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Contemporary strategies for peptide macrocyclization
1 of 108 checkable references need attention · checked 2026-07-22
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
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References needing attention
does not resolve to a known work10.1007/BF02442590
The 107 checked references that resolve
resolves10.1038/nrd2590
The exploration of macrocycles for drug discovery — an underexploited structural class
resolves10.1002/bip.21372
Invited reviewnative chemical ligation applied to the synthesis and bioengineering of circular peptides and proteins
resolves10.2174/138527208786241501
Recent Progress of Synthetic Studies to Peptide and Peptidomimetic Cyclization
resolves10.1016/j.jbiotec.2004.03.015
An improved method for the solution cyclization of peptides under pseudo-high dilution conditions
resolves10.1021/ja00497a032
Chemistry of polymer-bound o-benzyne. Frequency of encounter between substituents on crosslinked polystyrenes
resolves10.1016/0040-4039(93)85003-F
A novel, convenient, three-dimensional orthogonal strategy for solid-phase synthesis of cyclic peptides
resolves10.1002/psc.512
On‐resin head‐to‐tail cyclization of cyclotetrapeptides: optimization of crucial parameters
resolves10.1002/anie.200461656
Head‐to‐Tail Peptide Cyclodimerization by Copper‐Catalyzed Azide–Alkyne Cycloaddition
resolves10.1111/j.1399-3011.1997.tb01122.x
Cyclotetrapeptides and cyclopentapeptides: occurrence and synthesis*
resolves10.1021/cr950005s
Chemical Synthesis of Natural Product Peptides: Coupling Methods for the Incorporation of Noncoded Amino Acids into Peptides
resolves10.1021/ja00049a021
Prediction of the best linear precursor in the synthesis of cyclotetrapeptides by molecular mechanic calculations
resolves10.1371/journal.pcbi.1000645
Hydrogen-Bond Driven Loop-Closure Kinetics in Unfolded Polypeptide Chains
resolves10.1002/anie.196503561
Synthesis of Cyclotri‐<scp>L</scp>‐prolyl, a Cyclotripeptide Having a Nine‐Membered Ring
resolves10.1021/ja984016p
Structural Mimicry of Canonical Conformations in Antibody Hypervariable Loops Using Cyclic Peptides Containing a Heterochiral Diproline Template
resolves10.1111/j.1399-3011.1992.tb01553.x
Cyclic hexapeptides derived from the human thymopoietin III
resolves10.1021/ja00076a005
Biomimetic synthesis of gramicidin S. Direct formation of the antibiotic from pentapeptide active esters having no protecting group on the side chain of the Orn residue
resolves10.1021/jo01332a003
Practical synthesis of cyclic peptides, with an example of dependence of cyclization yield upon linear sequence
resolves10.1021/jo951108d
Cyclization of<i>all</i>-<scp>l</scp>-Pentapeptides by Means of 1-Hydroxy-7-azabenzotriazole-Derived Uronium and Phosphonium Reagents
resolves10.1007/s10822-009-9295-y
Modeling of peptides containing D-amino acids: implications on cyclization
resolves10.1021/ja970855k
Conformational Analysis of Reverse-Turn Constraints by N-Methylation and N-Hydroxylation of Amide Bonds in Peptides and Non-Peptide Mimetics
resolves10.1002/chem.200701029
