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Post-transcriptional regulation of gene expression in innate immunity
135/135 checkable references clean · checked 2026-07-26
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
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The 135 checked references that resolve
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Pattern Recognition Receptors and the Innate Immune Response to Viral Infection
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Genome-Wide Analysis of Alternative Splicing during Dendritic Cell Response to a Bacterial Challenge
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Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites
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Pre-mRNA Processing Reaches Back toTranscription and Ahead to Translation
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Kinetics of Toll-like receptor-4 splice variants expression in lipopolysaccharide-stimulated antigen presenting cells of healthy donors and patients with cystic fibrosis
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Cutting Edge: Naturally Occurring Soluble Form of Mouse Toll-Like Receptor 4 Inhibits Lipopolysaccharide Signaling
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Use of Transcriptome Data to Unravel the Fine Structure of Genes Involved in Sepsis
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<i>Myobacterium tuberculosis</i>
Induces Selective Up-Regulation of TLRs in the Mononuclear Leukocytes of Patients with Active Pulmonary Tuberculosis
resolves10.4049/jimmunol.168.11.5629
Transcriptional Regulation of the Human
<i>Toll-Like Receptor 2</i>
Gene in Monocytes and Macrophages
resolves10.1016/j.bbrc.2004.08.203
Identification of a novel isoform of MD-2 that downregulates lipopolysaccharide signaling
resolves10.4049/jimmunol.0903543
Identification of a Novel Human MD-2 Splice Variant That Negatively Regulates Lipopolysaccharide-Induced TLR4 Signaling
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Inhibition of Interleukin 1 Receptor/Toll-like Receptor Signaling through the Alternatively Spliced, Short Form of MyD88 Is Due to Its Failure to Recruit IRAK-4
resolves10.1016/S0960-9822(02)00712-1
Regulation of Interleukin-1- and Lipopolysaccharide-Induced NF-κB Activation by Alternative Splicing of MyD88
resolves10.1016/S0014-5793(03)00747-6
MyD88<sub>S</sub>, a splice variant of MyD88, differentially modulates NF‐κB‐ and AP‐1‐dependent gene expression
resolves10.1074/jbc.M103815200
IRAK1b, a Novel Alternative Splice Variant of Interleukin-1 Receptor-associated Kinase (IRAK), Mediates Interleukin-1 Signaling and Has Prolonged Stability
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A novel splice variant of mouse interleukin-1-receptor-associated kinase-1 (IRAK-1) activates nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (JNK)
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A Novel Splice Variant of Interleukin-1 Receptor (IL-1R)-Associated Kinase 1 Plays a Negative Regulatory Role in Toll/IL-1R-Induced Inflammatory Signaling
resolves10.1074/jbc.M403068200
The Murine Irak2 Gene Encodes Four Alternatively Spliced Isoforms, Two of Which Are Inhibitory
resolves10.1074/jbc.M109.072231
Analysis of a TIR-less Splice Variant of TRIF Reveals an Unexpected Mechanism of TLR3-mediated Signaling
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TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway
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Functional Characterization of Interferon Regulatory Factor 3a (IRF-3a), an Alternative Splice Isoform of IRF-3
resolves10.1038/cmi.2010.55
Interferon regulatory factor 3-CL, an isoform of IRF3, antagonizes activity of IRF3
resolves10.1016/j.bbagrm.2011.01.006
Identification of novel alternative splicing variants of interferon regulatory factor 3
resolves10.1074/jbc.M508848200
Elevated Levels of the 64-kDa Cleavage Stimulatory Factor (CstF-64) in Lipopolysaccharide-stimulated Macrophages Influence Gene Expression and Induce Alternative Poly(A) Site Selection
resolves10.1016/j.cell.2012.05.043
Transcript Dynamics of Proinflammatory Genes Revealed by Sequence Analysis of Subcellular RNA Fractions
resolves10.1073/pnas.1309990110
RNA splicing regulates the temporal order of TNF-induced gene expression
resolves10.1038/nbt.1861
Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells
resolves10.1073/pnas.1219192110
Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response
resolves10.1186/1471-2164-11-259
Major role for mRNA stability in shaping the kinetics of gene induction
resolves10.1038/ni.1699
The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules
resolves10.1073/pnas.83.6.1670
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.
