Reference health
Platforms for antibiotic discovery
1 of 116 checkable references need attention · checked 2026-08-03
At the dated check, the references listed below either did not resolve in Crossref or DataCite, or carried a retraction notice. Each one is shown with the registry record that put it there.
8 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
References needing attention
marked retracted — notice via Crossref, record curated by Retraction Watch10.1073/pnas.1100186108
RETRACTED: Bacterial persistence by RNA endonucleases
The 115 checked references that resolve
resolves10.3181/00379727-55-14461
Streptomycin, a Substance Exhibiting Antibiotic Activity Against Gram-Positive and Gram-Negative Bacteria.*
resolves10.1128/AAC.30.4.532
In vitro and in vivo activity of LY 146032, a new cyclic lipopeptide antibiotic
resolves10.1007/BF01975171
Susceptibility of anaerobic bacteria to the new streptogramin RP 59500 in vitro
resolves10.1128/AAC.46.2.267-274.2002
Evolution of Drug Resistance in
<i>Mycobacterium tuberculosis</i>
: Clinical and Molecular Perspective
resolves10.1093/jac/dkr173
Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs
resolves10.1126/science.8284673
<i>inhA</i>
, a Gene Encoding a Target for Isoniazid and Ethionamide in
<i>Mycobacterium tuberculosis</i>
resolves10.1128/AAC.47.12.3799-3805.2003
<i>ethA</i>
,
<i>inhA</i>
, and
<i>katG</i>
Loci of Ethionamide-Resistant Clinical
<i>Mycobacterium tuberculosis</i>
Isolates
resolves10.1126/science.1208813
Pyrazinamide Inhibits Trans-Translation in
<i>Mycobacterium tuberculosis</i>
resolves10.1126/science.1106753
A Diarylquinoline Drug Active on the ATP Synthase of
<i>Mycobacterium tuberculosis</i>
resolves10.1128/AAC.33.9.1493
Inhibition of synthesis of arabinogalactan by ethambutol in Mycobacterium smegmatis
resolves10.1371/journal.pone.0009085
Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults
resolves10.1111/j.1365-2982.2010.01620.x
Reduced anxiety-like behavior and central neurochemical change in germ-free mice
resolves10.1073/pnas.1000087107
Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation
resolves10.4161/bact.19274
Phage-based platforms for the clinical detection of human bacterial pathogens
resolves10.1021/jm9904598
Inhibitors of Efflux Pumps in <i>Pseudomonas </i><i>a</i><i>eruginosa</i> Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin
resolves10.1128/AAC.45.1.105-116.2001
Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in
<i>Pseudomonas aeruginosa</i>
: Novel Agents for Combination Therapy
resolves10.1126/science.1083137
Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump
resolves10.1073/pnas.0900693106
The assembled structure of a complete tripartite bacterial multidrug efflux pump
resolves10.1038/nature10641
Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
resolves10.1016/S0169-409X(00)00129-0
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
resolves10.1073/pnas.95.12.6602
Bacteria lacking a multidrug pump: A sensitive tool for drug discovery
resolves10.1073/pnas.030540597
Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5′-methoxyhydnocarpin, a multidrug pump inhibitor
resolves10.1021/jm700967e
Physicochemical Properties of Antibacterial Compounds: Implications for Drug Discovery
resolves10.1517/17460441.3.5.487
Are natural products still the best source for antibacterial discovery? The bacterial entry factor
resolves10.1126/science.1142189
An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site
resolves10.1073/pnas.0604055103
Identification of novel antimicrobials using a live-animal infection model
resolves10.1128/AAC.48.8.2838-2844.2004
Prediction of Mechanisms of Action of Antibacterial Compounds by Gene Expression Profiling
resolves10.1038/nature04784
Platensimycin is a selective FabF inhibitor with potent antibiotic properties
resolves10.1093/dnares/dsi012
Complete set of ORF clones of Escherichia coli ASKA library (A Complete Set of E. coli K-12 ORF Archive): Unique Resources for Biological Research
resolves10.7164/antibiotics.48.67
Effect of Polymyxin B Nonapeptide on Daptomycin Permeability and Cell Surface Properties in Pseudomonas aeruginosa, Escherichia coli, and Pasteurella multocida.
