by the miR-433-127 Locus

resolves10.1158/0008-5472.CAN-06-0537

Sequence Variations of MicroRNAs in Human Cancer: Alterations in Predicted Secondary Structure Do Not Affect Processing

resolves10.1016/j.ccr.2006.01.025

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

resolves10.1038/nature01957

The nuclear RNase III Drosha initiates microRNA processing

resolves10.1038/nature03049

Processing of primary microRNAs by the Microprocessor complex

resolves10.1038/nature03120

The Microprocessor complex mediates the genesis of microRNAs

resolves10.1101/gad.1262504

The Drosha-DGCR8 complex in primary microRNA processing

resolves10.1016/j.cub.2004.11.001

The Human DiGeorge Syndrome Critical Region Gene 8 and Its D. melanogaster Homolog Are Required for miRNA Biogenesis

resolves10.1016/j.cell.2006.03.043

Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex

resolves10.1261/rna.2780503

Sequence requirements for micro RNA processing and function in human cells

resolves10.1074/jbc.M504714200

Efficient Processing of Primary microRNA Hairpins by Drosha Requires Flanking Nonstructured RNA Sequences

resolves10.1093/hmg/ddm062

Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA

resolves10.1038/sj.emboj.7601512

Processing of intronic microRNAs

resolves10.1038/nsmb.1475

Primary microRNA transcripts are processed co-transcriptionally

resolves10.1038/nsmb1250

The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a

resolves10.1016/j.molcel.2008.10.013

Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops

resolves10.1038/nature07086

SMAD proteins control DROSHA-mediated microRNA maturation

resolves10.1016/j.cell.2007.06.028

The Mirtron Pathway Generates microRNA-Class Regulatory RNAs in Drosophila

resolves10.1038/nature05983

Intronic microRNA precursors that bypass Drosha processing

resolves10.1016/j.molcel.2007.09.028

Mammalian Mirtron Genes

resolves10.1126/science.1154040

Selective Blockade of MicroRNA Processing by Lin28

resolves10.1038/ncb1759

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

resolves10.1261/rna.1155108

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

resolves10.1074/jbc.C800108200

Determinants of MicroRNA Processing Inhibition by the Developmentally Regulated RNA-binding Protein Lin28

resolves10.1016/j.molcel.2008.09.014

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

resolves10.1093/nar/gkl458

Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing

resolves10.1016/j.cell.2008.10.053

Posttranscriptional Crossregulation between Drosha and DGCR8

resolves10.1101/gad.1158803

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

resolves10.1261/rna.5167604

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

resolves10.1126/science.1090599

Nuclear Export of MicroRNA Precursors

resolves10.1101/sqb.2006.71.050

Substrate Selectivity of Exportin 5 and Dicer in the Biogenesis of MicroRNAs

resolves10.1093/nar/gkh824

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5

resolves10.1016/j.cell.2005.10.022

Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing

resolves10.1038/sj.embor.7400509

TRBP, a regulator of cellular PKR and HIV‐1 virus expression, interacts with Dicer and functions in RNA silencing

resolves10.1038/sj.emboj.7600942

The role of PACT in the RNA silencing pathway

resolves10.1073/pnas.0710869105

In vitro reconstitution of the human RISC-loading complex

resolves10.1038/nature03868

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

resolves10.1101/gad.1384005

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

resolves10.1016/j.cell.2007.10.032

Dual Role for Argonautes in MicroRNA Processing and Posttranscriptional Regulation of MicroRNA Expression

resolves10.1016/j.cell.2005.08.044

Passenger-Strand Cleavage Facilitates Assembly of siRNA into Ago2-Containing RNAi Enzyme Complexes

resolves10.1101/gad.1370605

Slicer function of Drosophila Argonautes and its involvement in RISC formation

resolves10.1016/j.cell.2005.10.020

Argonaute2 Cleaves the Anti-Guide Strand of siRNA during RISC Activation

resolves10.1038/sj.embor.7400637

Cleavage of the siRNA passenger strand during RISC assembly in human cells

resolves10.1261/rna.283207

Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes

resolves10.1101/gad.1210204

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

resolves10.1016/j.cell.2006.09.033

Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi

resolves10.1038/35053110

Role for a bidentate ribonuclease in the initiation step of RNA interference

resolves10.1016/S0092-8674(01)00431-7

Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing

resolves10.1126/science.1062961

A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA

resolves10.1101/gad.927801

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

resolves10.1038/ng1253

Dicer is essential for mouse development

resolves10.1016/j.cell.2008.02.034

Sorting of Small RNAs into Arabidopsis Argonaute Complexes Is Directed by the 5′ Terminal Nucleotide

