Reference health

Effort but not Reward Sensitivity is Altered by Acute Sickness Induced by Experimental Endotoxemia in Humans

https://doi.org/10.1038/npp.2017.231
CiteStamped reference-health badge
72/72 checkable references clean · checked 2026-07-22

Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.

5 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.

The 72 checked references that resolve
resolves10.1016/j.yfrne.2014.05.004
Sex differences in anxiety and depression clinical perspectives
resolves10.4161/viru.26982
Gender differences in sepsis
resolves10.1038/srep16880
The role of cognitive effort in subjective reward devaluation and risky decision-making
resolves10.1002/cpt.618
What Makes You Feel Sick After Inflammation? Predictors of Acute and Persisting Physical Sickness Symptoms Induced by Experimental Endotoxemia
resolves10.1016/j.coph.2008.12.014
Dissecting components of reward: ‘liking’, ‘wanting’, and learning
resolves10.1016/j.amjmed.2005.07.047
Does Methylphenidate Reduce the Symptoms of Chronic Fatigue Syndrome?
resolves10.1016/S0165-1781(01)00315-8
Immunotherapy with interferon-alpha in patients affected by chronic hepatitis C induces an intercorrelated stimulation of the cytokine network and an increase in depressive and anxiety symptoms
resolves10.1371/journal.pone.0140678
Suppression of Locomotor Activity in Female C57Bl/6J Mice Treated with Interleukin-1β: Investigating a Method for the Study of Fatigue in Laboratory Animals
resolves10.1016/j.bbi.2012.06.011
Inflammation and cancer-related fatigue: Mechanisms, contributing factors, and treatment implications
resolves10.1001/archgenpsychiatry.2011.2094
Dopaminergic Mechanisms of Reduced Basal Ganglia Responses to Hedonic Reward During Interferon Alfa Administration
resolves10.1016/j.cortex.2015.04.003
Dopamine enhances willingness to exert effort for reward in Parkinson's disease
resolves10.1006/brbi.2000.0613
Cytokine-Induced Sickness Behavior: Where Do We Stand?
resolves10.1016/j.tins.2013.10.003
The neuroimmune basis of fatigue
resolves10.1016/j.biopsych.2015.05.015
Acute Changes in Striatal Microstructure Predict the Development of Interferon-Alpha Induced Fatigue
resolves10.1016/j.biopsych.2009.09.033
A Meta-Analysis of Cytokines in Major Depression
resolves10.1016/j.biopsych.2010.06.010
Inflammation-Induced Anhedonia: Endotoxin Reduces Ventral Striatum Responses to Reward
resolves10.1016/j.bbi.2015.08.013
Men and women differ in inflammatory and neuroendocrine responses to endotoxin but not in the severity of sickness symptoms
resolves10.1038/mp.2016.264
Selective increase of cerebrospinal fluid IL-6 during experimental systemic inflammation in humans: association with depressive symptoms
resolves10.1093/ijnp/pyu084
Levodopa Reverses Cytokine-Induced Reductions in Striatal Dopamine Release
resolves10.1016/j.yfrne.2012.09.003
Cytokine effects on the basal ganglia and dopamine function: The subcortical source of inflammatory malaise
resolves10.1038/npp.2016.143
Inflammation Effects on Motivation and Motor Activity: Role of Dopamine
resolves10.1016/j.schres.2015.07.023
Effort-based decision making as an objective paradigm for the assessment of motivational deficits in schizophrenia
resolves10.1038/sj.npp.1300217
Elevated Interleukin-6 in the Cerebrospinal Fluid of a Previously Delineated Schizophrenia Subtype
resolves10.1016/S0166-4115(08)62386-9
Development of NASA-TLX (Task Load Index): Results of Empirical and Theoretical Research
resolves10.1016/j.jpainsymman.2011.03.026
Effects of Methylphenidate on Fatigue and Depression: A Randomized, Double-Blind, Placebo-Controlled Trial
resolves10.1016/j.jns.2011.05.036
Neuroanatomical correlates of depression and apathy in Parkinson's disease: Magnetic resonance imaging studies