resolves10.1016/0092-8674(86)90341-7
A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
resolves10.1093/nar/gkm959
ARED Organism: expansion of ARED reveals AU-rich element cluster variations between human and mouse
resolves10.1016/S1074-7613(00)80038-2
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements
resolves10.1016/j.bbrc.2006.05.093
Differential regulation of ARE-mediated TNFα and IL-1β mRNA stability by lipopolysaccharide in RAW264.7 cells
resolves10.1038/sj.emboj.7600163
MK2‐induced tristetraprolin:14‐3‐3 complexes prevent stress granule association and ARE‐mRNA decay
resolves10.1074/jbc.M607347200
Tristetraprolin (TTP)-14-3-3 Complex Formation Protects TTP from Dephosphorylation by Protein Phosphatase 2a and Stabilizes Tumor Necrosis Factor-α mRNA
resolves10.1101/gad.1467606
Endotoxic shock in
<i>AUF1</i>
knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs
resolves10.1016/S1074-7613(00)80411-2
A Pathogenetic Role for TNFα in the Syndrome of Cachexia, Arthritis, and Autoimmunity Resulting from Tristetraprolin (TTP) Deficiency
resolves10.1182/blood.V95.6.1891
Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability
resolves10.1172/JCI45021
Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis
resolves10.1128/MCB.23.10.3506-3515.2003
A Constitutive Decay Element Promotes Tumor Necrosis Factor Alpha mRNA Degradation via an AU-Rich Element-Independent Pathway
resolves10.1074/jbc.M603915200
The Polypyrimidine Tract-binding Protein (PTB) Is Involved in the Post-transcriptional Regulation of Human Inducible Nitric Oxide Synthase Expression
resolves10.1038/nsmb.2296
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC
resolves10.1101/gad.468808
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
resolves10.1083/jcb.200707166
Regulation of translation is required for dendritic cell function and survival during activation
resolves10.1038/ncb1996
Adaptive suppression of the ATF4–CHOP branch of the unfolded protein response by toll-like receptor signalling
resolves10.1038/ncb2408
Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B
resolves10.1073/pnas.1005320107
eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
resolves10.1006/viro.1996.0143
Phosphorylation State of the Cap-Binding Protein eIF4E during Viral Infection
resolves10.1038/ni.2291
Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E
resolves10.1074/jbc.M807822200
Interleukin-1 Receptor-associated Kinase 2 Is Critical for Lipopolysaccharide-mediated Post-transcriptional Control
resolves10.1038/emboj.2013.2
IRAK‐M mediates Toll‐like receptor/IL‐1R‐induced NFκB activation and cytokine production
resolves10.1038/sj.emboj.7601920
Anti‐inflammatory lipid mediator 15d‐PGJ2 inhibits translation through inactivation of eIF4A
resolves10.1002/eji.200838761
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells
resolves10.1091/mbc.e12-02-0135
Cot/tpl2-MKK1/2-Erk1/2 controls mTORC1-mediated mRNA translation in Toll-like receptor–activated macrophages
resolves10.1093/emboj/16.12.3693
Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k
resolves10.1016/j.chom.2011.03.008
Leishmania Repression of Host Translation through mTOR Cleavage Is Required for Parasite Survival and Infection
resolves10.1016/j.immuni.2008.08.012
The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response
resolves10.1038/ni.2740
Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR
resolves10.1038/nrm2838
The mechanism of eukaryotic translation initiation and principles of its regulation
resolves10.1074/jbc.272.34.21120
The Role of 3′ Poly(A) Tail Metabolism in Tumor Necrosis Factor-α Regulation
resolves10.1016/S1074-7613(02)00456-9
RANTES Production by Memory Phenotype T Cells Is Controlled by a Posttranscriptional, TCR-Dependent Process
resolves10.1128/MCB.05133-11
CPEB Control of NF-κB Nuclear Localization and Interleukin-6 Production Mediates Cellular Senescence
resolves10.1093/nar/15.20.8125
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs
resolves10.1073/pnas.0802301105
Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells
resolves10.1073/pnas.0810916106
Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