Conformational Preference and Potential Templates of <i>N</i>‐Methylated Cyclic Pentaalanine Peptides
resolves10.1021/ja017160a
Kinetic Control of Proline Amide Rotamers: Total Synthesis of <i>trans,trans</i>- and <i>cis,cis</i>-Ceratospongamide
resolves10.1021/ja961509q
Pseudo-Prolines as a Solubilizing, Structure-Disrupting Protection Technique in Peptide Synthesis
resolves10.1021/ja962780a
Pseudo-Prolines as a Molecular Hinge: Reversible Induction of<i>cis</i>Amide Bonds into Peptide Backbones
resolves10.1016/S0040-4020(99)00650-X
Pseudo-prolines in cyclic peptides: Conformational stabilisation of cyclo[Pro-Thr(ψMe,Mepro)-Pro]
resolves10.1021/jo0484732
Pseudoprolines as Removable Turn Inducers: Tools for the Cyclization of Small Peptides
resolves10.1021/ol101018w
Synthesis of All-<scp>l</scp>Cyclic Tetrapeptides Using Pseudoprolines as Removable Turn Inducers
resolves10.1021/jo052027c
Carbosilane Dendrimeric Carbodiimides: Site Isolation as a Lactamization Tool
resolves10.1039/b813439a
Molecularly imprinted cavities template the macrocyclization of tetrapeptides
resolves10.1021/mp700137g
Nonribosomal Peptide Synthetases Involved in the Production of Medically Relevant Natural Products
resolves10.1021/cb700233t
Reprogramming the Translation Initiation for the Synthesis of Physiologically Stable Cyclic Peptides
resolves10.1002/(SICI)1521-3773(19980504)37:8<1086::AID-ANIE1086>3.0.CO;2-V
Facile Synthesis of Cyclic Tetrapeptides from Nonactivated Peptide Esters on Metal Centers
resolves10.1002/hlca.19890720502
Solubilization of Peptides in Non‐polar Organic Solvents by the Addition of Inorganic Salts: Facts and Implications
resolves10.1034/j.1399-3011.2000.00734.x
Selective and facile cyclization of <i>N</i>‐chloroacetylated peptides from the C4 domain of HIV Gp120 in LiCl/DMF solvent systems
resolves10.1073/pnas.78.7.4055
New segment-coupling method for peptide synthesis in aqueous solution: application to synthesis of human [Gly17]-beta-endorphin.
resolves10.1021/ja983859d
Lactone and Lactam Library Synthesis by Silver Ion-Assisted Orthogonal Cyclization of Unprotected Peptides
resolves10.1021/cc900100z
Synthesis of Cyclic Peptides through Direct Aminolysis of Peptide Thioesters Catalyzed by Imidazole in Aqueous Organic Solutions
resolves10.1021/ol100596p
Macrolactonization of Peptide Thioesters Catalyzed by Imidazole and Its Application in the Synthesis of Kahalalide B and Analogues
resolves10.1021/ja954278g
Cyclic Peptides from Linear Unprotected Peptide Precursors through Thiazolidine Formation
resolves10.1021/ja9621105
Synthesis and Application of Unprotected Cyclic Peptides as Building Blocks for Peptide Dendrimers
resolves10.1021/jo049839d
On-Resin Native Chemical Ligation for Cyclic Peptide Synthesis<sup>1</sup><sup>,</sup><sup>2</sup>
resolves10.1002/1521-3773(20011001)40:19<3625::AID-ANIE3625>3.0.CO;2-Q
Design and Synthesis of a Protein Catenane This work was supported by The Skaggs Institute for Chemical Biology, The Sloan Foundation, and NIH-GM570132 (PED). We thank Dr. Songpong Deechongkit for assistance with the analytical ultracentrifuge and CD measurements.