resolves10.1016/j.bbi.2014.11.014
Modality and sex differences in pain sensitivity during human endotoxemia
resolves10.3389/fimmu.2017.00021
Role of Inflammation in Human Fatigue: Relevance of Multidimensional Assessments and Potential Neuronal Mechanisms
resolves10.1523/JNEUROSCI.0292-16.2016
Neural Signatures of Value Comparison in Human Cingulate Cortex during Decisions Requiring an Effort-Reward Trade-off
resolves10.1176/appi.ajp.157.5.683
Cytokines and the Brain: Implications for Clinical Psychiatry
resolves10.1186/s13075-015-0667-5
Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: a randomized controlled study
resolves10.1016/j.pbb.2006.06.004
Lipopolysaccharide and interleukin-1β decrease sucrose intake but do not affect expression of place preference in rats
resolves10.1006/brbi.2001.0634
Effects of Interleukin-1β on Food-Maintained Behavior in the Mouse
resolves10.1038/npp.2016.191
Lipopolysaccharide Alters Motivated Behavior in a Monetary Reward Task: a Randomized Trial
resolves10.1016/j.jad.2011.12.049
Can bipolar disorder be viewed as a multi-system inflammatory disease?
resolves10.1164/rccm.201204-0645OC
Reversal of Immunoparalysis in Humans <i>In Vivo</i> : A Double-Blind, Placebo-controlled, Randomized Pilot Study
resolves10.1016/j.bbi.2007.12.009
IFN-alpha-induced motor slowing is associated with increased depression and fatigue in patients with chronic hepatitis C
resolves10.1002/mds.21656
Methylphenidate improves fatigue scores in Parkinson disease: A randomized controlled trial
resolves10.1016/j.biopsych.2008.11.029
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
resolves10.1038/nri.2015.5
The role of inflammation in depression: from evolutionary imperative to modern treatment target
resolves10.1037/0021-843X.110.1.40
Misunderstanding analysis of covariance.
resolves10.1038/npp.2015.17
Sex Differences in Depressive and Socioemotional Responses to an Inflammatory Challenge: Implications for Sex Differences in Depression
resolves10.1016/j.jpainsymman.2010.06.020
Psychostimulants for the Management of Cancer-Related Fatigue: A Systematic Review and Meta-Analysis
resolves10.1038/sj.mp.4002006
The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression
resolves10.2174/138920008785821738
Chronic Immune Stimulation Correlates with Reduced Phenylalanine Turnover
resolves10.1007/s00213-013-3285-4
Effort-related motivational effects of the pro-inflammatory cytokine interleukin 1-beta: studies with the concurrent fixed ratio 5/ chow feeding choice task
resolves10.1007/s00296-004-0463-z
The effect of interleukin-1 blockade on fatigue in rheumatoid arthritis—a pilot study
resolves10.1016/j.biopsych.2007.09.024
Inflammatory Cytokine Alterations in Schizophrenia: A Systematic Quantitative Review
resolves10.1371/journal.pone.0047934
Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences
resolves10.1038/mp.2009.47
Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients
resolves10.1016/j.neuroscience.2015.05.018
The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders
resolves10.1186/s12974-017-0796-7
Interleukin-1 as a mediator of fatigue in disease: a narrative review
resolves10.7326/M16-2391
Cytokine Inhibition in Patients With Chronic Fatigue Syndrome
resolves10.1016/j.pnpbp.2014.01.013
Inflamed moods: A review of the interactions between inflammation and mood disorders
resolves10.1016/0166-4328(94)90108-2
Anhedonia or anergia? Effects of haloperidol and nucleus accumbens dopamine depletion on instrumental response selection in a T-maze cost/benefit procedure
resolves10.1093/brain/aww050
Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology
resolves10.1016/j.bbi.2006.11.004
The association between fatigue and inflammatory marker levels in cancer patients: A quantitative review
