At the dated check, the references listed below either did not resolve in
Crossref or DataCite, or carried a retraction notice. Each one is shown with the
registry record that put it there.
The 205 checked references that resolve
resolves10.1038/nrm3270The unfolded protein response: controlling cell fate decisions under ER stress and beyond
resolves10.1016/j.celrep.2013.03.024Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments
resolves10.1126/science.1081208BAX and BAK Regulation of Endoplasmic Reticulum Ca
<sup>2+</sup>
: A Control Point for Apoptosis
resolves10.1038/ncb0311-184Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
resolves10.1038/ncb2738ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
resolves10.1038/nrn1007Unfolding the role of protein misfolding in neurodegenerative diseases
resolves10.1038/nrm2101Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
resolves10.1101/cshperspect.a004507Chemical and Biological Approaches for Adapting Proteostasis to Ameliorate Protein Misfolding and Aggregation Diseases-Progress and Prognosis
resolves10.2174/156652411794474419Converging Pathways in the Occurrence of Endoplasmic Reticulum (ER) Stress in Huntingtons Disease
resolves10.1126/science.1245296Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient–Derived Neurons
resolves10.1371/journal.pone.0047950ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson’s Disease
resolves10.1074/jbc.M110.156430The Endoplasmic Reticulum Stress Sensor, ATF6α, Protects against Neurotoxin-induced Dopaminergic Neuronal Death
resolves10.1038/mt.2012.28Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease
resolves10.1111/j.1471-4159.2005.03428.xCHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an <i>in vivo</i> neurotoxin model of parkinsonism
resolves10.1038/nn.2297A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice
resolves10.1093/hmg/ddq546The unfolded protein response in familial amyotrophic lateral sclerosis
resolves10.1371/journal.pone.0066672Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis
resolves10.1038/sj.cdd.4402166The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis
resolves10.1073/pnas.0707906105Deletion of the BH3-only protein
<i>puma</i>
protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice
resolves10.1101/gad.1640108ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
resolves10.1101/gad.1830709XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
resolves10.1093/hmg/dds040Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
resolves10.1038/cr.2013.2XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells
resolves10.1093/emboj/cdg537Caspase‐12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein
resolves10.1073/pnas.0711094105Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis
resolves10.1038/nature11058Sustained translational repression by eIF2α-P mediates prion neurodegeneration
resolves10.1126/scitranslmed.3006767Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
resolves10.1242/jcs.123000The
<i>ire-1</i>
ER Stress-Response Pathway is Required for Normal Secretory- Protein Metabolism in
<i>C. elegans</i>
resolves10.1038/nn.3486Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
resolves10.1016/j.cmet.2013.11.002TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys
resolves10.1073/pnas.0911991107Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78
resolves10.1038/cddis.2012.8Activation of the unfolded protein response enhances motor recovery after spinal cord injury
resolves10.1016/j.nbd.2013.04.021Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury
resolves10.3892/etm.2012.745C/EBP homologous protein (CHOP) mediates neuronal apoptosis in rats with spinal cord injury
resolves10.1002/glia.21191Attenuating the endoplasmic reticulum stress response improves functional recovery after spinal cord injury
resolves10.1089/neu.2011.1940Deletion of the Pro-Apoptotic Endoplasmic Reticulum Stress Response Effector CHOP Does Not Result in Improved Locomotor Function after Severe Contusive Spinal Cord Injury
resolves10.1016/j.neuron.2011.11.026Differential Effects of Unfolded Protein Response Pathways on Axon Injury-Induced Death of Retinal Ganglion Cells
resolves10.1016/j.jvs.2010.06.172Sodium 4-phenylbutyrate protects against spinal cord ischemia by inhibition of endoplasmic reticulum stress
resolves10.1038/nn.2273Endoplasmic reticulum stress in disorders of myelinating cells
resolves10.1093/brain/awl044Interferon-γ inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress
resolves10.2353/ajpath.2008.080449Enhanced Integrated Stress Response Promotes Myelinating Oligodendrocyte Survival in Response to Interferon-γ
