Reference health
Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
43/43 checkable references clean · checked 2026-09-08
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
9 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 43 checked references that resolve
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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
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Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus
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Cut-like Homeobox 1 (CUX1) Regulates Expression of the Fat Mass and Obesity-associated and Retinitis Pigmentosa GTPase Regulator-interacting Protein-1-like (RPGRIP1L) Genes and Coordinates Leptin Receptor Signaling
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Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children
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Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry
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Physical Activity Attenuates the Genetic Predisposition to Obesity in 20,000 Men and Women from EPIC-Norfolk Prospective Population Study
resolves10.3945/jn.111.153460
High Dietary Saturated Fat Intake Accentuates Obesity Risk Associated with the Fat Mass and Obesity-Associated Gene in Adults
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Dietary fatty acid distribution modifies obesity risk linked to the rs9939609 polymorphism of the fat mass and obesity-associated gene in a Spanish case–control study of children
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A High Intake of Saturated Fatty Acids Strengthens the Association between the Fat Mass and Obesity-Associated Gene and BMI
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Fried food consumption, genetic risk, and body mass index: gene-diet interaction analysis in three US cohort studies
resolves10.1093/hmg/ddu411
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals
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Physical activity attenuates the body mass index–increasing influence of genetic variation in the FTO gene
resolves10.1007/s00109-009-0451-6
Combined effects of MC4R and FTO common genetic variants on obesity in European general populations
resolves10.2337/db07-0910
Low Physical Activity Accentuates the Effect of the <i>FTO</i> rs9939609 Polymorphism on Body Fat Accumulation
resolves10.1001/archpediatrics.2010.29
Attenuation of the Effect of the FTO rs9939609 Polymorphism on Total and Central Body Fat by Physical Activity in Adolescents
resolves10.1038/ejhg.2010.131
FTO genotype and adiposity in children: physical activity levels influence the effect of the risk genotype in adolescent males
resolves10.3945/ajcn.2009.27958
Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity
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Drinking Patterns and Body Mass Index in Never Smokers: National Health Interview Survey, 1997-2001
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Inverse association of the obesity predisposing
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rs9939609 genotype with alcohol consumption and risk for alcohol dependence
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Short Sleep Duration Is Associated with Reduced Leptin, Elevated Ghrelin, and Increased Body Mass Index
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The 9 references without a DOI — listed, not checked
no DOI — not checkedUK Biobank. UK Biobank Website. Available at http://www.ukbiobank.ac.uk/ (2016).
no DOI — not checkedUK Biobank. Genotyping and quality control of UK Biobank, a large-scale, extensively phenotyped prospective resource. Available at http://biobank.ctsu.ox.ac.uk/crystal/docs/genotyping_qc.pdf (2015).
no DOI — not checkedUK Biobank. Genotype imputation and genetic association studies of UK Biobank Interim Data Release. Available at http://biobank.ctsu.ox.ac.uk/crystal/docs/impute_ukb_v1.pdf1–14 (2015).
no DOI — not checkedUK Biobank. UK Biobank Anthropometry. Available at http://biobank.ctsu.ox.ac.uk/crystal/docs/Anthropometry.pdf (2014).
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no DOI — not checkedR Core Team. R: A Language and Environment for Statistical Computing. Available at http://www.r-project.org/ (2015).
no DOI — not checkedUK Biobank. UK Biobank 24-hour dietary recall questionnaire. Available at http://biobank.ctsu.ox.ac.uk/crystal/docs/DietWebQ.pdf (2012).
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no DOI — not checkedInternational Stroke Genetics Consortium (ISGC). et al. Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat. Genet. 44, 328–333 (2012).
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