resolves10.1111/jnp.12013
Impulsivity and apathy in Parkinson's disease
resolves10.1523/JNEUROSCI.2081-16.2017
A Selective Role for Dopamine in Learning to Maximize Reward But Not to Minimize Effort: Evidence from Patients with Parkinson's Disease
resolves10.1523/JNEUROSCI.1350-14.2014
Learning To Minimize Efforts versus Maximizing Rewards: Computational Principles and Neural Correlates
resolves10.1016/j.bbi.2013.12.022
The role of IL-1β and TNF-α signaling in the genesis of cancer treatment related symptoms (CTRS): A study using cytokine receptor-deficient mice
resolves10.1016/j.psc.2013.10.002
Apathy Following Traumatic Brain Injury
resolves10.1097/YCO.0b013e32835aa4b4
Is bipolar disorder an inflammatory condition? The relevance of microglial activation
resolves10.1016/j.neubiorev.2016.02.017
Mapping inflammation onto mood: Inflammatory mediators of anhedonia
resolves10.1097/00005053-199808000-00004
Negative, Positive, and Disorganized Symptom Dimensions in Schizophrenia, Major Depression, and Bipolar Disorder
resolves10.1038/npp.2014.141
Lipopolysaccharide Reduces Incentive Motivation While Boosting Preference for High Reward in Mice
resolves10.1523/JNEUROSCI.4387-11.2011
Amping Up Effort: Effects of<i>d</i>-Amphetamine on Human Effort-Based Decision-Making
resolves10.1017/S0033291704003526
Early increase in vegetative symptoms predicts IFN-α-induced cognitive-depressive changes
resolves10.1097/SPC.0b013e32835dabe3
Inflammation and neural signaling
resolves10.1007/s00213-016-4392-9
Effort-related motivational effects of the pro-inflammatory cytokine interleukin-6: pharmacological and neurochemical characterization
resolves10.1016/j.jad.2014.07.032
A review of the relationship between proinflammatory cytokines and major depressive disorder
resolves10.1016/j.biopsych.2010.06.016
Magnetic Resonance Spectroscopy Studies of Glutamate-Related Abnormalities in Mood Disorders
The 5 references without a DOI — listed, not checked
no DOI — not checkedBonnelle V, Manohar S, Behrens T, Husain M (2016). Individual differences in premotor brain systems underlie behavioral apathy. Cereb Cortex 26: 807–819.
no DOI — not checkedBonnelle V, Veromann KR, Burnett Heyes S, Lo Sterzo E, Manohar S, Husain M (2015). Characterization of reward and effort mechanisms in apathy. J Physiol 109: 16–26.
no DOI — not checkedDembic Z The Cytokines of the Immune System: The Role of Cytokines in Disease Related to Immune Response. Academic Press: Amsterdam; (2015).
no DOI — not checkedHarrison NA, Voon V, Cercignani M, Cooper EA, Pessiglione M, Critchley HD (2015). Archival report a neurocomputational account of how inflammation enhances sensitivity to punishments versus rewards. Biol Psychiatry 80: 1–9.
no DOI — not checkedMcNair DM, Lorr M, Droppleman LF (1971) The Profile of Mood States. Educational and Industrial Testing Service: San Diego, CA, USA.
What this badge says. CiteStamped means the CHECKABLE references of this work were clean at the dated check: each resolved to a known work in a public registry, and none carried a retraction notice at that time. It says nothing about the quality, findings, or importance of the work itself, and nothing about references deposited without a DOI.

checked 2026-07-22 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record

Embed this badge

Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.

<a href="https://citestamp.com/citestamped/10.1038/npp.2017.231"><img src="https://citestamp.com/citestamped/10.1038/npp.2017.231/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[![CiteStamped reference-health badge](https://citestamp.com/citestamped/10.1038/npp.2017.231/badge.svg)](https://citestamp.com/citestamped/10.1038/npp.2017.231)