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PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE
42/42 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
The 42 checked references that resolve
resolves10.1016/j.devcel.2006.09.023
Migration of Zebrafish Primordial Germ Cells: A Role for Myosin Contraction and Cytoplasmic Flow
resolves10.1038/ncb1019
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
resolves10.1126/science.273.5272.245
Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)
resolves10.1016/j.cub.2006.05.065
ROCK- and Myosin-Dependent Matrix Deformation Enables Protease-Independent Tumor-Cell Invasion In Vivo
resolves10.1128/MCB.20.24.9364-9375.2000
Induced Expression of Rnd3 Is Associated with Transformation of Polarized Epithelial Cells by the Raf–MEK–Extracellular Signal-Regulated Kinase Pathway
resolves10.1083/jcb.141.1.187
A New Member of the Rho Family, Rnd1, Promotes Disassembly of Actin Filament Structures and Loss of Cell Adhesion
resolves10.1083/jcb.200509075
Paxillin phosphorylation at Ser273 localizes a GIT1–PIX–PAK complex and regulates adhesion and protrusion dynamics
resolves10.1091/mbc.01-10-0490
Small GTP-binding Protein TC10 Differentially Regulates Two Distinct Populations of Filamentous Actin in 3T3L1 Adipocytes
resolves10.1101/gad.894301
<i>Wrch-1</i>, a novel member of the Rho gene family that is regulated by Wnt-1
resolves10.1242/jcs.00208
Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth
resolves10.1101/gad.424807
Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion
resolves10.1074/jbc.M001908200
Threonine Phosphorylation of the β3 Integrin Cytoplasmic Tail, at a Site Recognized by PDK1 and Akt/PKB in Vitro, Regulates Shc Binding
resolves10.1038/ncb1230
Cdc42–MRCK and Rho–ROCK signalling cooperate in myosin phosphorylation and cell invasion
resolves10.1083/jcb.200412043
The Rho kinases I and II regulate different aspects of myosin II activity
resolves10.1158/0008-5472.CAN-04-2052
Conditional ROCK Activation <b>
<i>In vivo</i>
</b> Induces Tumor Cell Dissemination and Angiogenesis
resolves10.1128/MCB.16.10.5313
The p160 RhoA-Binding Kinase ROKα Is a Member of a Kinase Family and Is Involved in the Reorganization of the Cytoskeleton
resolves10.1038/sj.onc.1208147
Roles of PDK-1 and PKN in regulating cell migration and cortical actin formation of PTEN-knockout cells
resolves10.1186/1471-2407-6-77
3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases
resolves10.1161/01.RES.0000126848.54740.4A
Phosphoinositide-Dependent Kinase 1 and p21-Activated Protein Kinase Mediate Reactive Oxygen Species–Dependent Regulation of Platelet-Derived Growth Factor–Induced Smooth Muscle Cell Migration
resolves10.1038/sj.bjc.6600510
Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters
resolves10.1038/5587
An essential part for Rho–associated kinase in the transcellular invasion of tumor cells
resolves10.1158/0008-5472.CAN-04-1136
Identification and Testing of a Gene Expression Signature of Invasive Carcinoma Cells within Primary Mammary Tumors
resolves10.1002/j.1460-2075.1996.tb00574.x
Rho‐associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.
resolves10.1002/j.1460-2075.1996.tb00539.x
The small GTP‐binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.
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