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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

https://doi.org/10.1038/ni1243
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38/38 checkable references clean · checked 2026-07-23

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

The 38 checked references that resolve
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Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling
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Toll/IL-1 Receptor Domain-Containing Adaptor Inducing IFN-β (TRIF) Associates with TNF Receptor-Associated Factor 6 and TANK-Binding Kinase 1, and Activates Two Distinct Transcription Factors, NF-κB and IFN-Regulatory Factor-3, in the Toll-Like Receptor Signaling
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RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation
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Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
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Differential involvement of IFN-  in Toll-like receptor-stimulated dendritic cell activation
resolves10.1038/ni1118
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
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Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction
resolves10.1126/science.1087262
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
resolves10.1038/ni1010
Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways
resolves10.1084/jem.20040520
The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection
resolves10.1084/jem.20040528
Differential Requirement for TANK-binding Kinase-1 in Type I Interferon Responses to Toll-like Receptor Activation and Viral Infection
resolves10.1073/pnas.2237236100
IFN-regulatory factor 3-dependent gene expression is defective in <i>Tbk1</i> -deficient mouse embryonic fibroblasts
resolves10.1038/ni1087
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
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Cell Type-Specific Involvement of RIG-I in Antiviral Response
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resolves10.1073/pnas.0407639101
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the <i>IFN</i> -β promoter
resolves10.1038/nature03124
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IFN Regulatory Factor 3-Dependent Induction of Type I IFNs by Intracellular Bacteria Is Mediated by a TLR- and Nod2-Independent Mechanism
resolves10.4049/jimmunol.174.3.1602
Immune Activation of Type I IFNs by <i>Listeria monocytogenes</i> Occurs Independently of TLR4, TLR2, and Receptor Interacting Protein 2 but Involves TANK-Binding Kinase 1
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CARD11 mediates factor‐specific activation of NF‐κB by the T cell receptor complex
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