resolves10.1021/ol050901i
Sporolides A and B: Structurally Unprecedented Halogenated Macrolides from the Marine Actinomycete
<i>Salinispora</i>
<i>t</i>
<i>ropica</i>
resolves10.1038/417141a
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
resolves10.1038/nbt820
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
resolves10.1038/nbt784
A genomics-guided approach for discovering and expressing cryptic metabolic pathways
resolves10.1046/j.1365-2958.1999.01579.x
The A‐factor regulatory cascade leading to streptomycin biosynthesis in <i>Streptomyces griseus</i> : identification of a target gene of the A‐factor receptor
resolves10.1007/s10295-010-0730-9
Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters
resolves10.1111/j.1751-7915.2010.00219.x
Engineering
<i>Streptomyces coelicolor</i>
for heterologous expression of secondary metabolite gene clusters
resolves10.1073/pnas.0914833107
Genome-minimized
<i>Streptomyces</i>
host for the heterologous expression of secondary metabolism
resolves10.1128/jb.179.23.7360-7368.1997
A study of iterative type II polyketide synthases, using bacterial genes cloned from soil DNA: a means to access and use genes from uncultured microorganisms
resolves10.1128/AEM.68.9.4301-4306.2002
Isolation of Antibiotics Turbomycin A and B from a Metagenomic Library of Soil Microbial DNA
resolves10.1126/science.1070633
Isolating "Uncultivable" Microorganisms in Pure Culture in a Simulated Natural Environment
resolves10.1128/AEM.01754-09
Use of Ichip for High-Throughput
<i>In Situ</i>
Cultivation of “Uncultivable” Microbial Species
resolves10.1016/j.chembiol.2010.02.010
Siderophores from Neighboring Organisms Promote the Growth of Uncultured Bacteria
resolves10.1128/AEM.01309-07
Incubation of Environmental Samples in a Diffusion Chamber Increases the Diversity of Recovered Isolates
resolves10.1128/AAC.38.12.2750
Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis
resolves10.1073/pnas.77.7.3957
Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.
resolves10.7164/antibiotics.28.721
Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle.
resolves10.1007/s10637-010-9493-4
A Phase II trial of 17-allylamino, 17-demethoxygeldanamycin (17-AAG, tanespimycin) in patients with metastatic melanoma
resolves10.1073/pnas.73.12.4474
Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.
resolves10.1126/science.1184785
That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda
resolves10.1126/science.1190719
Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome
resolves10.1086/595011
Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
resolves10.1371/journal.pbio.1000317
Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli
resolves10.1128/JB.186.24.8172-8180.2004
Specialized Persister Cells and the Mechanism of Multidrug Tolerance in
<i>Escherichia coli</i>
resolves10.1126/science.1163806
Molecular Mechanisms of HipA-Mediated Multidrug Tolerance and Its Neutralization by HipB
resolves10.1128/AAC.00144-08
Role of Global Regulators and Nucleotide Metabolism in Antibiotic Tolerance in
<i>Escherichia coli</i>
resolves10.1128/AAC.00860-09
Patients with Long-Term Oral Carriage Harbor High-Persister Mutants of
<i>Candida albicans</i>
resolves10.1128/JB.01651-09
Emergence of
<i>Pseudomonas aeruginosa</i>
Strains Producing High Levels of Persister Cells in Patients with Cystic Fibrosis
resolves10.7164/antibiotics.29.668
Naturally-occurring .BETA.-lactamase inhibitors with antibacterial activity.