resolves10.1021/ja984480u
Thia Zip Reaction for Synthesis of Large Cyclic Peptides: Mechanisms and Applications
resolves10.1021/ja003265m
Synthesis of Peptides and Proteins without Cysteine Residues by Native Chemical Ligation Combined with Desulfurization
resolves10.1021/ja992173y
Synthesis of Difficult Cyclic Peptides by Inclusion of a Novel Photolabile Auxiliary in a Ring Contraction Strategy
resolves10.1039/b800464a
Cyclic tetrapeptides via the ring contraction strategy: chemical techniques useful for their identification
resolves10.1021/ol034907o
Difficult Macrocyclizations: New Strategies for Synthesizing Highly Strained Cyclic Tetrapeptides
resolves10.1021/ja962260f
Conformational Control by Thiazole and Oxazoline Rings in Cyclic Octapeptides of Marine Origin. Novel Macrocyclic Chair and Boat Conformations
resolves10.1021/jo011148j
Peptidotriazoles on Solid Phase: [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides
resolves10.1002/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4
A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes
resolves10.1021/ol053095o
Click Chemistry as a Route to Cyclic Tetrapeptide Analogues: Synthesis of<i>c</i><i>yclo</i>-[Pro-Val-ψ(triazole)-Pro-Tyr]
resolves10.1039/b616751a
1,2,3-Triazoles as peptide bond isosteres: synthesis and biological evaluation of cyclotetrapeptide mimics
resolves10.1021/ol702228u
Click Chemistry as a Macrocyclization Tool in the Solid-Phase Synthesis of Small Cyclic Peptides
resolves10.1021/ol0518028
Efficient Route to<i>C</i><sub>2</sub>Symmetric Heterocyclic Backbone Modified Cyclic Peptides
resolves10.1002/anie.200805901
Conformationally Homogeneous Heterocyclic Pseudotetrapeptides as Three‐Dimensional Scaffolds for Rational Drug Design: Receptor‐Selective Somatostatin Analogues
resolves10.1021/ja075865s
Protein Prosthesis: 1,5-Disubstituted[1,2,3]triazoles as <i>cis</i>-Peptide Bond Surrogates
resolves10.1002/anie.200805900
Probing the Bioactive Conformation of an Archetypal Natural Product HDAC Inhibitor with Conformationally Homogeneous Triazole‐Modified Cyclic Tetrapeptides
resolves10.1002/anie.200904980
Cyclative Cleavage through Dipolar Cycloaddition: Polymer‐Bound Azidopeptidylphosphoranes Deliver Locked <i>cis‐</i>Triazolylcyclopeptides as Privileged Protein Binders
resolves10.1021/ja961626l
Application of Ring-Closing Metathesis to the Synthesis of Rigidified Amino Acids and Peptides
resolves10.1002/(SICI)1521-3773(19981217)37:23<3281::AID-ANIE3281>3.0.CO;2-V
Highly Efficient Synthesis of Covalently Cross-Linked Peptide Helices by Ring-Closing Metathesis
resolves10.1021/ja000563a
An All-Hydrocarbon Cross-Linking System for Enhancing the Helicity and Metabolic Stability of Peptides
resolves10.1021/ja0466659
A Highly Stable Short α-Helix Constrained by a Main-Chain Hydrogen-Bond Surrogate
resolves10.1021/ja062710w
Evaluation of Biologically Relevant Short α-Helices Stabilized by a Main-Chain Hydrogen-Bond Surrogate
resolves10.1021/ol702521g
Design and Synthesis of Cyclic RGD Pentapeptoids by Consecutive Ugi Reactions
resolves10.1039/b210952b
Via Ugi reactions to conformationally fixed cyclic peptidesDedicated to Professor Dr D. Seebach on the occasion of his 65th birthday.
resolves10.1021/ja100517v
Total Synthesis of Cyclosporine: Access to N-Methylated Peptides via Isonitrile Coupling Reactions
resolves10.1021/ja028485+
Highly Stable Self-Assembly in Water: Ion Pair Driven Dimerization of a Guanidiniocarbonyl Pyrrole Carboxylate Zwitterion
resolves10.1021/ja805649f
Translation of DNA into a Library of 13 000 Synthetic Small-Molecule Macrocycles Suitable for <i>in Vitro</i> Selection
resolves10.1021/ja063722k
High-Throughput Sequence Determination of Cyclic Peptide Library Members by Partial Edman Degradation/Mass Spectrometry
resolves10.1039/b415578e
Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy
resolves10.1002/anie.201001604
Synchronized Synthesis of Peptide‐Based Macrocycles by Digital Microfluidics
The 3 references without a DOI — listed, not checked
no DOI — not checkedGilon, C., Mang, C., Lohorf, E., Friedler, A. & Kessler, H. Synthesis of Peptides and Peptidomimetics E22b Ch. 6.8 (Thieme, 2004)
no DOI — not checkedLiu, M. et al. Cyclization of several linear penta- and heptapeptides with different metal ions studied by CD spectroscopy. J. Pept. Sci. 65, 55–64 (2005).
no DOI — not checkedHuisgen, R. Centenary lecture: 1,3-Dipolar cycloadditions. Proc. Chem. Soc. Lond. 357–369 (1961).
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