resolves10.1172/JCI29571The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage
resolves10.1523/JNEUROSCI.1636-12.2013Oligodendrocyte-Specific Activation of PERK Signaling Protects Mice against Experimental Autoimmune Encephalomyelitis
resolves10.1084/jem.20122005Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice
resolves10.1016/j.neuron.2007.12.021Ablation of the UPR-Mediator CHOP Restores Motor Function and Reduces Demyelination in Charcot-Marie-Tooth 1B Mice
resolves10.1093/hmg/ddm324ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones
resolves10.1093/hmg/ddi451Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL
resolves10.1016/j.molcel.2004.08.029GM1-Ganglioside-Mediated Activation of the Unfolded Protein Response Causes Neuronal Death in a Neurodegenerative Gangliosidosis
resolves10.1016/j.molcel.2009.10.021GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis
resolves10.1038/70265Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
resolves10.1101/gad.992302ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
resolves10.1038/47513Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
resolves10.1093/hmg/ddr274Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death
resolves10.1523/JNEUROSCI.5368-11.2012Accumulation of Toxic α-Synuclein Oligomer within Endoplasmic Reticulum Occurs in α-Synucleinopathy<i>In Vivo</i>
resolves10.1073/pnas.0509227103Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model
resolves10.1096/fj.07-092783The endoplasmic reticulum‐Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS
resolves10.1038/nn1603Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
resolves10.1523/JNEUROSCI.4253-04.2005Impaired Extracellular Secretion of Mutant Superoxide Dismutase 1 Associates with Neurotoxicity in Familial Amyotrophic Lateral Sclerosis
resolves10.1371/journal.pone.0081170ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation
resolves10.1371/journal.ppat.1000608Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones
resolves10.1093/brain/awp267Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis
resolves10.1038/nature04782S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
resolves10.1038/nchembio.467Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins
resolves10.1101/gad.1673408Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity
resolves10.1523/JNEUROSCI.5397-12.2013Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation
resolves10.1126/science.1129462α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models
resolves10.1091/mbc.e09-09-0801α-Synuclein Delays Endoplasmic Reticulum (ER)-to-Golgi Transport in Mammalian Cells by Antagonizing ER/Golgi SNAREs
resolves10.1093/hmg/dds206Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity
resolves10.1038/emboj.2013.131The ALS8 protein VAPB interacts with the ER–Golgi recycling protein YIF1A and regulates membrane delivery into dendrites
resolves10.1093/hmg/ddt594The amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality control
resolves10.1523/JNEUROSCI.3873-06.2006Mutant huntingtin Impairs the Post-Golgi Trafficking of Brain-Derived Neurotrophic Factor But Not Its Val66Met Polymorphism
resolves10.1096/fj.09-147850A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum
resolves10.1016/j.bbrc.2005.10.061siRNA-mediated inhibition of endogenous Huntington disease gene expression induces an aberrant configuration of the ER network in vitro
resolves10.1111/cns.12064Polymorphism −116<scp>C</scp>/<scp>G</scp>of Human<scp>X</scp>‐box‐Binding Protein 1 Promoter is Associated with Risk of<scp>A</scp>lzheimer's Disease
resolves10.1038/ng1235Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder
resolves10.1038/nature10353Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
resolves10.1007/s00401-013-1090-0Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology
resolves10.1016/j.nbd.2010.08.014Impaired ATF6α processing, decreased Rheb and neuronal cell cycle re-entry in Huntington's disease
resolves10.1074/jbc.M605049200Characterization of Amyotrophic Lateral Sclerosis-linked P56S Mutation of Vesicle-associated Membrane Protein-associated Protein B (VAPB/ALS8)
resolves10.1111/j.1471-4159.2008.05857.xALS‐linked P56S‐VAPB, an aggregated loss‐of‐function mutant of VAPB, predisposes motor neurons to ER stress‐related death by inducing aggregation of co‐expressed wild‐type VAPB
resolves10.1371/journal.pone.0022354Dysregulated LRRK2 Signaling in Response to Endoplasmic Reticulum Stress Leads to Dopaminergic Neuron Degeneration in C. elegans
resolves10.1074/jbc.M808255200Caenorhabditits elegans LRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth
resolves10.1016/S0092-8674(00)81667-0A Role for Presenilin-1 in Nuclear Accumulation of Ire1 Fragments and Induction of the Mammalian Unfolded Protein Response
resolves10.1016/S0896-6273(03)00366-0Huntingtin and Huntingtin-Associated Protein 1 Influence Neuronal Calcium Signaling Mediated by Inositol-(1,4,5) Triphosphate Receptor Type 1
resolves10.1093/hmg/ddr502The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins
resolves10.1172/JCI61332Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling
resolves10.1038/nchembio.368Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis
resolves10.1371/journal.pone.0015658Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress
resolves10.1196/annals.1397.085Altered Subcellular Distribution of the Alzheimer's Amyloid Precursor Protein Under Stress Conditions
resolves10.1074/jbc.273.40.25552The Chaperone BiP/GRP78 Binds to Amyloid Precursor Protein and Decreases Aβ40 and Aβ42 Secretion
resolves10.1016/j.neuron.2008.10.047Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis
resolves10.1038/cdd.2010.142Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress
resolves10.1242/jcs.127340ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1
resolves10.1128/MCB.00315-13Establishing Links between Endoplasmic Reticulum-Mediated Hormesis and Cancer
resolves10.1128/MCB.00922-10Protein Misfolding Induces Hypoxic Preconditioning via a Subset of the Unfolded Protein Response Machinery
resolves10.4161/auto.5.8.10247XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy
resolves10.1016/j.cell.2007.01.050eIF2α Phosphorylation Bidirectionally Regulates the Switch from Short- to Long-Term Synaptic Plasticity and Memory
resolves10.1038/nature03897Translational control of hippocampal synaptic plasticity and memory by the eIF2α kinase GCN2
resolves10.1016/j.cell.2011.11.029Suppression of PKR Promotes Network Excitability and Enhanced Cognition by Interferon-γ-Mediated Disinhibition
resolves10.7554/eLife.00498Pharmacological brake-release of mRNA translation enhances cognitive memory
resolves10.1016/j.celrep.2012.04.010Brain-Specific Disruption of the eIF2α Kinase PERK Decreases ATF4 Expression and Impairs Behavioral Flexibility
resolves10.1074/jbc.M704300200The Role of Brain-derived Neurotrophic Factor (BDNF)-induced XBP1 Splicing during Brain Development
resolves10.1091/mbc.e04-02-0108The Unfolded Protein Response Regulates Glutamate Receptor Export from the Endoplasmic Reticulum
resolves10.1016/j.celrep.2013.09.046Xbp1-Independent Ire1 Signaling Is Required for Photoreceptor Differentiation and Rhabdomere Morphogenesis in Drosophila
resolves10.1016/j.neures.2010.07.2042Behavioral and gene expression analyses in heterozygous XBP1 knockout mice: Possible contribution of chromosome 11qA1 locus to prepulse inhibition
resolves10.1371/journal.pgen.1002833Drosophila Fatty Acid Transport Protein Regulates Rhodopsin-1 Metabolism and Is Required for Photoreceptor Neuron Survival
resolves10.1073/pnas.1015959108Light-dependent and circadian clock-regulated activation of sterol regulatory element-binding protein, X-box-binding protein 1, and heat shock factor pathways
resolves10.1016/j.neuroscience.2012.02.016Salubrinal, an endoplasmic reticulum stress blocker, modulates sleep homeostasis and activation of sleep- and wake-regulatory neurons
resolves10.1073/pnas.0902882106Collapse of proteostasis represents an early molecular event in
<i>Caenorhabditis elegans</i>
aging
resolves10.1038/embor.2012.100Organismal regulation of XBP‐1‐mediated unfolded protein response during development and immune activation
resolves10.1073/pnas.1002575107Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
resolves10.1083/jcb.201003138Regulation of basal cellular physiology by the homeostatic unfolded protein response
resolves10.1002/iub.1224Role of the unfolded protein response in organ physiology: Lessons from mouse models
resolves10.1096/fj.13-234864Unfolded protein response signaling by transcription factor XBP‐1 regulates ADAM10 and is affected in Alzheimer's disease
resolves10.1002/path.3969The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies
resolves10.1016/j.brainres.2004.07.026Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology
resolves10.1093/brain/awm190Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis
resolves10.1016/j.nbd.2009.08.013Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice
resolves10.1097/NEN.0b013e3181d44992Endoplasmic Reticulum Stress in Motor Neurons of the Spinal Cord in Sporadic Amyotrophic Lateral Sclerosis
resolves10.1016/j.bbrc.2012.03.033AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington’s disease
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