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TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1
44/44 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
2 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 44 checked references that resolve
resolves10.1016/S1074-7613(02)00324-2
IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells
resolves10.1038/nri1648
New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
resolves10.1038/nature01355
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
resolves10.1172/JCI21404
IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6
resolves10.1016/j.immuni.2006.06.002
Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties
resolves10.1080/08830180212067
BENCH TO BEDSIDE: NEW APPROACHES TO THE IMMUNOTHERAPY OF UVEITIC DISEASE
resolves10.1016/S0002-9394(00)00659-0
Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel
resolves10.1073/pnas.96.13.7462
Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: A phase I/II clinical trial
resolves10.1189/jlb.0305130
Involvement of CCR5 in the passage of Th1-type cells across the blood-retina barrier in experimental autoimmune uveitis
resolves10.4049/jimmunol.161.1.122
Endogenous IL-12 Is Required for Induction and Expression of Experimental Autoimmune Uveitis
resolves10.1084/jem.189.2.219
Interleukin 12 Protects from a T Helper Type 1–mediated Autoimmune Disease, Experimental Autoimmune Uveitis, through a Mechanism Involving Interferon γ, Nitric Oxide, and Apoptosis
resolves10.4049/jimmunol.157.6.2668
Genetic susceptibility to experimental autoimmune uveoretinitis in the rat is associated with an elevated Th1 response
resolves10.4049/jimmunol.176.9.5652
STAT3 and NF-κB Signal Pathway Is Required for IL-23-Mediated IL-17 Production in Spontaneous Arthritis Animal Model IL-1 Receptor Antagonist-Deficient Mice
resolves10.4049/jimmunol.177.1.566
IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis
resolves10.4049/jimmunol.171.11.6173
Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice
resolves10.1073/pnas.1035999100
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
resolves10.4049/jimmunol.173.2.737
Cell Proliferation and STAT6 Pathways Are Negatively Regulated in T Cells by STAT1 and Suppressors of Cytokine Signaling
resolves10.4049/jimmunol.168.7.3181
Suppressors of Cytokine Signaling Proteins Are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance
resolves10.1038/ni1376
Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system
resolves10.1016/j.jneuroim.2005.07.021
Induction of suppressors of cytokine signaling (SOCS) in the retina during experimental autoimmune uveitis (EAU): Potential neuroprotective role of SOCS proteins
resolves10.4049/jimmunol.140.5.1490
A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens.
resolves10.1146/annurev.immunol.25.022106.141557
IL-17 Family Cytokines and the Expanding Diversity of Effector T Cell Lineages
resolves10.1038/ni1375
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells
resolves10.4049/jimmunol.177.8.5377
Two-Sided Roles of IL-27: Induction of Th1 Differentiation on Naive CD4+ T Cells versus Suppression of Proinflammatory Cytokine Production Including IL-23-Induced IL-17 on Activated CD4+ T Cells Partially Through STAT3-Dependent Mechanism
resolves10.4049/jimmunol.160.7.3513
IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages
resolves10.1111/j.0105-2896.2004.00211.x
Signaling by IL‐12 and IL‐23 and the immunoregulatory roles of STAT4
resolves10.1186/ar1227
resolves10.1073/pnas.0600666103
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
resolves10.1084/jem.20060522
Helper T cell differentiation enters a new era: Le Roi est mort; vive le Roi!
resolves10.1016/j.jns.2004.12.013
IL-27 subunits and its receptor (WSX-1) mRNAs are markedly up-regulated in inflammatory cells in the CNS during experimental autoimmune encephalomyelitis
resolves10.1016/j.brainres.2005.01.100
Production of IL-27 and other IL-12 family cytokines by microglia and their subpopulations
resolves10.1016/j.jneuroim.2003.08.040
Cytokines and chemokines in neuro-Behçet's disease compared to multiple sclerosis and other neurological diseases
resolves10.1007/s00347-003-0927-7
Augenbeteiligung bei Morbus Beh�et: Erste 5-Jahres-Ergebnisse zur Visusentwicklung nach Therapie mit Interferon alfa-2a
resolves10.1136/ard.62.5.492
Effects of interferon α treatment on the clinical course of refractory Behçet's disease: an open study
resolves10.1016/S0896-8411(03)00113-6
Humanized anti-interleukin-2 (IL-2) receptor alpha therapy: long-term results in uveitis patients and preliminary safety and activity data for establishing parameters for subcutaneous administration
resolves10.1016/j.jaut.2004.11.006
SOCS5 mRNA levels in peripheral blood mononuclear cells (PBMC): a potential bio-marker for monitoring response of uveitis patients to Daclizumab therapy
The 2 references without a DOI — listed, not checked
no DOI — not checkedBecker, M.D., Garman, K., Whitcup, S.M., Planck, S.R. & Rosenbaum, J.T. Inhibition of leukocyte sticking and infiltration, but not rolling, by antibodies to ICAM-1 and LFA-1 in murine endotoxin-induced uveitis. Invest. Ophthalmol. Vis. Sci. 42, 2563–2566 (2001).
no DOI — not checkedNussenblatt, R.B. Proctor lecture. Experimental autoimmune uveitis: mechanisms of disease and clinical therapeutic indications. Invest. Ophthalmol. Vis. Sci. 32, 3131–3141 (1991).
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