resolves10.1016/j.cell.2014.01.021
A Bicistronic MAVS Transcript Highlights a Class of Truncated Variants in Antiviral Immunity
resolves10.1091/mbc.02-02-0017
Hypoxia-inducible Factor-1α mRNA Contains an Internal Ribosome Entry Site That Allows Efficient Translation during Normoxia and Hypoxia
resolves10.1152/ajplung.90508.2008
Cap-independent translation of human SP-A 5′-UTR variants: a double-loop structure and<i>cis</i>-element contribution
resolves10.1261/rna.033019.112
IRES-dependent translation of egr2 is induced under inflammatory conditions
resolves10.1371/journal.pone.0085314
Inflammatory Conditions Induce IRES-Dependent Translation of cyp24a1
resolves10.1093/nar/gkt956
An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins
resolves10.1371/journal.pgen.1002977
The p38/MK2-Driven Exchange between Tristetraprolin and HuR Regulates AU–Rich Element–Dependent Translation
resolves10.1128/MCB.05340-11
AU-Rich-Element-Dependent Translation Repression Requires the Cooperation of Tristetraprolin and RCK/P54
resolves10.1093/emboj/19.15.4154
TIA‐1 is a translational silencer that selectively regulates the expression of TNF‐α
resolves10.1379/1466-1268(2002)007<0213:VSTROE>2.0.CO;2
&cestchinlong;Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation
resolves10.1128/MCB.19.10.6898
Delayed Translational Silencing of Ceruloplasmin Transcript in Gamma Interferon-Activated U937 Monocytic Cells: Role of the 3′ Untranslated Region
resolves10.1128/MCB.23.5.1509-1519.2003
Transcript-Selective Translational Silencing by Gamma Interferon Is Directed by a Novel Structural Element in the Ceruloplasmin mRNA 3′ Untranslated Region
resolves10.1016/S0092-8674(03)00773-6
Regulated Release of L13a from the 60S Ribosomal Subunit as A Mechanism of Transcript-Specific Translational Control
resolves10.1016/j.molcel.2006.11.028
L13a Blocks 48S Assembly: Role of a General Initiation Factor in mRNA-Specific Translational Control
resolves10.1128/MCB.00824-08
Genome-Wide Polysome Profiling Reveals an Inflammation-Responsive Posttranscriptional Operon in Gamma Interferon-Activated Monocytes
resolves10.1016/j.molcel.2008.09.019
DAPK-ZIPK-L13a Axis Constitutes a Negative-Feedback Module Regulating Inflammatory Gene Expression
resolves10.1038/sj.emboj.7601774
A post‐transcriptional pathway represses monocyte VEGF‐A expression and angiogenic activity
resolves10.1371/journal.pbio.1001635
The HILDA Complex Coordinates a Conditional Switch in the 3′-Untranslated Region of the VEGFA mRNA
resolves10.1172/JCI65124
Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis
resolves10.1002/j.1460-2075.1988.tb02862.x
The structure and expression of a novel gene activated in early mouse embryogenesis.
resolves10.1038/nature07672
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
resolves10.1038/nbt.1633
Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs
resolves10.1038/nature05874
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
resolves10.1128/mBio.00206-10
Unique Signatures of Long Noncoding RNA Expression in Response to Virus Infection and Altered Innate Immune Signaling
resolves10.1093/nar/gks1076
miRNA repression of translation in vitro takes place during 43S ribosomal scanning
resolves10.1016/j.cell.2013.01.015
The NeST Long ncRNA Controls Microbial Susceptibility and Epigenetic Activation of the Interferon-γ Locus
resolves10.4049/jimmunol.1200774
Cutting Edge: Influence of <i>Tmevpg1</i>, a Long Intergenic Noncoding RNA, on the Expression of <i>Ifng</i> by Th1 Cells
resolves10.1126/science.1240925
A Long Noncoding RNA Mediates Both Activation and Repression of Immune Response Genes
resolves10.7554/eLife.00762
A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics
resolves10.1073/pnas.1313768111
The long noncoding RNA
<i>THRIL</i>
regulates TNFα expression through its interaction with hnRNPL
resolves10.1038/nm1784
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase
The 1 reference without a DOI — listed, not checked
no DOI — not checkedBrannan, C. I., Dees, E. C., Ingram, R. S. & Tilghman, S. M. The product of the H19 gene may function as an RNA. Mol. Cell. Biol. 10, 28–36 (1990).
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