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A novel regulator of ER Ca2+ drives Hippo-mediated tumorigenesis
53/53 checkable references clean · checked 2026-07-22
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
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The 53 checked references that resolve
resolves10.1038/nrc2374
Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival
resolves10.3389/fonc.2017.00199
Endoplasmic Reticulum–Mitochondria Calcium Communication and the Regulation of Mitochondrial Metabolism in Cancer: A Novel Potential Target
resolves10.1158/0008-5472.CAN-05-0026
Haploinsufficiency of <i>Atp2a2</i>, Encoding the Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 2 Ca2+ Pump, Predisposes Mice to Squamous Cell Tumors via a Novel Mode of Cancer Susceptibility
resolves10.18632/oncotarget.1903
Elevated Orai1 expression mediates tumor-promoting intracellular Ca2+ oscillations in human esophageal squamous cell carcinoma
resolves10.1158/1535-7163.MCT-10-0923
ORAI1-Mediated Calcium Influx in Lactation and in Breast Cancer
resolves10.1016/j.ceca.2010.09.005
The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma
resolves10.1242/dev.121.4.1053
Identifying tumor suppressors in genetic mosaics: the <i>Drosophila lats</i> gene encodes a putative protein kinase
resolves10.1016/j.cell.2005.06.007
The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP
resolves10.1101/gad.9.5.534
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation.
resolves10.1038/ncb1051
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
resolves10.1038/ncb1050
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
resolves10.1016/S0092-8674(03)00549-X
hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell Proliferation and Promotes Apoptosis in Conjunction with salvador and warts
resolves10.1016/S0166-2236(00)01791-4
Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development
resolves10.1016/j.celrep.2017.05.092
PP6 Disruption Synergizes with Oncogenic Ras to Promote JNK-Dependent Tumor Growth and Invasion
resolves10.1038/nature08702
Interaction between RasV12 and scribbled clones induces tumour growth and invasion
resolves10.1093/emboj/cdf306
Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway
resolves10.1038/onc.2015.137
Rho1–Wnd signaling regulates loss-of-cell polarity-induced cell invasion in Drosophila
resolves10.1016/j.cub.2006.04.042
Loss of Cell Polarity Drives Tumor Growth and Invasion through JNK Activation in Drosophila
resolves10.1038/sj.emboj.7601401
JNK‐ and Fos‐regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila
resolves10.1038/nature11452
Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila
resolves10.1093/jb/mvu045
Dissecting tumour heterogeneity in flies: genetic basis of interclonal oncogenic cooperation
resolves10.1038/s41388-018-0201-8
JNK and Yorkie drive tumor progression by generating polyploid giant cells in Drosophila
resolves10.1371/journal.pgen.1001140
dMyc Functions Downstream of Yorkie to Promote the Supercompetitive Behavior of Hippo Pathway Mutant Cells
resolves10.1016/j.devcel.2010.09.009
Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of Yap
resolves10.1038/ncb1339
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
resolves10.1038/onc.2016.463
Myc suppresses tumor invasion and cell migration by inhibiting JNK signaling
resolves10.1073/pnas.0611666104
Basement membrane remodeling is essential for
<i>Drosophila</i>
disc eversion and tumor invasion
resolves10.1242/dev.01949
Puckered, a<i>Drosophila</i>MAPK phosphatase, ensures cell viability by antagonizing JNK-induced apoptosis
resolves10.1146/annurev-physiol-030212-183707
Coping with Endoplasmic Reticulum Stress in the Cardiovascular System
resolves10.1038/sj.emboj.7601477
Unfolded protein response in a Drosophila model for retinal degeneration
resolves10.1073/pnas.1715165115
POSH regulates Hippo signaling through ubiquitin-mediated expanded degradation
resolves10.1074/jbc.M601056200
Direct Interaction of the Molecular Scaffolds POSH and JIP Is Required for Apoptotic Activation of JNKs
resolves10.1016/j.febslet.2006.05.005
POSH, a scaffold protein for JNK signaling, binds to ALG‐2 and ALIX in <i>Drosophila</i>
resolves10.1093/emboj/cdg021
POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis
resolves10.1128/MCB.25.22.9949-9959.2005
Regulation of Apoptotic c-Jun N-Terminal Kinase Signaling by a Stabilization-Based Feed-Forward Loop
resolves10.1083/jcb.200611036
The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp
resolves10.1016/j.devcel.2017.05.001
THADA Regulates the Organismal Balance between Energy Storage and Heat Production
The 1 reference without a DOI — listed, not checked
no DOI — not checkedSun G, Irvine KD. Ajuba family proteins link JNK to Hippo signaling. Sci Signal. 2013;6:ra81.
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