resolves10.1016/j.jmb.2008.05.005

Autoinhibition of Human Dicer by Its Internal Helicase Domain

resolves10.1073/pnas.0803230105

A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

resolves10.1016/j.cub.2005.07.029

Methylation Protects miRNAs and siRNAs from a 3′-End Uridylation Activity in Arabidopsis

resolves10.1126/science.1102755

A Protein Sensor for siRNA Asymmetry

resolves10.1016/j.cub.2005.10.048

Identification of Novel Argonaute-Associated Proteins

resolves10.1371/journal.pbio.0040210

Translation Repression in Human Cells by MicroRNA-Induced Gene Silencing Requires RCK/p54

resolves10.1074/jbc.M705054200

P68 RNA Helicase Unwinds the Human let-7 MicroRNA Precursor Duplex and Is Required for let-7-directed Silencing of Gene Expression

resolves10.1016/j.molcel.2007.04.016

RNA Helicase A Interacts with RISC in Human Cells and Functions in RISC Loading

resolves10.1016/S0092-8674(03)00759-1

Asymmetry in the Assembly of the RNAi Enzyme Complex

resolves10.1016/S0092-8674(03)00801-8

Functional siRNAs and miRNAs Exhibit Strand Bias

resolves10.1016/j.cell.2007.05.056

Drosophila microRNAs Are Sorted into Functionally Distinct Argonaute Complexes after Production by Dicer-1

resolves10.1016/j.cell.2007.05.057

Sorting of Drosophila Small Silencing RNAs

resolves10.1016/j.cub.2007.12.049

Argonaute Loading Improves the 5′ Precision of Both MicroRNAs and Their miRNA∗ Strands in Flies

resolves10.1101/gad.1565607

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway

resolves10.1073/pnas.0800803105

Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites

resolves10.1038/nature07186

Prolyl 4-hydroxylation regulates Argonaute 2 stability

resolves10.1042/BJ20080599

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

resolves10.1038/ncb1274

MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

resolves10.1038/ncb1265

Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

resolves10.1126/science.1136235

A Hexanucleotide Element Directs MicroRNA Nuclear Import

resolves10.1126/science.1157647

An Argonaute Transports siRNAs from the Cytoplasm to the Nucleus

resolves10.1016/j.cell.2008.12.023

Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs

resolves10.1073/pnas.0808830105

MicroRNA-directed transcriptional gene silencing in mammalian cells

resolves10.1073/pnas.0707594105

MicroRNA-373 induces expression of genes with complementary promoter sequences

resolves10.1126/science.1163728

Degradation of microRNAs by a Family of Exoribonucleases in Arabidopsis

resolves10.1038/nature06205

Interferon modulation of cellular microRNAs as an antiviral mechanism

resolves10.1016/j.cell.2007.11.034

RNA-Binding Protein Dnd1 Inhibits MicroRNA Access to Target mRNA

resolves10.1038/nature05954

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

resolves10.1126/science.1151526

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

resolves10.1111/j.1349-7006.2005.00015.x

Reduced expression of Dicer associated with poor prognosis in lung cancer patients

resolves10.1261/rna.7350304

RNA editing of a miRNA precursor: FIGURE 1.

resolves10.1186/gb-2006-7-4-r27

RNA editing of human microRNAs

resolves10.1038/nsmb1041

Modulation of microRNA processing and expression through RNA editing by ADAR deaminases

resolves10.1038/nsmb936

The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage

resolves10.1093/nar/gkn479

Frequency and fate of microRNA editing in human brain

resolves10.1038/sj.embor.7401011

RNA editing of the microRNA‐151 precursor blocks cleavage by the Dicer–TRBP complex

resolves10.1126/science.1138050

Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs

What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-07-23 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

view as graph · paper page

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.1038/ncb0309-228"><img src="https://citestamp.com/citestamped/10.1038/ncb0309-228/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>

[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.1038/ncb0309-228/badge.svg)](https://citestamp.com/citestamped/10.1038/ncb0309-228)