Reference health
Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development
53/53 checkable references clean · checked 2026-07-23
Every reference with a DOI in the deposited reference list resolved to a known work in Crossref or DataCite at the dated check, and none carried a retraction, withdrawal, or removal notice.
8 without a DOI — not checked. A reference deposited without a DOI is never matched by title or guessed at; it stays outside the checked set, and this line discloses that.
The 53 checked references that resolve
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Germ cell neoplasia <i>in situ</i> (<scp>GCNIS</scp>): evolution of the current nomenclature for testicular pre‐invasive germ cell malignancy
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Germ cell neoplasia in situ: The precursor cell for invasive germ cell tumors of the testis
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Imprints and <i>DPPA3</i> are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors
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Maintaining success, reducing treatment burden, focusing on survivorship: highlights from the third European consensus conference on diagnosis and treatment of germ-cell cancer
resolves10.1158/0008-5472.CAN-05-0471
Amplification and Overexpression of the <i>KIT</i> Gene Is Associated with Progression in the Seminoma Subtype of Testicular Germ Cell Tumors of Adolescents and Adults
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Patient with two secondary somatic-type malignancies in a late recurrence of a testicular non-seminoma: illustration of potential and flaw of the cancer stem cell therapy concept
resolves10.1200/JCO.2002.20.6.1551
Role of P53 and MDM2 in Treatment Response of Human Germ Cell Tumors
resolves10.1016/j.neo.2014.12.005
Exome Sequencing of Bilateral Testicular Germ Cell Tumors Suggests Independent Development Lineages
resolves10.1016/j.eururo.2014.12.040
Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas
resolves10.1038/ncomms6973
Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours
resolves10.1038/sj.onc.1203950
Overrepresentation of the short arm of chromosome 12 is related to invasive growth of human testicular seminomas and nonseminomas
resolves10.18632/oncotarget.13380
Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis
resolves10.1007/s00401-016-1557-x
Recurrent neomorphic mutations of MTOR in central nervous system and testicular germ cell tumors may be targeted for therapy
resolves10.1016/j.celrep.2018.05.039
Integrated Molecular Characterization of Testicular Germ Cell Tumors
resolves10.1111/j.1365-2559.2011.03767.x
Diagnosis of testicular carcinoma <i>in situ</i>‘(intratubular and microinvasive)’ seminoma and embryonal carcinoma using direct enzymatic alkaline phosphatase reactivity on frozen histological sections
resolves10.1126/science.1181498
Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays
resolves10.1093/neuonc/nov182
Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial
resolves10.1371/journal.pone.0208002
TargetClone: A multi-sample approach for reconstructing subclonal evolution of tumors
resolves10.1371/journal.pone.0122146
Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors
resolves10.1038/srep20944
Digital Sorting of Pure Cell Populations Enables Unambiguous Genetic Analysis of Heterogeneous Formalin-Fixed Paraffin-Embedded Tumors by Next Generation Sequencing
resolves10.1038/nature17676
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
resolves10.1371/journal.pone.0178169
Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline
resolves10.1200/JCO.2016.68.7798
Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors
resolves10.1172/JCI42002
Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma
resolves10.1038/ncb2956
Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma
resolves10.1126/science.aab1785
Somatic mutation in single human neurons tracks developmental and transcriptional history
resolves10.1038/nature21703
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo
resolves10.1054/bjoc.2001.1889
Chromosomal imbalances associated with carcinoma in situ and associated testicular germ cell tumours of adolescents and adults
resolves10.1002/gcc.10244
High‐resolution comparative genomic hybridization detects extra chromosome arm 12p material in most cases of carcinoma in situ adjacent to overt germ cell tumors, but not before the invasive tumor development
resolves10.1002/gcc.2870140208
No recurrent structural abnormalities apart from i(12p) in primary germ cell tumors of the adult testis
resolves10.1016/j.yexcr.2010.04.030
Up-regulation of the embryonic self-renewal network through reversible polyploidy in irradiated p53-mutant tumour cells
resolves10.1186/1747-1028-1-4
Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice
resolves10.1016/j.cell.2006.02.037
A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors
resolves10.1016/j.eururo.2009.06.014
Therapeutic Potential of Mdm2 Inhibition in Malignant Germ Cell Tumours
resolves10.1038/ng.3934
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
resolves10.1016/j.dnarep.2007.02.011
Differences in DNA double strand breaks repair in male germ cell types: Lessons learned from a differential expression of Mdc1 and 53BP1
resolves10.1016/j.eururo.2014.07.011
Gonadal Maldevelopment as Risk Factor for Germ Cell Cancer: Towards a Clinical Decision Model
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Etiology and early pathogenesis of malignant testicular germ cell tumors: towards possibilities for preinvasive diagnosis
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Understanding mutagenesis through delineation of mutational signatures in human cancer
The 8 references without a DOI — listed, not checked
no DOI — not checkedUlbright, T.M. et al. Germ cell tumours. (eds H. M., Humphrey, P.A., Ulbright, T.M., Reuter, V.E.) in WHO Classification of Tumours of the Urinary System and Male Genital Organs. 4th ed. pp. 189–226 (IARC Press, Lyon, 2016).
no DOI — not checkedChaganti, R. S. & Houldsworth, J. Genetics and biology of adult human male germ cell tumors. Cancer Res. 60, 1475–1482 (2000).
no DOI — not checkedOosterhuis, J. W. et al. Ploidy of primary germ cell tumors of the testis. Pathogenetic and clinical relevance. Lab. Invest. 60, 14–21 (1989).
no DOI — not checkedBlokzijl F, Janssen R, Van Boxtel R, Cuppen E. MutationalPatterns: An Integrative R Package for Studying Patterns in Base Substitution Catalogues. http://www.biorxivorg/content/early/2016/10/17/071761 (2016).
no DOI — not checkedHovestadt V, Zapatka M. Conumee: Enhanced Copy-Number Variation Analysis Using Illumina DNA Methylation Arrays. R package version 1.6.0. http://www.packages/packages/conumee/ (2015).
no DOI — not checkedTCGA-TGCT. Testicular Germ Cell Cancer (TCGA, Provisional). http://www.cbioportalorg/study?id=tgct_tcga#summary (2016).
no DOI — not checkedStevens, L. C. Experimental production of testicular teratomas in mice of strains 129, A/He, and their F1 hybrids. J. Natl. Cancer Inst. 44, 923–929 (1970).
no DOI — not checkedTCGA-testis. TCGA-Testicular Germ Cell Cancers. http://wwwcbioportalorg/ (2018).
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