resolves10.1016/j.tim.2006.07.008
The β-lactamase threat in Enterobacteriaceae, Pseudomonas and Acinetobacter
resolves10.1016/j.ijantimicag.2007.08.003
Metallo-β-lactamase IMP-18 is located in a class 1 integron (In96) in a clinical isolate of Pseudomonas aeruginosa from Mexico
resolves10.1128/AAC.00568-10
Mechanistic Studies of the Inactivation of TEM-1 and P99 by NXL104, a Novel Non-β-Lactam β-Lactamase Inhibitor
resolves10.1093/jac/dkf043
Molecular characterization of metallo-b-lactamase-producing Acinetobacter baumannii and Acinetobacter genomospecies 3 from Korea: identification of two new integrons carrying the blaVIM-2 gene cassettes
resolves10.1016/S1473-3099(10)70143-2
Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study
resolves10.1021/ci049714+
ZINC − A Free Database of Commercially Available Compounds for Virtual Screening
resolves10.1002/(SICI)1098-1128(199601)16:1<3::AID-MED1>3.0.CO;2-6
The art and practice of structure-based drug design: A molecular modeling perspective
resolves10.1016/S1473-3099(12)70293-1
A comprehensive regulatory framework to address the unmet need for new antibacterial treatments
resolves10.1056/NEJMoa0907635
Treatment with Monoclonal Antibodies against
<i>Clostridium difficile</i>
Toxins
resolves10.1126/science.1116739
Small-Molecule Inhibitor of
<i>Vibrio cholerae</i>
Virulence and Intestinal Colonization
resolves10.1016/j.bbrc.2010.04.113
Therapeutic effect of (Z)-3-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl) acrylonitrile (DMMA) against Staphylococcus aureus infection in a murine model
resolves10.1146/annurev.micro.52.1.41
LANTIBIOTICS: Biosynthesis and Biological Activities of Uniquely Modified Peptides from Gram-Positive Bacteria
resolves10.1007/s00284-010-9710-6
In Vitro Management of Hospital Pseudomonas aeruginosa Biofilm Using Indigenous T7-Like Lytic Phage
resolves10.1099/00221287-144-11-3039
Biofilm susceptibility to bacteriophage attack: the role of phage-borne polysaccharide depolymerase
resolves10.1111/j.1749-4486.2009.01973.x
A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic‐resistant <i>Pseudomonas aeruginosa</i>; a preliminary report of efficacy
The 8 references without a DOI — listed, not checked
no DOI — not checkedFleming, A. G. Responsibilities and opportunities of the private practitioner in preventive medicine. Can. Med. Assoc. J. 20, 11–13 (1929).
no DOI — not checkedMcDonald, K. M. et al. Closing the quality gap: a critical analysis of quality improvement strategies. (Vol. 7: Care Coordination; Technical Review No. 9) US Agency for Healthcare Research and Quality [online] , (2007).
no DOI — not checkedLewis, K. in Antibiotic resistance: implications for global health and novel intervention strategies — workshop summary (eds Choffnes, E. R., Relman, D. A. & Mack, A.) 202–223 (National Academies Press, 2010).
no DOI — not checkedBaltz, R. H. Antibiotics from actinomycetes: will a renaissance follow the decline and fall? SIM News 55, 186–196 (2005).
no DOI — not checkedKhokhlov, A. S. et al. The A-factor, responsible for streptomycin biosynthesis by mutant strains of Actinomyces streptomycini. Dokl. Akad. Nauk SSSR 177, 232–235 (1967).
no DOI — not checkedHorinouchi, S. A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus. Front. Biosci. 7, 2045–2057 (2002).
no DOI — not checkedSlonczewski, J. & Foster, J. W. Microbiology: An Evolving Science 2nd edn (W.W. Norton, 2011).
no DOI — not checkedIrwin, J. J. Using ZINC to acquire a virtual screening library. Curr. Protoc. Bioinformatics Ch. 14, Unit 14.6 (2008).
What this badge says. CiteStamped means the CHECKABLE references of this
work were clean at the dated check: each resolved to a known work in a public registry, and none
carried a retraction notice at that time. It says nothing about the quality, findings,
or importance of the work itself, and nothing about references deposited without a DOI.
checked 2026-08-03 — re-checked daily as this page is visited; titles and statuses come from Crossref and DataCite and are not part of the signed record
Embed this badge
Both snippets point at the live badge image and link back to this page. The badge re-renders from the daily check, so an embed never goes stale by more than a day of visits.
<a href="https://citestamp.com/citestamped/10.1038/nrd3975"><img src="https://citestamp.com/citestamped/10.1038/nrd3975/badge.svg" alt="CiteStamped reference-health badge" width="460" height="64"></a>
[](https://citestamp.com/citestamped/10.1038/nrd3975)